{"id":122683,"date":"2026-01-14T16:14:56","date_gmt":"2026-01-14T07:14:56","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?p=122683"},"modified":"2026-03-31T16:13:37","modified_gmt":"2026-03-31T07:13:37","slug":"myhre-syndrome-guide","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/","title":{"rendered":"\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\uff08Myhre Syndrome\uff09"},"content":{"rendered":"\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u3068\u3044\u3046\u3001\u975e\u5e38\u306b\u7a00\u3067\u805e\u304d\u6163\u308c\u306a\u3044\u8a3a\u65ad\u540d\u3092\u805e\u304d\u3001\u60c5\u5831\u3092\u6c42\u3081\u3066\u3053\u306e\u30da\u30fc\u30b8\u306b\u305f\u3069\u308a\u7740\u304b\u308c\u305f\u3054\u5bb6\u65cf\u306e\u65b9\u3078\u3002<\/p>\n\n\n\n<p>\u533b\u5e2b\u304b\u3089\u300c\u907a\u4f1d\u5b50\u306e\u5909\u5316\u306b\u3088\u308b\u75c5\u6c17\u3067\u3059\u300d\u3068\u8aac\u660e\u3092\u53d7\u3051\u3001\u3055\u3089\u306b\u300cSMAD4\u3068\u3044\u3046\u907a\u4f1d\u5b50\u304c\u539f\u56e0\u3067\u3059\u300d\u3084\u300c\u7b4b\u8089\u8cea\u306a\u4f53\u3064\u304d\u304c\u7279\u5fb4\u3067\u3059\u300d\u3068\u3044\u3063\u305f\u8a71\u3092\u3055\u308c\u3066\u3001\u307e\u3060\u5177\u4f53\u7684\u306a\u30a4\u30e1\u30fc\u30b8\u304c\u6e67\u304b\u305a\u306b\u6238\u60d1\u3063\u3066\u3044\u3089\u3063\u3057\u3083\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3042\u308b\u3044\u306f\u3001\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u3067\u691c\u7d22\u3057\u3066\u3082\u65e5\u672c\u8a9e\u306e\u8a73\u3057\u3044\u60c5\u5831\u304c\u5c11\u306a\u304f\u3001\u5c06\u6765\u3078\u306e\u4e0d\u5b89\u3092\u611f\u3058\u3066\u3044\u3089\u3063\u3057\u3083\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u75c5\u6c17\u306f\u30011981\u5e74\u306b\u30a2\u30e1\u30ea\u30ab\u306e\u533b\u5e2b\u3067\u3042\u308b\u30de\u30a4\u30e4\u30fc\u535a\u58eb\u305f\u3061\u306b\u3088\u3063\u3066\u521d\u3081\u3066\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u7d50\u5408\u7d44\u7e54\u3068\u3044\u3046\u3001\u4f53\u306e\u7d30\u80de\u3068\u7d30\u80de\u3092\u3064\u306a\u304e\u5408\u308f\u305b\u305f\u308a\u3001\u4f53\u3092\u652f\u3048\u305f\u308a\u3059\u308b\u7d44\u7e54\u306b\u5909\u5316\u304c\u8d77\u304d\u308b\u751f\u307e\u308c\u3064\u304d\u306e\u4f53\u8cea\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u6700\u5927\u306e\u7279\u5fb4\u306f\u3001\u8eab\u9577\u306f\u4f4e\u3044\u3082\u306e\u306e\u3001\u307e\u308b\u3067\u30b9\u30dd\u30fc\u30c4\u9078\u624b\u306e\u3088\u3046\u306b\u7b4b\u8089\u8cea\u3067\u304c\u3063\u3061\u308a\u3068\u3057\u305f\u4f53\u683c\u3092\u3057\u3066\u3044\u308b\u3053\u3068\u3067\u3059\u3002\u307e\u305f\u3001\u76ae\u819a\u304c\u539a\u304f\u306a\u3063\u305f\u308a\u3001\u95a2\u7bc0\u304c\u786c\u304f\u306a\u3063\u305f\u308a\u3001\u8074\u529b\u304c\u4f4e\u4e0b\u3057\u305f\u308a\u3068\u3044\u3063\u305f\u75c7\u72b6\u3082\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u3057\u3066\u3001\u3053\u306e\u75c5\u6c17\u306b\u304a\u3044\u3066\u3054\u5bb6\u65cf\u3068\u533b\u7642\u8005\u304c\u6700\u3082\u5171\u6709\u3057\u3066\u304a\u304f\u3079\u304d\u91cd\u8981\u306a\u60c5\u5831\u306f\u3001\u4f53\u304c\u50b7\u3092\u6cbb\u305d\u3046\u3068\u3059\u308b\u53cd\u5fdc\u304c\u5f37\u3059\u304e\u308b\u305f\u3081\u306b\u3001\u624b\u8853\u3084\u602a\u6211\u306e\u3042\u3068\u306b\u7d44\u7e54\u304c\u786c\u304f\u306a\u3063\u3066\u3057\u307e\u3046\u300c\u7dda\u7dad\u5316\u300d\u3068\u3044\u3046\u73fe\u8c61\u304c\u8d77\u304d\u3084\u3059\u3044\u3068\u3044\u3046\u70b9\u3067\u3059\u3002\u3053\u308c\u306f\u3001\u65e5\u3005\u306e\u751f\u6d3b\u3084\u533b\u7642\u51e6\u7f6e\u3092\u53d7\u3051\u308b\u4e0a\u3067\u3001\u77e5\u3063\u3066\u304a\u304f\u3079\u304d\u3068\u3066\u3082\u5927\u5207\u306a\u30dd\u30a4\u30f3\u30c8\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u975e\u5e38\u306b\u5e0c\u5c11\u306a\u75be\u60a3\u3067\u3059\u304c\u3001\u8fd1\u5e74\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u6280\u8853\u304c\u9032\u6b69\u3057\u305f\u3053\u3068\u3067\u3001\u8a3a\u65ad\u3055\u308c\u308b\u60a3\u8005\u3055\u3093\u304c\u4e16\u754c\u4e2d\u3067\u5897\u3048\u3066\u304d\u3066\u304a\u308a\u3001\u30a2\u30e1\u30ea\u30ab\u306b\u306f\u300cMyhre Syndrome Foundation\u300d\u3068\u3044\u3046\u60a3\u8005\u56e3\u4f53\u3082\u3042\u308a\u3001\u7814\u7a76\u304c\u6d3b\u767a\u306b\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305a\u6700\u521d\u306b\u304a\u4f1d\u3048\u3057\u305f\u3044\u306e\u306f\u3001\u6b63\u3057\u3044\u77e5\u8b58\u3092\u6301\u3064\u3053\u3068\u304c\u3001\u304a\u5b50\u3055\u3093\u306e\u5065\u5eb7\u3068\u5b89\u5168\u3092\u5b88\u308b\u4e00\u756a\u306e\u529b\u306b\u306a\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u304a\u5b50\u3055\u3093\u306b\u306f\u3001\u305d\u306e\u5b50\u3060\u3051\u306e\u7d20\u6674\u3089\u3057\u3044\u500b\u6027\u3068\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3042\u307e\u308a\u6050\u308c\u3059\u304e\u305a\u3001\u4e00\u3064\u3072\u3068\u3064\u77e5\u8b58\u3092\u6574\u7406\u3057\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n<!--nipt_mono-->\r\n<div class=\"nipt-mono\">\r\n    <div class=\"nipt-mono-btn\">\r\n   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href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#6_%E5%91%BC%E5%90%B8%E5%99%A8%E3%81%AE%E7%97%87%E7%8A%B6%EF%BC%88%E6%9C%80%E3%82%82%E6%B3%A8%E6%84%8F%E3%81%8C%E5%BF%85%E8%A6%81%EF%BC%89\" >6. \u547c\u5438\u5668\u306e\u75c7\u72b6\uff08\u6700\u3082\u6ce8\u610f\u304c\u5fc5\u8981\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#7_%E3%81%9D%E3%81%AE%E4%BB%96%E3%81%AE%E7%97%87%E7%8A%B6\" >7. \u305d\u306e\u4ed6\u306e\u75c7\u72b6<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#%E5%8E%9F%E5%9B%A0\" >\u539f\u56e0<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#SMAD4%E9%81%BA%E4%BC%9D%E5%AD%90%E3%81%AE%E5%BD%B9%E5%89%B2\" >SMAD4\u907a\u4f1d\u5b50\u306e\u5f79\u5272<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#%E4%BD%95%E3%81%8C%E8%B5%B7%E3%81%8D%E3%81%A6%E3%81%84%E3%82%8B%E3%81%AE%E3%81%8B%EF%BC%88%E6%A9%9F%E8%83%BD%E7%8D%B2%E5%BE%97%E5%9E%8B%E5%A4%89%E7%95%B0%EF%BC%89\" >\u4f55\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