{"id":72747,"date":"2021-04-21T18:49:33","date_gmt":"2021-04-21T09:49:33","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/"},"modified":"2024-03-12T14:05:07","modified_gmt":"2024-03-12T05:05:07","slug":"xlinked-recessive-inheritance","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en","title":{"rendered":"Don&#8217;t Ignore the Risk of Genetic Disease~Test Your Baby&#8217;s Gender [Doctor Supervised]."},"content":{"rendered":"\n<p><div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\"><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_83 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Summary_of_this_article\" >Summary of this article<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Why_find_out_the_sex_of_your_baby_before_birth\" >Why find out the sex of your baby before birth?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Diseases_prone_to_companion_recessive_inheritance\" >Diseases prone to companion recessive inheritance<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#red-green_color-blindness\" >red-green color-blindness<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Hemophilia_A_and_B\" >Hemophilia (A and B)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#muscular_dystrophy\" >muscular dystrophy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#XLA_X-linked_non-gammaglobulinemia\" >XLA (X-linked non-gammaglobulinemia)<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#X-linked_ichthyosis\" >X-linked ichthyosis<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Glucose-6-phosphate_dehydrogenase_deficiency\" >Glucose-6-phosphate dehydrogenase deficiency<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Companion_recessive_inheritance_is_the_cause_of_the_disease_and_is_inherited\" >Companion recessive inheritance is the cause of the disease and is inherited<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Human_gender_is_represented_by_X_and_Y\" >Human gender is represented by X and Y<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Part_of_X_is_abnormal_and_will_be_passed_on\" >Part of X is abnormal and will be passed on<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Son_has_onset_of_disease_daughter_rarely_has_onset_of_disease\" >Son has onset of disease, daughter rarely has onset of disease<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#Both_daughters_and_sons_inherit\" >Both daughters and sons inherit<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\/#What_you_as_a_parent_can_do_for_your_baby_before_birth_full_chromosome_test\" >What you, as a parent, can do for your baby before birth [full chromosome test].<\/a><\/li><\/ul><\/nav><\/div>\n<h2 style=\"margin-top:1rem;\"><span class=\"ez-toc-section\" id=\"Summary_of_this_article\"><\/span>Summary of this article<span class=\"ez-toc-section-end\"><\/span><\/h2><p>It is advisable to find out the sex and genetic makeup of your baby before birth because some genetic diseases have a risk of developing depending on the sex of the baby. Understanding genetic diseases will help you as a parent to make the right decisions and raise your child properly. It will also help you as a parent to make your baby&#8217;s life more comfortable without being confused by the sudden onset of the disease.<\/p><\/div><\/p>\n\n\n\n<div class=\"toc\">\n<ul>\n<li><a href=\"#c1\">Why find out the sex of your baby before birth?<\/a><\/li><li><a href=\"#c2\">Diseases prone to companion recessive inheritance<\/a>\n    <ul>\n      <li><a href=\"#c2-1\">red-green color-blindness<\/a><\/li>\n      <li><a href=\"#c2-2\">haemophilia<\/a><\/li>\n      <li><a href=\"#c2-3\">muscular dystrophy<\/a><\/li>\n      <li><a href=\"#c2-4\">XLA (X-linked non-gammaglobulinemia)<\/a><\/li>\n      <li><a href=\"#c2-5\">X-linked ichthyosis<\/a><\/li>\n      <li><a href=\"#c2-6\">Glucose-6-phosphate dehydrogenase deficiency<\/a><\/li>\n    <\/ul>\n  <\/li><li><a href=\"#c3\">Companion recessive inheritance is the cause of the disease and is inherited<\/a>\n    <ul>\n      <li><a href=\"#c3-1\">Human gender is represented by X and Y<\/a><\/li>\n      <li><a href=\"#c3-2\">Part of X is abnormal and will be passed on<\/a><\/li>\n      <li><a href=\"#c3-3\">Son has onset of disease, daughter rarely has onset of disease<\/a><\/li>\n      <li><a href=\"#c3-4\">Both daughters and sons inherit<\/a>\n        <ul>\n          <li><a href=\"#c3-4-1\">If the father has an abnormal X chromosome<\/a><\/li>\n          <li><a href=\"#c3-4-2\">If the mother has an abnormal X chromosome<\/a><\/li>\n        <\/ul>\n      <\/li>\n    <\/ul>\n  <\/li><li><a href=\"#c4\">What you, as a parent, can do for your baby before birth [full chromosome test].