{"id":45619,"date":"2020-12-09T11:05:48","date_gmt":"2020-12-09T02:05:48","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/"},"modified":"2024-12-02T13:03:29","modified_gmt":"2024-12-02T04:03:29","slug":"bhatt-2019-uog-v2-performance","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/?lang=zh-hans","title":{"rendered":"\u901a\u8fc7VeriSeq\u2122 NIPT Solution v2\uff0c\u57fa\u4e8e\u5168\u57fa\u56e0\u7ec4\u65e0PCR\u7684\u6027\u80fd\u548c\u6210\u5bf9\u672b\u7aef\u6d4b\u5e8f\u7684\u975e\u4fb5\u5165\u6027\u4ea7\u524d\u7b5b\u67e5\u68c0\u6d4b"},"content":{"rendered":"\n<p>S. Bhatt<sup>1<\/sup>, N. Flowers<sup>2<\/sup>, D. Vavrek<sup>1<\/sup>, K. Meier<sup>1<\/sup>, T. Kalista<sup>1<\/sup>, C. Deciu<sup>1<\/sup>, S. Duenwald<sup>1<\/sup>, M.D. Pertile<sup>3<\/sup><\/p>\n\n\n\n<p><sup>1<\/sup>Illumina, Inc, San Diego, CA, USA; <sup>2<\/sup>Victorian Clinical Genetics Services, Parkville, VIC, Australia; <sup>3<\/sup><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>, Victorian Clinical Genetics Services, Melbourne, VIC, Australia<\/p>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/?lang=zh-hans\/#%E7%9B%AE%E6%A0%87%E3%80%82\" >\u76ee\u6807\u3002<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/?lang=zh-hans\/#%E6%96%B9%E6%B3%95\" >\u65b9\u6cd5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/?lang=zh-hans\/#%E7%B5%90%E5%B1%80\" >\u7d50\u5c40<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/?lang=zh-hans\/#%E7%BB%93%E8%AE%BA\" >\u7ed3\u8bba<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%9B%AE%E6%A0%87%E3%80%82\"><\/span>\u76ee\u6807\u3002<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u5728\u68c0\u6d4b\u5305\u62ec\u90e8\u5206\u7f3a\u5931\u548c\u91cd\u590d\u5168\u57fa\u56e0\u7ec4\u7684\u80ce\u513f\u67d3\u8272\u4f53\u5f02\u5e38\u4e2d\uff0c\u57fa\u4e8e\u65e0\u7ec6\u80deDNA\u7684\u975e\u4fb5\u5165\u6027\u4ea7\u524d\u68c0\u6d4b(<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>)\uff0c\u8bc4\u4f30VeriSeq\u2122 NIPTSolutiov2\u7684\u9ad8\u5ea6\u81ea\u52a8\u5316\u7684\u65e0PCR\u6eb6\u6db2\u7684\u6027\u80fd\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%96%B9%E6%B3%95\"><\/span>\u65b9\u6cd5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u4f7f\u7528VeriSeq\u2122 <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> Solution v2\u5bf9\u598a\u5a20\u81f3\u5c1110\u5468\u4ee5\u4e0a\u7684\u5b55\u5987\u7684\u91c7\u8840\u51b7\u51bb\u8840\u6d46\u6837\u672c\u8fdb\u884c\u4e86\u68c0\u6d4b\u3002VeriSeq\u2122 <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> Solution v2\u67092\u4e2a\u62a5\u544a\u9009\u9879\uff1a\u57fa\u672c\u5206\u6790\u548c\u5168\u57fa\u56e0\u7ec4\u5206\u6790\u3002\u672c\u6587\u4ecb\u7ecd\u4e86\u5173\u4e8e\u62a5\u544a\u5e38\u89c1\u7684\u4e09\u4f53\u3001\u6027\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u548c\u80ce\u513f\u6027\u522b\u3001\u7f55\u89c1\u7684\u5e38\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\uff0c\u4ee5\u53ca7 Mb\u4ee5\u4e0a\u7684\u90e8\u5206\u7f3a\u5931\u548c\u91cd\u590d\u7684\u5168\u57fa\u56e0\u7ec4\u5206\u6790\u3002 \u5bf9\u4e8e\u6240\u6709\u75c5\u4f8b\uff0c\u90fd\u6709\u57fa\u4e8e\u7ec6\u80de\u9057\u4f20\u5b66\u7ed3\u679c\u6216\u65b0\u751f\u513f\u4f53\u68c0\u7684\u4e34\u5e8a\u7ed3\u679c\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%B5%90%E5%B1%80\"><\/span>\u7d50\u5c40<span 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\u5305\u62ec\u5d4c\u5408\u5f0f\u7684\u7279\u5f02\u6027\u4e3a\u300121\u4e09\u4f53\u7efc\u5408\u75c799.90%(1987\/1989)\uff0c\u7279\u5f02\u6027\u4e3a99.31%(1954\/1967)\uff0c\u4f30\u8ba1\u503c\u4e0e\u4e0d\u5305\u62ec\u5d4c\u5408\u5f0f\u7684\u60c5\u51b5\u76f8\u5f53\u3002 \u5728\u8fd9\u4e2a\u961f\u5217\u4e2d\uff0c\u60a3\u670921\u4e09\u4f53\u7efc\u5408\u75c7\u7684\u53cc\u80de\u80ce\u67097\u4f8b\uff0c\u6240\u6709\u75c5\u4f8b\u90fd\u68c0\u6d4b\u523021\u53f7\u67d3\u8272\u4f53\u5f02\u5e38\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%BB%93%E8%AE%BA\"><\/span>\u7ed3\u8bba<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u57fa\u4e8e\u53cc\u7aef\u6d4b\u5e8f\u7684VeriSeq\u2122 <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a> Solution v2\uff0c\u5177\u6709\u57fa\u672c\u548c\u5168\u57fa\u56e0\u7ec4\u62a5\u544a\u9009\u9879\uff0c\u663e\u793a\u51fa\u9ad8\u7075\u654f\u5ea6\u548c\u9ad8\u7279\u5f02\u6027\uff0c\u5e76\u4e14\u5931\u8d25\u7387\u4f4e\u3002<br>\u91cd\u8981\u7684\u662f\uff0c\u5bf9\u6240\u6709\u5f02\u5e3898.3%\u7684\u7279\u5f02\u6027\u8fdc\u8fdc\u9ad8\u4e8e\u901a\u8fc7\u8840\u6e05\u7b5b\u67e5\u768421\u4e09\u4f53\u7efc\u5408\u75c7\u768495%\u7279\u5f02\u6027\u3002 \u56e0\u6b64\uff0c\u8fd9\u79cd\u5168\u57fa\u56e0\u7ec4\u7684NIPT\u7684\u62a5\u544a\u65b9\u6cd5\u5c06\u5bfc\u81f4\u67d3\u8272\u4f53\u7684\u6bd4\u4f8b\u589e\u52a0\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"S. Bhatt1, N. Flower&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/bhatt-2019-uog-v2-performance\/?lang=zh-hans\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":1,"featured_media":898,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[251],"tags":[319,318,320,211],"class_list":["post-45619","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-treatise-zh-hans","tag-319","tag-nipt","tag-320","tag-veriseq"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/45619","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=45619"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/45619\/revisions"}],"predecessor-version":[{"id":84715,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/45619\/revisions\/84715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/898"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=45619"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=45619"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=45619"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}