u304b\uff08\u6a5f\u80fd\u7372\u5f97\u578b\u5909\u7570\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#%E9%81%BA%E4%BC%9D%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6\" >\u907a\u4f1d\u306b\u3064\u3044\u3066<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#%E8%A8%BA%E6%96%AD%E3%81%A8%E6%A4%9C%E6%9F%BB\" >\u8a3a\u65ad\u3068\u691c\u67fb<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#1_%E8%87%A8%E5%BA%8A%E8%A8%BA%E6%96%AD\" >1. \u81e8\u5e8a\u8a3a\u65ad<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#2_%E9%81%BA%E4%BC%9D%E5%AD%A6%E7%9A%84%E6%A4%9C%E6%9F%BB\" >2. \u907a\u4f1d\u5b66\u7684\u691c\u67fb<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#3_%E5%85%A8%E8%BA%AB%E3%81%AE%E8%A9%95%E4%BE%A1%E6%A4%9C%E6%9F%BB\" >3. \u5168\u8eab\u306e\u8a55\u4fa1\u691c\u67fb<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#%E6%B2%BB%E7%99%82%E3%81%A8%E7%AE%A1%E7%90%86\" >\u6cbb\u7642\u3068\u7ba1\u7406<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#1_%E3%80%8C%E7%B7%9A%E7%B6%AD%E5%8C%96%E3%80%8D%E3%82%92%E9%98%B2%E3%81%90%E3%81%9F%E3%82%81%E3%81%AE%E6%9C%80%E9%87%8D%E8%A6%81%E4%BA%8B%E9%A0%85\" >1. \u300c\u7dda\u7dad\u5316\u300d\u3092\u9632\u3050\u305f\u3081\u306e\u6700\u91cd\u8981\u4e8b\u9805<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#2_%E8%96%AC%E7%89%A9%E7%99%82%E6%B3%95%E3%81%AE%E5%8F%AF%E8%83%BD%E6%80%A7\" >2. \u85ac\u7269\u7642\u6cd5\u306e\u53ef\u80fd\u6027<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#3_%E3%83%AA%E3%83%8F%E3%83%93%E3%83%AA%E3%83%86%E3%83%BC%E3%82%B7%E3%83%A7%E3%83%B3%EF%BC%88%E7%99%82%E8%82%B2%EF%BC%89\" >3. \u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\uff08\u7642\u80b2\uff09<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-26\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#4_%E8%81%B4%E8%A6%9A%E3%81%AE%E7%AE%A1%E7%90%86\" >4. \u8074\u899a\u306e\u7ba1\u7406<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-27\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#5_%E5%BE%AA%E7%92%B0%E5%99%A8%E3%83%BB%E5%91%BC%E5%90%B8%E5%99%A8%E3%81%AE%E5%AE%9A%E6%9C%9F%E6%A4%9C%E8%A8%BA\" >5. \u5faa\u74b0\u5668\u30fb\u547c\u5438\u5668\u306e\u5b9a\u671f\u691c\u8a3a<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-28\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/#%E3%81%BE%E3%81%A8%E3%82%81\" >\u307e\u3068\u3081<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%A6%82%E8%A6%81%EF%BC%9A%E3%81%A9%E3%81%AE%E3%82%88%E3%81%86%E3%81%AA%E7%97%85%E6%B0%97%E3%81%8B\"><\/span><strong>\u6982\u8981\uff1a\u3069\u306e\u3088\u3046\u306a\u75c5\u6c17\u304b<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u307e\u305a\u3001\u3053\u306e\u75c5\u6c17\u304c\u3069\u306e\u3088\u3046\u306a\u4f4d\u7f6e\u3065\u3051\u306b\u3042\u308b\u306e\u304b\u3001\u305d\u3057\u3066\u3069\u306e\u3088\u3046\u306a\u7279\u5fb4\u304c\u3042\u308b\u306e\u304b\u3092\u5168\u4f53\u50cf\u3068\u3057\u3066\u7406\u89e3\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%97%85%E6%B0%97%E3%81%AE%E5%AE%9A%E7%BE%A9\"><\/span><strong>\u75c5\u6c17\u306e\u5b9a\u7fa9<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306f\u3001\u7d50\u5408\u7d44\u7e54\u75be\u60a3\u3068\u547c\u3070\u308c\u308b\u30b0\u30eb\u30fc\u30d7\u306b\u5c5e\u3059\u308b\u5148\u5929\u6027\u306e\u75be\u60a3\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7d50\u5408\u7d44\u7e54\u3068\u306f\u3001\u9aa8\u3001\u8edf\u9aa8\u3001\u8171\u3001\u76ae\u819a\u3001\u8840\u7ba1\u306a\u3069\u3001\u4f53\u3092\u5f62\u4f5c\u308a\u3001\u652f\u3048\u308b\u305f\u3081\u306e\u7d44\u7e54\u306e\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u539f\u56e0\u3068\u306a\u308bSMAD4\u907a\u4f1d\u5b50\u306e\u50cd\u304d\u304c\u5909\u308f\u308b\u3053\u3068\u3067\u3001\u3053\u306e\u7d50\u5408\u7d44\u7e54\u306e\u4f5c\u3089\u308c\u65b9\u3084\u4fee\u5fa9\u306e\u3055\u308c\u65b9\u306b\u5909\u5316\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%BA%AB%E4%BD%93%E7%9A%84%E3%81%AA%E7%89%B9%E5%BE%B4%E3%81%AE%E3%83%91%E3%83%A9%E3%83%89%E3%83%83%E3%82%AF%E3%82%B9\"><\/span><strong>\u8eab\u4f53\u7684\u306a\u7279\u5fb4\u306e\u30d1\u30e9\u30c9\u30c3\u30af\u30b9<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u3053\u306e\u75c5\u6c17\u306e\u898b\u305f\u76ee\u306e\u7279\u5fb4\u306f\u975e\u5e38\u306b\u30e6\u30cb\u30fc\u30af\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u591a\u304f\u306e\u767a\u9054\u969c\u5bb3\u3084\u5148\u5929\u6027\u75be\u60a3\u3067\u306f\u3001\u7b4b\u8089\u306e\u5f35\u308a\u304c\u5f31\u304f\u3001\u4f53\u304c\u67d4\u3089\u304b\u3044\u300c\u4f4e\u7dca\u5f35\u300d\u3068\u3044\u3046\u72b6\u614b\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u306e\u3067\u3059\u304c\u3001\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306f\u305d\u306e\u9006\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7b4b\u8089\u304c\u3057\u3063\u304b\u308a\u3068\u767a\u9054\u3057\u3066\u304a\u308a\u3001\u5c0f\u3055\u3044\u9803\u304b\u3089\u975e\u5e38\u306b\u7b4b\u8089\u8cea\u3067\u3001\u304c\u3063\u3061\u308a\u3068\u3057\u305f\u4f53\u683c\u3092\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u305d\u306e\u4e00\u65b9\u3067\u95a2\u7bc0\u306e\u52d5\u304d\u306f\u786c\u304f\u3001\u52d5\u304b\u3057\u306b\u304f\u3044\u3068\u3044\u3046\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u300c\u898b\u305f\u76ee\u306f\u529b\u5f37\u304f\u3066\u52d5\u304d\u3084\u3059\u305d\u3046\u306a\u306e\u306b\u3001\u5b9f\u969b\u306b\u306f\u4f53\u304c\u786c\u304f\u3066\u52d5\u304d\u306b\u304f\u3044\u300d\u3068\u3044\u3046\u30d1\u30e9\u30c9\u30c3\u30af\u30b9\uff08\u9006\u8aac\u7684\u306a\u72b6\u614b\uff09\u304c\u3001\u3053\u306e\u75c5\u6c17\u306e\u7279\u5fb4\u306e\u4e00\u3064\u3068\u8a00\u3048\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E9%80%B2%E8%A1%8C%E6%80%A7%E3%81%AE%E7%B7%9A%E7%B6%AD%E5%8C%96%E3%83%AA%E3%82%B9%E3%82%AF\"><\/span><strong>\u9032\u884c\u6027\u306e\u7dda\u7dad\u5316\u30ea\u30b9\u30af<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u3092\u7406\u89e3\u3059\u308b\u4e0a\u3067\u6700\u3082\u91cd\u8981\u306a\u306e\u304c\u300c\u7dda\u7dad\u5316\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7dda\u7dad\u5316\u3068\u306f\u3001\u50b7\u304