<\/a><\/li>\n<\/ul>\n  <button class=\"toc_more\">Open Table of Contents<\/button>\n<\/div>\n\n\n<p style=\"width:100%;max-width:300px;margin:0 auto;\"><a href=\"\/nipt\/\" class=\"content-bnr about\"><img decoding=\"async\" src=\"\/nipt\/wp-content\/themes\/hiro_nipt\/img\/banner\/nipt04pc.png\" alt=\"\u80ce\u5150\u306e\u6027\u5225\u306f10\u9031\u76ee\u3067\u308f\u304b\u308b\"><\/a> <\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"c1\"><span class=\"ez-toc-section\" id=\"Why_find_out_the_sex_of_your_baby_before_birth\"><\/span>Why find out the sex of your baby before birth?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>What&#8217;s the point of finding out the sex before birth?&#8221;<br>It&#8217;s going to be less fun.&#8221;<br>Do you have these thoughts about the sex of your baby?<\/p>\n\n\n\n<p>To sum up, it is better to find out the sex and genetic makeup of the baby before delivery.<br>This is because some genetic diseases have a risk of developing*1 depending on gender.<\/p>\n\n\n\n<p>If we know the gender and genetic information before the birth, we can provide for the comfort of the baby as parents.<\/p>\n\n\n\n<p>X-linked recessive inheritance (X-linked recessive inheritance) is one of the causes of genetic disease.<br>Boys with a companion recessive inheritance develop the disease.<br>If it is a girl, your grandchildren may be at risk for developing the disease.<\/p>\n\n\n\n<p>In this article,<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Diseases caused by companion recessive inheritance<\/li>\n\n\n\n<li>About Accompanied Recessive Inheritance<\/li>\n\n\n\n<li>What tests should I do as a parent?<br><\/li>\n<\/ul>\n\n\n\n<p>This section explains the<\/p>\n\n\n\n<p>If you do not understand the above, you will not be able to do anything to help your baby before the onset of the disease.<br>Even after the onset of the disease, they do not know when to go to the hospital, and by the time they realize it, it is too late.<br>Without knowledge about the disease, it is hard to know what department to go to.<\/p>\n\n\n\n<p>However, understanding genetic diseases can help you as a parent make appropriate decisions and raise your child.<br>It will help you, as a parent, to make your baby&#8217;s life more comfortable without being confused by the sudden onset of the disease.<\/p>\n\n\n\n<p>1 Onset: Symptoms or illness.<br>In this article, companion recessive inheritance is the cause of the disease.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"600\" height=\"370\" src=\"\/nipt\/wp-content\/uploads\/2021\/12\/ca994bd45fc2f4275370a12ff8aa9034.jpg\" alt=\"Why find out the sex of your baby before birth?\" class=\"wp-image-21377\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"c2\"><span class=\"ez-toc-section\" id=\"Diseases_prone_to_companion_recessive_inheritance\"><\/span>Diseases prone to companion recessive inheritance<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>Humans have an X chromosome, and the information that makes up the human body is recorded in the X chromosome, and this information is called genes.<\/p>\n\n\n\n<p>However, when this information is rewritten due to an abnormality, humans go on to various diseases.<\/p>\n\n\n\n<p>The type of disease depends on which part of the disease is rewritten.<br><br>And if you or your spouse has any of the diseases listed below, your baby may inherit them.<\/p>\n\n\n\n    <a href=\"\/nipt\/congenital-disease\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u5148\u5929\u6027\u75be\u60a3\u3068\u306f\uff1f\u3010\u533b\u5e2b\u76e3\u4fee\u3011 <\/div>\n          <div class=\"blog-card-excerpt\">\u5148\u5929\u6027\u75be\u60a3\u306f\u751f\u307e\u308c\u305f\u3068\u304d\u306e\u4f53\u306e\u5f62\u3084\u81d3\u5668\u306e\u6a5f\u80fd\u306b\u7570\u5e38\u304c\u3042\u308b\u75be\u60a3\u306e\u3053\u3068\u3092\u6307\u3057\u307e\u3059\u3002\u67d3\u8272\u4f53\u3084\u907a\u4f1d\u5b50\u306e\u7570\u5e38\u3001\u85ac\u5264\u3084\u611f\u67d3\u75c7\u306a\u3069\u69d8\u3005\u306a\u539f\u56e0\u306b\u3088\u308a\u8d77\u3053\u308b\u3053...<\/div>\n      <\/div>\n    <\/a>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c2-1\"><span class=\"ez-toc-section\" id=\"red-green_color-blindness\"><\/span>red-green color-blindness<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Simply put, they cannot recognize red and green systems.