c\u6cbb\u308b\u904e\u7a0b\u3067\u30b3\u30e9\u30fc\u30b2\u30f3\u306a\u3069\u306e\u7d44\u7e54\u304c\u5897\u3048\u3059\u304e\u3066\u3001\u76ae\u819a\u3084\u5185\u81d3\u304c\u786c\u304f\u306a\u3063\u3066\u3057\u307e\u3046\u73fe\u8c61\u306e\u3053\u3068\u3067\u3059\u3002\u901a\u5e38\u306e\u602a\u6211\u306e\u3042\u3068\u306b\u6b8b\u308b\u50b7\u8de1\uff08\u7622\u75d5\uff09\u304c\u3001\u904e\u5270\u306b\u4f5c\u3089\u308c\u3066\u3057\u307e\u3046\u72b6\u614b\u3092\u30a4\u30e1\u30fc\u30b8\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u60a3\u8005\u3055\u3093\u306f\u3001\u624b\u8853\u3084\u708e\u75c7\u306a\u3069\u3092\u304d\u3063\u304b\u3051\u306b\u3001\u3053\u306e\u7dda\u7dad\u5316\u304c\u5f37\u304f\u8d77\u304d\u3084\u3059\u3044\u4f53\u8cea\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u547c\u5438\u3092\u3059\u308b\u305f\u3081\u306e\u7ba1\u3067\u3042\u308b\u6c17\u7ba1\u3084\u5589\u3001\u5fc3\u81d3\u3092\u5305\u3080\u819c\u306a\u3069\u306b\u5f71\u97ff\u304c\u51fa\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u3001\u614e\u91cd\u306a\u7ba1\u7406\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%99%BA%E7%94%9F%E9%A0%BB%E5%BA%A6\"><\/span><strong>\u767a\u751f\u983b\u5ea6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u975e\u5e38\u306b\u7a00\u306a\u75be\u60a3\u3067\u3042\u308a\u3001\u6b63\u78ba\u306a\u60a3\u8005\u6570\u306f\u308f\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u4e16\u754c\u4e2d\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u306e\u306f\u6570\u767e\u4f8b\u7a0b\u5ea6\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u7279\u5fb4\u7684\u306a\u4f53\u3064\u304d\u3084\u75c7\u72b6\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u77e5\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308b\u306b\u3064\u308c\u3066\u3001\u8a3a\u65ad\u3055\u308c\u308b\u6570\u306f\u5897\u3048\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%BB%E3%81%AA%E7%97%87%E7%8A%B6\"><\/span><strong>\u4e3b\u306a\u75c7\u72b6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u75c7\u72b6\u306f\u3001\u9aa8\u683c\u3001\u76ae\u819a\u3001\u611f\u899a\u5668\u3001\u5185\u81d3\u306a\u3069\u3001\u5168\u8eab\u306e\u69d8\u3005\u306a\u5834\u6240\u306b\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u500b\u4eba\u5dee\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u591a\u304f\u306e\u60a3\u8005\u3055\u3093\u306b\u5171\u901a\u3057\u3066\u898b\u3089\u308c\u308b\u30b5\u30a4\u30f3\u306b\u3064\u3044\u3066\u3001\u8a73\u3057\u304f\u898b\u3066\u3044\u304d\u307e\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E9%AA%A8%E6%A0%BC%E3%81%A8%E7%AD%8B%E8%82%89%E3%80%81%E6%88%90%E9%95%B7%E3%81%AE%E7%89%B9%E5%BE%B4\"><\/span><strong>1. \u9aa8\u683c\u3068\u7b4b\u8089\u3001\u6210\u9577\u306e\u7279\u5fb4<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u3054\u5bb6\u65cf\u304c\u6210\u9577\u904e\u7a0b\u3067\u6c17\u3065\u304f\u3053\u3068\u304c\u591a\u3044\u8eab\u4f53\u7684\u306a\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f4e\u8eab\u9577<\/p>\n\n\n\n<p>\u304a\u8179\u306e\u4e2d\u306b\u3044\u308b\u6642\u306e\u767a\u80b2\u306f\u6b63\u5e38\u7bc4\u56f2\u3067\u3042\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u304c\u3001\u751f\u307e\u308c\u3066\u304b\u3089\u5f90\u3005\u306b\u8eab\u9577\u306e\u4f38\u3073\u304c\u7de9\u3084\u304b\u306b\u306a\u308a\u3001\u6700\u7d42\u7684\u306a\u8eab\u9577\u306f\u5e73\u5747\u3088\u308a\u3082\u4f4e\u304f\u306a\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u9aa8\u306e\u6210\u9577\u304c\u901a\u5e38\u3088\u308a\u3082\u65e9\u304f\u7d42\u4e86\u3059\u308b\u50be\u5411\u304c\u3042\u308b\u305f\u3081\u3067\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7b4b\u8089\u8cea\u306a\u4f53\u683c\uff08\u7b4b\u80a5\u5927\uff09<\/p>\n\n\n\n<p>\u7279\u5225\u306a\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u306e\u306b\u3001\u80f8\u677f\u304c\u539a\u304f\u3001\u8155\u3084\u8db3\u306e\u7b4b\u8089\u304c\u9686\u8d77\u3057\u3066\u3001\u975e\u5e38\u306b\u304c\u3063\u3061\u308a\u3068\u3057\u305f\u4f53\u3064\u304d\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u80a9\u5e45\u304c\u5e83\u304f\u3001\u80f4\u4f53\u304c\u3057\u3063\u304b\u308a\u3057\u3066\u3044\u308b\u306e\u3082\u7279\u5fb4\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u95a2\u7bc0\u306e\u62d8\u7e2e\uff08\u3053\u3046\u3057\u3085\u304f\uff09<\/p>\n\n\n\n<p>\u95a2\u7bc0\u304c\u786c\u304f\u306a\u308a\u3001\u53ef\u52d5\u57df\uff08\u52d5\u304b\u305b\u308b\u7bc4\u56f2\uff09\u304c\u72ed\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u624b\u306e\u6307\u3001\u8098\u3001\u80a9\u3001\u8db3\u9996\u306a\u3069\u304c\u786c\u304f\u306a\u308a\u3084\u3059\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u624b\u304c\u5b8c\u5168\u306b\u958b\u304d\u304d\u3089\u306a\u3044\u3001\u8155\u304c\u307e\u3063\u3059\u3050\u4f38\u3073\u306a\u3044\u3001\u3064\u307e\u5148\u7acb\u3061\u306e\u3088\u3046\u306a\u6b69\u304d\u65b9\u306b\u306a\u308b\u3068\u3044\u3063\u305f\u75c7\u72b6\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9aa8\u306e\u539a\u307f<\/p>\n\n\n\n<p>\u30ec\u30f3\u30c8\u30b2\u30f3\u3092\u64ae\u308b\u3068\u3001\u982d\u306e\u9aa8\u3084\u808b\u9aa8\u3001\u624b\u8db3\u306e\u9aa8\u306a\u3069\u304c\u901a\u5e38\u3088\u308a\u3082\u539a\u304f\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E3%81%8A%E9%A1%94%E7%AB%8B%E3%81%A1%E3%81%A8%E7%9A%AE%E8%86%9A%E3%81%AE%E7%89%B9%E5%BE%B4\"><\/span><strong>2. \u304a\u9854\u7acb\u3061\u3068\u76ae\u819a\u306e\u7279\u5fb4<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306b\u306f\u3001\u5171\u901a\u3059\u308b\u7279\u5fb4\u7684\u306a\u304a\u9854\u7acb\u3061\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u304a\u9854\u7acb\u3061<\/p>\n\n\n\n<p>\u76ee\u304c\u7d30\u3044\uff08\u773c\u77bc\u88c2\u304c\u72ed\u3044\uff09\u3001\u307e\u3064\u6bdb\u304c\u9577\u3044\u3001\u5507\u304c\u8584\u3044\u3001\u53e3\u304c\u5c0f\u3055\u3044\u3001\u3042\u3054\u304c\u3057\u3063\u304b\u308a\u3057\u3066\u3044\u308b\uff08\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u5c11\u3057\u524d\u306b\u51fa\u3066\u3044\u308b\uff09\u3068\u3044\u3063\u305f\u7279\u5fb4\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9854\u5168\u4f53\u306e\u5370\u8c61\u3068\u3057\u3066\u306f\u3001\u8868\u60c5\u304c\u4e4f\u3057\u3044\u3088\u3046\u306b\u898b\u3048\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u3053\u308c\u306f\u76ae\u819a\u304c\u539a\u304f\u786c\u3044\u305f\u3081\u306b\u8868\u60c5\u7b4b\u306e\u52d5\u304d\u304c\u4f1d\u308f\u308a\u306b\u304f\u3044\u3053\u3068\u304c\u4e00\u56e0\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u76ae\u819a\u306e\u7279\u5fb4<\/p>\n\n\n\n<p>\u76ae\u819a\u304c\u539a\u304f\u3066\u786c\u3044\u611f\u3058\u304c\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u624b\u8853\u3084\u602a\u6211\u3092\u3057\u305f\u5f8c\u306e\u50b7\u8de1\u304c\u3001\u30b1\u30ed\u30a4\u30c9\u306e\u3088\u3046\u306b\u76db\u308a\u4e0a\u304c\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E8%81%B4%E8%A6%9A%E3%81%AE%E7%97%87%E7%8A%B6\"><\/span><strong>3. \u8074\u899a\u306e\u75c7\u72b6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u60a3\u8005\u3055\u3093\u306e\u5927\u591a\u6570\u306b\u3001\u96e3\u8074\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306b\u306f2\u3064\u306e\u539f\u56e0\u304c\u6df7\u3056\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u3064\u306f\u4f1d\u97f3\u6027\u96e3\u8074\u3067\u3001\u8033\u5c0f\u9aa8\u3068\u3044\u3046\u97f3\u3092\u4f1d\u3048\u308b\u9aa8\u306e\u52d5\u304d\u304c\u60aa\u304f\u306a\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3082\u3046\u4e00\u3064\u306f\u611f\u97f3\u6027\u96e3\u8074\u3067\u3001\u97f3\u3092\u611f\u3058\u308b\u795e\u7d4c\u81ea\u4f53\u306e\u50cd\u304d\u304c\u5f31\u304f\u306a\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u96e3\u8074\u306f\u8a00\u8449\u306e\u767a\u9054\u3084\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306b\u5927\u304d\u304f\u5f71\u97ff\u3059\u308b\u305f\u3081\u3001\u65e9\u671f\u767a\u898b\u3068\u5bfe\u5fdc\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_%E7%9F%A5%E7%9A%84%E7%99%BA%E9%81%94%E3%81%A8%E8%A1%8C%E5%8B%95\"><\/span><strong>4. \u77e5\u7684\u767a\u9054\u3068\u884c\u52d5<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u767a\u9054\u306b\u95a2\u3057\u3066\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u77e5\u7684\u767a\u9054\u306e\u9045\u308c<\/p>\n\n\n\n<p>\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u4e2d\u306b\u306f\u77e5\u7684\u306a\u9045\u308c\u304c\u307b\u3068\u3093\u3069\u306a\u304f\u3001\u901a\u5e38\u306e\u793e\u4f1a\u751f\u6d3b\u3092\u9001\u3063\u3066\u3044\u308b\u65b9\u3082\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8a00\u8449\u306e\u9045\u308c\u3084\u3001\u904b\u52d5\u767a\u9054\u306e\u9045\u308c\uff08\u6b69\u304d\u59cb\u3081\u306a\u3069\uff09\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u884c\u52d5\u9762\u306e\u7279\u5fb4<\/p>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/autism-spectrum-disorder-genetics\/\">\u81ea\u9589\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u75c7<\/a>\u306b\u4f3c\u305f\u7279\u5fb4\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u3060\u308f\u308a\u304c\u5f37\u304b\u3063\u305f\u308a\u3001\u5909\u5316\u3092\u5acc\u304c\u3063\u305f\u308a\u3001\u5bfe\u4eba\u95a2\u4fc2\u304c\u82e6\u624b\u3060\u3063\u305f\u308a\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u65b9\u3067\u3001\u660e\u308b\u304f\u793e\u4ea4\u7684\u306a\u6027\u683c\u306e\u304a\u5b50\u3055\u3093\u3082\u305f\u304f\u3055\u3093\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_%E5%BE%AA%E7%92%B0%E5%99%A8%EF%BC%88%E5%BF%83%E8%87%93%E3%83%BB%E8%A1%80%E7%AE%A1%EF%BC%89%E3%81%AE%E7%97%87%E7%8A%B6\"><\/span><strong>5. \u5faa\u74b0\u5668\uff08\u5fc3\u81d3\u30fb\u8840\u7ba1\uff09\u306e\u75c7\u72b6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u5fc3\u81d3\u3084\u8840\u7ba1\u306e\u58c1\u304c\u786c\u304f\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5fc3\u819c\u708e\u30fb\u5fc3\u7b4b\u75c7<\/p>\n\n\n\n<p>\u5fc3\u81d3\u3092\u5305\u3080\u819c\u304c\u786c\u304f\u306a\u308b\u53ce\u7e2e\u6027\u5fc3\u819c\u708e\u3084\u3001\u5fc3\u81d3\u306e\u7b4b\u8089\u304c\u5e83\u304c\u308a\u306b\u304f\u304f\u306a\u308b\u62d8\u675f\u578b\u5fc3\u7b4b\u75c7\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306b\u3088\u308a\u3001\u606f\u5207\u308c\u3084\u3080\u304f\u307f\u304c\u51fa\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u9ad8\u8840\u5727<\/p>\n\n\n\n<p>\u8840\u7ba1\u306e\u58c1\u304c\u786c\u304f\u306a\u308b\u3053\u3068\u3067\u3001\u52d5\u8108\u306e\u5f3e\u529b\u6027\u304c\u4f4e\u4e0b\u3057\u3001\u8840\u5727\u304c\u9ad8\u304f\u306a\u308a\u3084\u3059\u3044\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"6_%E5%91%BC%E5%90%B8%E5%99%A8%E3%81%AE%E7%97%87%E7%8A%B6%EF%BC%88%E6%9C%80%E3%82%82%E6%B3%A8%E6%84%8F%E3%81%8C%E5%BF%85%E8%A6%81%EF%BC%89\"><\/span><strong>6. \u547c\u5438\u5668\u306e\u75c7\u72b6\uff08\u6700\u3082\u6ce8\u610f\u304c\u5fc5\u8981\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u6c17\u9053\uff08\u7a7a\u6c17\u306e\u901a\u308a\u9053\uff09\u306b\u554f\u984c\u304c\u8d77\u304d\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5589\u982d\u30fb\u6c17\u7ba1\u306e\u72ed\u7a84<\/p>\n\n\n\n<p>\u9f3b\u3084\u53e3\u304b\u3089\u80ba\u3078\u7d9a\u304f\u7a7a\u6c17\u306e\u901a\u308a\u9053\uff08\u5589\u982d\u3084\u6c17\u7ba1\uff09\u304c\u72ed\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u7c98\u819c\u306e\u4e0b\u3067\u7dda\u7dad\u5316\u304c\u9032\u3080\u3053\u3068\u306b\u3088\u3063\u3066\u8d77\u3053\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3044\u3073\u304d\u304c\u3072\u3069\u3044\u3001\u606f\u3092\u3059\u308b\u6642\u306b\u30bc\u30fc\u30bc\u30fc\u3068\u3044\u3046\u97f3\u304c\u3059\u308b\u3001\u98a8\u90aa\u3092\u3072\u304f\u3068\u547c\u5438\u304c\u82e6\u3057\u304f\u306a\u308a\u3084\u3059\u3044\u3068\u3044\u3063\u305f\u75c7\u72b6\u304c\u898b\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u5168\u8eab\u9ebb\u9154\u306e\u969b\u306b\u4eba\u5de5\u547c\u5438\u5668\u306e\u7ba1\u3092\u5165\u308c\u308b\uff08\u633f\u7ba1\u3059\u308b\uff09\u64cd\u4f5c\u304c\u523a\u6fc0\u3068\u306a\u3063\u3066\u3001\u305d\u306e\u5f8c\u306b\u6c17\u7ba1\u304c\u72ed\u304f\u306a\u3063\u3066\u3057\u307e\u3046\u30ea\u30b9\u30af\u304c\u3042\u308b\u305f\u3081\u3001\u624b\u8853\u306e\u969b\u306b\u306f\u9ebb\u9154\u79d1\u533b\u3068\u306e\u5165\u5ff5\u306a\u76f8\u8ac7\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"7_%E3%81%9D%E3%81%AE%E4%BB%96%E3%81%AE%E7%97%87%E7%8A%B6\"><\/span><strong>7. \u305d\u306e\u4ed6\u306e\u75c7\u72b6<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u505c\u7559\u7cbe\u5de3<\/p>\n\n\n\n<p>\u7537\u306e\u5b50\u306e\u5834\u5408\u3001\u7cbe\u5de3\u304c\u9670\u56a2\u306e\u4e2d\u306b\u964d\u308a\u3066\u3053\u306a\u3044\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8996\u529b<\/p>\n\n\n\n<p>\u9060\u8996\u3001\u4e71\u8996\u3001\u659c\u8996\u306a\u3069\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n<!