<br>I do not have bad eyesight.<br>However, there are restrictions on the occupations that can be entered in the future.<br><br>It is a type of color blindness, known as color blindness (shikimou).<\/p>\n\n\n\n<p>for example<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Traffic and transportation pilots who see signal lights<\/li>\n\n\n\n<li>Painter, Designer<\/li>\n\n\n\n<li>Police, Fire, Marine, Defense<\/li>\n\n\n\n<li>Fugu Chef, Poisonous and Deleterious Substance Control Supervisor<\/li>\n<\/ul>\n\n\n\n<p>is a profession that requires proof of non colorblindness.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c2-2\"><span class=\"ez-toc-section\" id=\"Hemophilia_A_and_B\"><\/span>Hemophilia (A and B)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Hemophilia is a disease in which &#8220;when you bleed, you can&#8217;t stop bleeding.&#8221;<br>This is because blood clotting factors are low.<br><br>Blood coagulation factors are responsible for blood clotting.<br>When blood is drawn from an injury, it hardens and forms a &#8220;scab&#8221; thanks to blood clotting factors.<\/p>\n\n\n\n<p>There are two types of hemophilia, A and B, which develop from a companion recessive inheritance.<br>The difference between hemophilia A and B is the difference in blood clotting factors.<br>In other words, which blood clotting factors are low?<\/p>\n\n\n\n<p>There is more than one blood coagulation factor.<\/p>\n\n\n\n<p>Hemophilia A is due to abnormalities of factor VIII (8) and hemophilia B is due to abnormalities of factor IX (9).<br><\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c2-3\"><span class=\"ez-toc-section\" id=\"muscular_dystrophy\"><\/span>muscular dystrophy<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>It is a disease that causes loss of muscle control.<br>The reason for the loss of muscle control is the lack of dystrophin.<br>Dystrophin is a protein that supports muscle shape from the inside out.<br>When the dystrophin gene is abnormal, dystrophin is not produced by the body.<\/p>\n\n\n\n<p><br>The severity of the disease depends on which muscles lose control.<br>For example, respiratory muscles can lead to death from respiratory failure.<br>Without control of the legs and pelvic area, the patient will not be able to walk and will be in a wheelchair.<br>In recent years, the disease became famous with the movie &#8220;Banana Kayo Konnichiwa Aishiki Jitsuwa&#8221; starring Yo Oizumi.<\/p>\n\n\n\n<h4 id=\"c2-3-1\">Becker and Duchenne types<\/h4>\n\n\n\n<p>There are two types of muscular dystrophy caused by companion recessive inheritance: the Becker and Duchenne types.<br>The difference between the two is the amount of dystrophin.<br>Compared to the Becker type, the Duchenne type has a smaller amount of dystrophin.<\/p>\n\n\n\n<p>Life expectancy also varies, with the Duchenne type surviving to around 30 years of age and the Becker type surviving into their 40s in some cases.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c2-4\"><span class=\"ez-toc-section\" id=\"XLA_X-linked_non-gammaglobulinemia\"><\/span>XLA (X-linked non-gammaglobulinemia)<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>XLA (X-linked non-gammaglobulinemia) makes the patient more susceptible to infection.<\/p>\n\n\n\n<p>The reason for the increased susceptibility to infection is that B cells are not produced, leading to a weakened immune system.<\/p>\n\n\n\n<p>The role of B cells is to produce antibodies.<br>B cells are not alone in immune function, but they are in an important position in immune function.<\/p>\n\n\n\n<p>For example, because of a weakened immune system, they cannot resist bacteria and viruses and can easily become seriously ill,<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>new strains of coronavirus infection<\/li>\n\n\n\n<li>meningitis<\/li>\n\n\n\n<li>septicemia<\/li>\n\n\n\n<li>pneumonia<\/li>\n\n\n\n<li>bronchitis<\/li>\n<\/ul>\n\n\n\n<p>It is easy to become<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c2-5\"><span class=\"ez-toc-section\" id=\"X-linked_ichthyosis\"><\/span>X-linked ichthyosis<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Ichthyosis is a condition in which the skin all over the body dries up and becomes scaly and flakes off a lot of dandruff.<br>In some cases, abnormalities are seen in organs other than the skin.