--nipt_mono-->\r\n<div class=\"nipt-mono\">\r\n    <div class=\"nipt-mono-btn\">\r\n        <a href=\"\/nipt\/nipt-mono\/\">\r\n            <img decoding=\"async\" loading=\"lazy\" src=\"\/nipt\/wp-content\/uploads\/2026\/03\/NIPT-MONO.webp\" alt=\"NIPT-MONO\u3067\u8abf\u3079\u3089\u308c\u307e\u3059\">\r\n         <\/a>\r\n    <\/div>\r\n<\/div>\r\n\r\n<style>\r\n.nipt-mono {\r\n    text-align: center; \/* \u89aa\u8981\u7d20\u3067\u6a2a\u4e2d\u592e *\/\r\n}\r\n.nipt-mono a img {\r\n    display: inline-block; \/* \u753b\u50cf\u3092\u30a4\u30f3\u30e9\u30a4\u30f3\u30d6\u30ed\u30c3\u30af\u5316\u3057\u3066 text-align \u306b\u53cd\u6620 *\/\r\n    width: 333px;\r\n}\r\n<\/style>\r\n<!--\/nipt_mono-->\r\n\r\n\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/32943450_s.webp\" alt=\"\u8d64\u3061\u3083\u3093\" class=\"wp-image-117048\"\/><\/figure><\/div>\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%8E%9F%E5%9B%A0\"><\/span><strong>\u539f\u56e0<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u306a\u305c\u3001\u7b4b\u8089\u304c\u3064\u3044\u305f\u308a\u3001\u4f53\u304c\u786c\u304f\u306a\u3063\u305f\u308a\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\u3002\u305d\u306e\u539f\u56e0\u306f\u3001\u7d30\u80de\u306b\u300c\u7d44\u7e54\u3092\u4f5c\u308c\u300d\u3068\u3044\u3046\u547d\u4ee4\u3092\u51fa\u3059\u4fe1\u53f7\u306e\u7570\u5e38\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"SMAD4%E9%81%BA%E4%BC%9D%E5%AD%90%E3%81%AE%E5%BD%B9%E5%89%B2\"><\/span><strong>SMAD4\u907a\u4f1d\u5b50\u306e\u5f79\u5272<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u539f\u56e0\u306f\u3001\u7b2c18\u756a\u67d3\u8272\u4f53\u306b\u3042\u308bSMAD4\uff08\u30b9\u30de\u30c3\u30c9\u30d5\u30a9\u30fc\uff09\u3068\u3044\u3046\u907a\u4f1d\u5b50\u306e\u5909\u7570\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u80de\u306e\u4e2d\u3067TGF-\u30d9\u30fc\u30bf\uff08\u30c6\u30a3\u30fc\u30b8\u30fc\u30a8\u30d5\u30fb\u30d9\u30fc\u30bf\uff09\u3068\u3044\u3046\u4fe1\u53f7\u4f1d\u9054\u7d4c\u8def\u306b\u304a\u3044\u3066\u50cd\u304f\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u4f5c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>TGF-\u30d9\u30fc\u30bf\u7d4c\u8def\u306f\u3001\u7d30\u80de\u306e\u5897\u6b96\u3001\u5206\u5316\u3001\u305d\u3057\u3066\u300c\u7d50\u5408\u7d44\u7e54\uff08\u30b3\u30e9\u30fc\u30b2\u30f3\u306a\u3069\uff09\u3092\u4f5c\u308b\u300d\u3068\u3044\u3046\u30d7\u30ed\u30bb\u30b9\u3092\u8abf\u7bc0\u3059\u308b\u975e\u5e38\u306b\u91cd\u8981\u306a\u30b7\u30b9\u30c6\u30e0\u3067\u3059\u3002<\/p>\n\n\n\n<p>SMAD4\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u7d30\u80de\u306e\u5916\u304b\u3089\u6765\u305f\u300c\u7d44\u7e54\u3092\u4f5c\u308c\u300d\u3068\u3044\u3046\u4fe1\u53f7\u3092\u53d7\u3051\u53d6\u308a\u3001\u305d\u308c\u3092\u7d30\u80de\u306e\u6838\u306e\u4e2d\u306b\u5c4a\u3051\u308b\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fc\u306e\u5f79\u5272\u3092\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%BD%95%E3%81%8C%E8%B5%B7%E3%81%8D%E3%81%A6%E3%81%84%E3%82%8B%E3%81%AE%E3%81%8B%EF%BC%88%E6%A9%9F%E8%83%BD%E7%8D%B2%E5%BE%97%E5%9E%8B%E5%A4%89%E7%95%B0%EF%BC%89\"><\/span><strong>\u4f55\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u304b\uff08\u6a5f\u80fd\u7372\u5f97\u578b\u5909\u7570\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>SMAD4\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u306f\u3001\u5927\u304d\u304f\u5206\u3051\u30662\u3064\u306e\u30bf\u30a4\u30d7\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u3064\u306f\u3001\u6a5f\u80fd\u304c\u5931\u308f\u308c\u3066\u3057\u307e\u3046\u30bf\u30a4\u30d7\u3067\u3001\u3053\u308c\u306f\u82e5\u5e74\u6027\u30dd\u30ea\u30dd\u30fc\u30b7\u30b9\u3068\u3044\u3046\u5927\u8178\u306b\u30dd\u30ea\u30fc\u30d7\u304c\u3067\u304d\u308b\u75c5\u6c17\u306e\u539f\u56e0\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3082\u3046\u4e00\u3064\u304c\u3001\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u539f\u56e0\u3068\u306a\u308b\u300c\u6a5f\u80fd\u7372\u5f97\u578b\u300d\u306e\u5909\u7570\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u3067\u306f\u3001SMAD4\u907a\u4f1d\u5b50\u306e\u7279\u5b9a\u306e\u5834\u6240\u306b\u5909\u7570\u304c\u8d77\u304d\u308b\u3053\u3068\u3067\u3001SMAD4\u30bf\u30f3\u30d1\u30af\u8cea\u304c\u901a\u5e38\u3088\u308a\u3082\u5b89\u5b9a\u3057\u3001\u50cd\u304d\u3059\u304e\u3066\u3057\u307e\u3046\u72b6\u614b\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u308f\u304b\u308a\u3084\u3059\u304f\u8a00\u3046\u3068\u3001\u300c\u7d44\u7e54\u3092\u4f5c\u308c\u300d\u300c\u4fee\u5fa9\u3057\u308d\u300d\u3068\u3044\u3046\u30b9\u30a4\u30c3\u30c1\u304c\u5165\u308a\u3063\u3071\u306a\u3057\u3001\u3042\u308b\u3044\u306f\u5f37\u304f\u5165\u308a\u3059\u304e\u3066\u3057\u307e\u3046\u72b6\u614b\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u305d\u306e\u7d50\u679c\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306a\u3069\u306e\u7d50\u5408\u7d44\u7e54\u304c\u904e\u5270\u306b\u4f5c\u3089\u308c\u3066\u3057\u307e\u3044\u3001\u76ae\u819a\u304c\u539a\u304f\u306a\u3063\u305f\u308a\u3001\u7b4b\u8089\u306e\u5468\u308a\u306e\u819c\u304c\u539a\u304f\u306a\u3063\u305f\u308a\u3001\u50b7\u8de1\u304c\u786c\u304f\u76db\u308a\u4e0a\u304c\u3063\u305f\u308a\uff08\u7dda\u7dad\u5316\uff09\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7b4b\u8089\u8cea\u306b\u898b\u3048\u308b\u306e\u3082\u3001\u7b4b\u8089\u305d\u306e\u3082\u306e\u304c\u5897\u3048\u3066\u3044\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u7b4b\u8089\u306e\u5468\u308a\u306e\u7d50\u5408\u7d44\u7e54\u304c\u5897\u3048\u3066\u3044\u308b\u5f71\u97ff\u3082\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E9%81%BA%E4%BC%9D%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6\"><\/span><strong>\u907a\u4f1d\u306b\u3064\u3044\u3066<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u3053\u306e\u75c5\u6c17\u306f\u5e38\u67d3\u8272\u4f53\u9855\u6027\u907a\u4f1d\u3001\u4ee5\u524d\u306f\u512a\u6027\u907a\u4f1d\u3068\u547c\u3070\u308c\u3066\u3044\u305f\u5f62\u5f0f\u3092\u3068\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4eba\u9593\u306f\u907a\u4f1d\u5b50\u30922\u672c\u30bb\u30c3\u30c8\u3067\u6301\u3063\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u3046\u3061\u306e\u7247\u65b9\u306eSMAD4\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308c\u3070\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u60a3\u8005\u3055\u3093\u306e\u307b\u3068\u3093\u3069\u306f\u3001\u3054\u4e21\u89aa\u304b\u3089\u907a\u4f1d\u3057\u305f\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3054\u4e21\u89aa\u306e\u907a\u4f1d\u5b50\u306f\u6b63\u5e38\u3067\u3001\u304a\u5b50\u3055\u3093\u306e\u4ee3\u3067\u521d\u3081\u3066\u907a\u4f1d\u5b50\u306e\u5909\u5316\u304c\u8d77\u3053\u308b\u65b0\u751f\u7a81\u7136\u5909\u7570\uff08de novo\u5909\u7570\uff09\u306e\u30b1\u30fc\u30b9\u304c\u5727\u5012\u7684\u306b\u591a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306f\u3001\u53d7\u7cbe\u5375\u304c\u3067\u304d\u308b\u904e\u7a0b\u3001\u3042\u308b\u3044\u306f\u7cbe\u5b50\u3084\u5375\u5b50\u304c\u3067\u304d\u308b\u904e\u7a0b\u3067\u5076\u7136\u306b\u8d77\u304d\u305f\u30b3\u30d4\u30fc\u30df\u30b9\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3042\u308a\u3001\u8ab0\u306e\u305b\u3044\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u598a\u5a20\u4e2d\u306e\u751f\u6d3b\u7fd2\u6163\u3084\u30b9\u30c8\u30ec\u30b9\u3001\u9ad8\u9f62\u51fa\u7523\u306a\u3069\u304c\u76f4\u63a5\u7684\u306a\u539f\u56e0\u3067\u8d77\u3053\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3057\u305f\u304c\u3063\u3066\u3001\u6b21\u306e\u304a\u5b50\u3055\u3093\u304c\u540c\u3058\u75c5\u6c17\u306b\u306a\u308b\u78ba\u7387\u306f\u3001\u4e00\u822c\u306e\u30ab\u30c3\u30d7\u30eb\u3068\u307b\u3068\u3093\u3069\u5909\u308f\u308a\u307e\u305b\u3093\uff08\u305f\u3060\u3057\u3001\u7a00\u306b\u6027\u817a<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/mosaicism\/\">\u30e2\u30b6\u30a4\u30af<\/a>\u3068\u3044\u3046\u73fe\u8c61\u304c\u3042\u308b\u305f\u3081\u3001\u5fc3\u914d\u306a\u5834\u5408\u306f\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3067\u306e\u76f8\u8ac7\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\uff09\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%A8%BA%E6%96%AD%E3%81%A8%E6%A4%9C%E6%9F%BB\"><\/span><strong>\u8a3a\u65ad\u3068\u691c\u67fb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u8a3a\u65ad\u306f\u3001\u7279\u5fb4\u7684\u306a\u75c7\u72b6\u306e\u89b3\u5bdf\u3068\u3001\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u306b\u3088\u3063\u3066\u78ba\u5b9a\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E8%87%A8%E5%BA%8A%E8%A8%BA%E6%96%AD\"><\/span><strong>1. \u81e8\u5e8a\u8a3a\u65ad<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u533b\u5e2b\u306f\u8a3a\u5bdf\u3067\u4ee5\u4e0b\u306e\u7279\u5fb4\u7684\u306a\u6240\u898b\u306e\u7d44\u307f\u5408\u308f\u305b\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u4f4e\u8eab\u9577\u3067\u7b4b\u8089\u8cea\u306a\u4f53\u683c\u3002<\/li>\n\n\n\n<li>\u76ae\u819a\u304c\u539a\u3044\u3002<\/li>\n\n\n\n<li>\u95a2\u7bc0\u306e\u52d5\u304d\u304c\u5236\u9650\u3055\u308c\u3066\u3044\u308b\u3002<\/li>\n\n\n\n<li>\u7279\u5fb4\u7684\u306a\u304a\u9854\u7acb\u3061\u3002<\/li>\n\n\n\n<li>\u96e3\u8074\u3084\u77e5\u7684\u767a\u9054\u306e\u9045\u308c\u3002<\/li>\n<\/ul>\n\n\n\n<p>\u3053\u308c\u3089\u306e\u7279\u5fb4\u304c\u63c3\u3063\u3066\u3044\u308b\u5834\u5408\u3001\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u304c\u5f37\u304f\u7591\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E9%81%BA%E4%BC%9D%E5%AD%A6%E7%9A%84%E6%A4%9C%E6%9F%BB\"><\/span><strong>2. \u907a\u4f1d\u5b66\u7684\u691c\u67fb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u78ba\u5b9a\u8a3a\u65ad\u306e\u305f\u3081\u306b\u6700\u3082\u91cd\u8981\u306a\u691c\u67fb\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u8840\u6db2\u3092\u63a1\u53d6\u3057\u3001DNA\u3092\u89e3\u6790\u3057\u3066SMAD4\u907a\u4f1d\u5b50\u306b\u5909\u7570\u304c\u3042\u308b\u304b\u3092\u8abf\u3079\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7279\u306b\u3001\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306b\u7279\u5fb4\u7684\u306a\u7279\u5b9a\u306e\u5834\u6240\uff08Ile500\u3084Arg496\u306a\u3069\uff09\u306b\u5909\u7570\u304c\u3042\u308b\u304b\u3092\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u306b\u3088\u308a\u3001\u4f3c\u305f\u3088\u3046\u306a\u75c7\u72b6\u3092\u6301\u3064\u4ed6\u306e\u7d50\u5408\u7d44\u7e54\u75be\u60a3\u3068\u533a\u5225\u3057\u3001\u8a3a\u65ad\u3092\u78ba\u5b9a\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E5%85%A8%E8%BA%AB%E3%81%AE%E8%A9%95%E4%BE%A1%E6%A4%9C%E6%9F%BB\"><\/span><strong>3. \u5168\u8eab\u306e\u8a55\u4fa1\u691c\u67fb<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u8a3a\u65ad\u304c\u3064\u3044\u305f\u5f8c\u306f\u3001\u5408\u4f75\u75c7\u304c\u306a\u3044\u304b\u5168\u8eab\u3092\u30c1\u30a7\u30c3\u30af\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5fc3\u30a8\u30b3\u30fc\u691c\u67fb\uff1a<\/strong> \u5fc3\u819c\u3084\u5fc3\u7b4b\u306e\u539a\u3055\u3001\u5f01\u306e\u52d5\u304d\u3001\u8840\u6d41\u306a\u3069\u3092\u8abf\u3079\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8074\u529b\u691c\u67fb\uff1a<\/strong> \u96e3\u8074\u306e\u7a2e\u985e\u3068\u7a0b\u5ea6\u3092\u8abf\u3079\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u547c\u5438\u6a5f\u80fd\u691c\u67fb\u30fb\u753b\u50cf\u691c\u67fb\uff1a<\/strong> \u5589\u3084\u6c17\u7ba1\u306e\u72ed\u7a84\u304c\u306a\u3044\u304b\u3001CT\u3084MRI\u3067\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u5185\u8996\u93e1\u691c\u67fb\u306a\u3069\u306f\u523a\u6fc0\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u614e\u91cd\u306b\u5224\u65ad\u3055\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u773c\u79d1\u691c\u67fb\uff1a<\/strong> \u8996\u529b\u3084\u76ee\u306e\u69cb\u9020\u3092\u8abf\u3079\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6574\u5f62\u5916\u79d1\u7684\u691c\u67fb\uff1a<\/strong> \u95a2\u7bc0\u306e\u53ef\u52d5\u57df\u3084\u9aa8\u306e\u5909\u5f62\u3092\u30ec\u30f3\u30c8\u30b2\u30f3\u306a\u3069\u3067\u78ba\u8a8d\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%99%82%E3%81%A8%E7%AE%A1%E7%90%86\"><\/span><strong>\u6cbb\u7642\u3068\u7ba1\u7406<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u73fe\u5728\u306e\u533b\u5b66\u3067\u306f\u3001\u907a\u4f1d\u5b50\u3092\u4fee\u5fa9\u3057\u3066\u75c5\u6c17\u3092\u6839\u672c\u304b\u3089\u6cbb\u3059\u6cbb\u7642\u6cd5\u306f\u307e\u3060\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u3057\u304b\u3057\u3001\u305d\u308c\u305e\u308c\u306e\u75c7\u72b6\u306b\u5bfe\u3057\u3066\u9069\u5207\u306a\u7ba1\u7406\u3092\u884c\u3044\u3001\u7279\u306b\u300c\u7dda\u7dad\u5316\u306e\u30ea\u30b9\u30af\u300d\u3092\u907f\u3051\u308b\u3053\u3068\u3067\u3001\u5065\u5eb7\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u306f\u5341\u5206\u306b\u53ef\u80fd\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u6cbb\u7642\u306e\u76ee\u6a19\u306f\u3001\u5408\u4f75\u75c7\u3092\u4e88\u9632\u3057\u3001\u751f\u6d3b\u306e\u8cea\uff08QOL\uff09\u3092\u9ad8\u3081\u308b\u3053\u3068\u306b\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"1_%E3%80%8C%E7%B7%9A%E7%B6%AD%E5%8C%96%E3%80%8D%E3%82%92%E9%98%B2%E3%81%90%E3%81%9F%E3%82%81%E3%81%AE%E6%9C%80%E9%87%8D%E8%A6%81%E4%BA%8B%E9%A0%85\"><\/span><strong>1. \u300c\u7dda\u7dad\u5316\u300d\u3092\u9632\u3050\u305f\u3081\u306e\u6700\u91cd\u8981\u4e8b\u9805<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u7ba1\u7406\u306b\u304a\u3044\u3066\u3001\u6700\u3082\u6c17\u3092\u3064\u3051\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u306e\u304c\u3001\u533b\u7642\u51e6\u7f6e\u306b\u3088\u308b\u4fb5\u8972\uff08\u4f53\u3078\u306e\u30c0\u30e1\u30fc\u30b8\uff09\u3092\u6700\u5c0f\u9650\u306b\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u624b\u8853\u3068\u9ebb\u9154\u306e\u6ce8\u610f\u70b9<\/p>\n\n\n\n<p>\u624b\u8853\u304c\u5fc5\u8981\u306a\u5834\u5408\uff08\u4f8b\u3048\u3070\u505c\u7559\u7cbe\u5de3\u306e\u624b\u8853\u3084\u3001\u305d\u306e\u4ed6\u306e\u5916\u79d1\u624b\u8853\uff09\u3001\u6c17\u7ba1\u633f\u7ba1\uff08\u5589\u306b\u7ba1\u3092\u5165\u308c\u308b\u3053\u3068\uff09\u306f\u53ef\u80fd\u306a\u9650\u308a\u907f\u3051\u308b\u3001\u3042\u308b\u3044\u306f\u6975\u3081\u3066\u614e\u91cd\u306b\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7ba1\u306e\u523a\u6fc0\u306b\u3088\u3063\u3066\u3001\u8853\u5f8c\u306b\u5589\u3084\u6c17\u7ba1\u304c\u816b\u308c\u305f\u308a\u3001\u72ed\u304f\u306a\u3063\u305f\u308a\u3059\u308b\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305f\u3081\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u9ebb\u9154\u79d1\u533b\u3084\u5916\u79d1\u533b\u306b\u5bfe\u3057\u3001\u300c\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u3067\u3042\u308a\u3001\u6c17\u9053\u72ed\u7a84\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u300d\u3053\u3068\u3092\u4e8b\u524d\u306b\u3057\u3063\u304b\u308a\u3068\u4f1d\u3048\u3001\u3069\u3046\u3057\u3066\u3082\u5fc5\u8981\u306a\u5834\u5408\u4ee5\u5916\u306f\u6c17\u7ba1\u633f\u7ba1\u3092\u907f\u3051\u305f\u9ebb\u9154\u65b9\u6cd5\uff08\u30de\u30b9\u30af\u63db\u6c17\u3084\u30e9\u30ea\u30f3\u30b8\u30a2\u30eb\u30de\u30b9\u30af\u306a\u3069\uff09\u3092\u691c\u8a0e\u3057\u3066\u3082\u3089\u3046\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5185\u8996\u93e1\u691c\u67fb\u306e\u5236\u9650<\/p>\n\n\n\n<p>\u6c17\u7ba1\u652f\u93e1\u3084\u80c3\u30ab\u30e1\u30e9\u306a\u3069\u306e\u5185\u8996\u93e1\u691c\u67fb\u3082\u3001\u7c98\u819c\u3092\u523a\u6fc0\u3057\u3066\u7dda\u7dad\u5316\u3092\u8a98\u767a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u672c\u5f53\u306b\u5fc5\u8981\u306a\u5834\u5408\u306b\u9650\u308a\u3001\u611b\u8b77\u7684\u306b\uff08\u512a\u3057\u304f\uff09\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"2_%E8%96%AC%E7%89%A9%E7%99%82%E6%B3%95%E3%81%AE%E5%8F%AF%E8%83%BD%E6%80%A7\"><\/span><strong>2. \u85ac\u7269\u7642\u6cd5\u306e\u53ef\u80fd\u6027<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u73fe\u5728\u3001\u30ed\u30b5\u30eb\u30bf\u30f3\u3068\u3044\u3046\u9ad8\u8840\u5727\u306e\u85ac\u304c\u3001TGF-\u30d9\u30fc\u30bf\u306e\u50cd\u304d\u3092\u6291\u3048\u308b\u4f5c\u7528\u3092\u6301\u3064\u3053\u3068\u304b\u3089\u3001\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\u306e\u7dda\u7dad\u5316\u4e88\u9632\u3084\u6cbb\u7642\u306b\u52b9\u679c\u304c\u3042\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u671f\u5f85\u3055\u308c\u3001\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4e00\u90e8\u306e\u60a3\u8005\u3055\u3093\u3067\u306f\u5b9f\u969b\u306b\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u307e\u3060\u78ba\u7acb\u3055\u308c\u305f\u6a19\u6e96\u6cbb\u7642\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4e3b\u6cbb\u533b\u3068\u3088\u304f\u76f8\u8ac7\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"3_%E3%83%AA%E3%83%8F%E3%83%93%E3%83%AA%E3%83%86%E3%83%BC%E3%82%B7%E3%83%A7%E3%83%B3%EF%BC%88%E7%99%82%E8%82%B2%EF%BC%89\"><\/span><strong>3. \u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\uff08\u7642\u80b2\uff09<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u95a2\u7bc0\u306e\u786c\u3055\u3084\u767a\u9054\u306e\u9045\u308c\u306b\u5bfe\u3057\u3066\u3001\u7d99\u7d9a\u7684\u306a\u30ea\u30cf\u30d3\u30ea\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7406\u5b66\u7642\u6cd5\uff08PT\uff09<\/p>\n\n\n\n<p>\u95a2\u7bc0\u304c\u56fa\u307e\u3089\u306a\u3044\u3088\u3046\u306b\u3001\u611b\u8b77\u7684\u306a\u30b9\u30c8\u30ec\u30c3\u30c1\u3092\u884c\u3044\u307e\u3059\u3002\u7121\u7406\u306b\u5f37\u304f\u4f38\u3070\u3059\u3068\u9006\u306b\u7d44\u7e54\u3092\u50b7\u3081\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u300c\u512a\u3057\u304f\u3001\u3086\u3063\u304f\u308a\u300d\u304c\u57fa\u672c\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4f53\u306e\u4f7f\u3044\u65b9\u306e\u7df4\u7fd2\u3084\u3001\u59ff\u52e2\u306e\u4fdd\u6301\u306a\u3069\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f5c\u696d\u7642\u6cd5\uff08OT\uff09<\/p>\n\n\n\n<p>\u624b\u5148\u306e\u786c\u3055\u304c\u3042\u3063\u3066\u3082\u4f7f\u3044\u3084\u3059\u3044\u9053\u5177\uff08\u592a\u3044\u67c4\u306e\u30b9\u30d7\u30fc\u30f3\u306a\u3069\uff09\u3092\u63d0\u6848\u3057\u305f\u308a\u3001\u65e5\u5e38\u751f\u6d3b\u52d5\u4f5c\u306e\u7df4\u7fd2\u3092\u884c\u3063\u305f\u308a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8a00\u8a9e\u8074\u899a\u7642\u6cd5\uff08ST\uff09<\/p>\n\n\n\n<p>\u96e3\u8074\u3084\u77e5\u7684\u767a\u9054\u306e\u9045\u308c\u306b\u3088\u308b\u8a00\u8449\u306e\u554f\u984c\u306b\u5bfe\u3057\u3001\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u306e\u7df4\u7fd2\u3092\u884c\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u88dc\u8074\u5668\u306e\u8abf\u6574\u3084\u88c5\u7528\u7df4\u7fd2\u3082\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"4_%E8%81%B4%E8%A6%9A%E3%81%AE%E7%AE%A1%E7%90%86\"><\/span><strong>4. \u8074\u899a\u306e\u7ba1\u7406<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u96e3\u8074\u306b\u5bfe\u3057\u3066\u306f\u3001\u88dc\u8074\u5668\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u8a00\u8449\u306e\u805e\u304d\u53d6\u308a\u3084\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u3092\u52a9\u3051\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4f1d\u97f3\u6027\u96e3\u8074\u3068\u611f\u97f3\u6027\u96e3\u8074\u306e\u4e21\u65b9\u304c\u3042\u308b\u5834\u5408\u304c\u591a\u3044\u305f\u3081\u3001\u8033\u9f3b\u79d1\u533b\u306b\u3088\u308b\u5b9a\u671f\u7684\u306a\u30c1\u30a7\u30c3\u30af\u3068\u8abf\u6574\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"5_%E5%BE%AA%E7%92%B0%E5%99%A8%E3%83%BB%E5%91%BC%E5%90%B8%E5%99%A8%E3%81%AE%E5%AE%9A%E6%9C%9F%E6%A4%9C%E8%A8%BA\"><\/span><strong>5. \u5faa\u74b0\u5668\u30fb\u547c\u5438\u5668\u306e\u5b9a\u671f\u691c\u8a3a<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u75c7\u72b6\u304c\u306a\u304f\u3066\u3082\u3001\u5e74\u306b1\u56de\u7a0b\u5ea6\u306f\u5fc3\u30a8\u30b3\u30fc\u691c\u67fb\u306a\u3069\u3067\u5fc3\u81d3\u306e\u72b6\u614b\u3092\u30c1\u30a7\u30c3\u30af\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u547c\u5438\u306e\u72b6\u614b\uff08\u3044\u3073\u304d\u3084\u606f\u82e6\u3057\u3055\uff09\u306b\u5909\u5316\u304c\u306a\u3044\u304b\u3001\u65e5\u9803\u304b\u3089\u6ce8\u610f\u6df1\u304f\u89b3\u5bdf\u3057\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%81%BE%E3%81%A8%E3%82%81\"><\/span><strong>\u307e\u3068\u3081<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30de\u30a4\u30e4\u30fc\u75c7\u5019\u7fa4\uff08Myhre Syndrome\uff09\u306b\u3064\u3044\u3066\u306e\u89e3\u8aac\u3092\u307e\u3068\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u75c5\u6c17\u306e\u672c\u8cea\uff1a<\/strong> SMAD4\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3088\u308a\u3001\u7d44\u7e54\u3092\u4f5c\u308b\u30b9\u30a4\u30c3\u30c1\u304c\u5165\u308a\u3059\u304e\u3066\u3044\u308b\u72b6\u614b\u306b\u306a\u308a\u3001\u7d50\u5408\u7d44\u7e54\u304c\u539a\u304f\u786c\u304f\u306a\u308b\u5148\u5929\u6027\u306e\u75be\u60a3\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u4e3b\u306a\u7279\u5fb4\uff1a<\/strong> \u4f4e\u8eab\u9577\u3001\u7b4b\u8089\u8cea\u306a\u4f53\u683c\u3001\u95a2\u7bc0\u306e\u52d5\u304b\u3057\u306b\u304f\u3055\u3001\u96e3\u8074\u3001\u77e5\u7684\u767a\u9054\u306e\u9045\u308c\u306a\u3069\u304c\u7279\u5fb4\u3067\u3059\u3002<\/li>\n\n\n\n<li><strong>\u6700\u5927\u306e\u6ce8\u610f\u70b9\uff1a<\/strong> \u4f53\u304c\u50b7\u3092\u6cbb\u305d\u3046\u3068\u3059\u308b\u529b\u304c\u5f37\u3059\u304e\u308b\u305f\u3081\u3001\u624b\u8853\u3084\u6c17\u7ba1\u633f\u7ba1\u306a\u3069\u306e\u523a\u6fc0\u306b\u3088\u3063\u3066\u7d44\u7e54\u304c\u72ed\u304f\u306a\u3063\u305f\u308a\u786c\u304f\u306a\u3063\u305f\u308a\u3059\u308b\u300c\u7dda\u7dad\u5316\u300d\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u533b\u7642\u9023\u643a\u306e\u91cd\u8981\u6027\uff1a<\/strong> \u624b\u8853\u3084\u691c\u67fb\u306e\u969b\u306f\u3001\u533b\u5e2b\u306b\u75c5\u6c17\u306e\u7279\u5fb4\uff08\u7279\u306b\u6c17\u9053\u306e\u30ea\u30b9\u30af\uff09\u3092\u6b63\u3057\u304f\u4f1d\u3048\u308b\u3053\u3068\u304c\u3001\u5b89\u5168\u3092\u5b88\u308b\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u539f\u56e0\uff1a<\/strong> \u307b\u3068\u3093\u3069\u304c\u7a81\u7136\u5909\u7570\u306b\u3088\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u89aa\u306e\u305b\u3044\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/li>\n<\/ul>\n\n\n<!--nipt_mono-->\r\n<div class=\"nipt-mono\">\r\n    <div class=\"nipt-mono-btn\">\r\n        <a href=\"\/nipt\/nipt-mono\/\">\r\n            <img decoding=\"async\" loading=\"lazy\" src=\"\/nipt\/wp-content\/uploads\/2026\/03\/NIPT-MONO.webp\" alt=\"NIPT-MONO\u3067\u8abf\u3079\u3089\u308c\u307e\u3059\">\r\n         <\/a>\r\n    <\/div>\r\n<\/div>\r\n\r\n<style>\r\n.nipt-mono {\r\n    text-align: center; \/* 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href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/myhre-syndrome-guide\/\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":122,"featured_media":115876,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1392],"tags":[],"class_list":["post-122683","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1392"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/122683","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/122"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=122683"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/122683\/revisions"}],"predecessor-version":[{"id":126321,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/122683\/revisions\/126321"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/115876"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=122683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=122683"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=122683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}