<\/p>\n\n\n\n<p>A genetic anomaly is the reason why the steroid sulfatase enzyme (STS) is not present in the body.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c2-6\"><span class=\"ez-toc-section\" id=\"Glucose-6-phosphate_dehydrogenase_deficiency\"><\/span>Glucose-6-phosphate dehydrogenase deficiency<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Anemia is more likely to occur.<\/p>\n\n\n\n<p>The reason for this is that reactive oxygen species make red blood cells more susceptible to hemolysis*1.<\/p>\n\n\n\n<p>Glucose-6-phosphate dehydrogenase helps remove reactive oxygen species.<br>In other words, without this enzyme, ROS cannot be removed, and ROS causes hemolysis of red blood cells.<\/p>\n\n\n\n<p>1 Hemolysis: Breakdown of red blood cells.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"600\" height=\"400\" src=\"\/nipt\/wp-content\/uploads\/2021\/12\/621dac062b28a21b172e900646d5070a.png\" alt=\"Diseases prone to companion recessive inheritance\" class=\"wp-image-21381\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\" id=\"c3\"><span class=\"ez-toc-section\" id=\"Companion_recessive_inheritance_is_the_cause_of_the_disease_and_is_inherited\"><\/span>Companion recessive inheritance is the cause of the disease and is inherited<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c3-1\"><span class=\"ez-toc-section\" id=\"Human_gender_is_represented_by_X_and_Y\"><\/span>Human gender is represented by X and Y<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Men are described as X and Y (hereafter XY) and women as X and X (hereafter XX).<\/p>\n\n\n\n<p>Humans have 46 chromosomes.<br>Two of these chromosomes are X and Y or X and X. These are called sex chromosomes.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c3-2\"><span class=\"ez-toc-section\" id=\"Part_of_X_is_abnormal_and_will_be_passed_on\"><\/span>Part of X is abnormal and will be passed on<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Companion recessive inheritance shows an abnormality in part of the X chromosome.<\/p>\n\n\n\n<p>Sex chromosomes (X and Y) record the information that makes up the human body and are like a dictionary<br>It can be likened to a<\/p>\n\n\n\n<p>If, for some reason, a part of the dictionary becomes defective, such as burning or tearing, the human body will lose the defective part.<br>In extreme cases, if the information about the little finger is written on the X chromosome and it is missing, we would be a person without a little finger.<br><br>And the lexicon (X chromosome abnormality) will be passed on to your offspring for generations to come.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c3-3\"><span class=\"ez-toc-section\" id=\"Son_has_onset_of_disease_daughter_rarely_has_onset_of_disease\"><\/span>Son has onset of disease, daughter rarely has onset of disease<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>If you inherit an X chromosome abnormality, your daughter (XX) will not develop the disease.<br>The reason is that women have two X chromosomes.<br>If you have two X chromosomes, if one is abnormal, the other will serve to compensate for the abnormality.<br>If a daughter (XX) develops the disease, both parents must have an abnormal X chromosome, which is very rare.<\/p>\n\n\n\n<p>Son (XY) does not cover anomalies.<br>This is because the Y chromosome has fewer gene types than the X chromosome.<br>To use the analogy from the previous section, if the X chromosome is a dictionary, the Y chromosome is a paperback book.<br>A paperback book cannot replace a dictionary because it does not contain as much information as a dictionary.<\/p>\n\n\n\n<p>The son (XY) who has nothing compensable will develop the disease, and the disease that develops will depend on how many pages of the dictionary are abnormal.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"c3-4\"><span class=\"ez-toc-section\" id=\"Both_daughters_and_sons_inherit\"><\/span>Both daughters and sons inherit<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>Sex chromosomes are inherited either X or Y from the father (XY) or X and X from the mother (XX).<\/p>\n\n\n\n<p>The abnormal X chromosome is inherited with or without onset of disease.<br>However, there is not a 100% chance of inheritance.<\/p>\n\n\n\n<p>How it is inherited depends on whether the father or the mother has the abnormal X chromosome.<\/p>\n\n\n\n<p>Even if a daughter (XX) is born who does not develop the disease, she may still be a carrier*1.<br>If you do not know that your daughter (XX) is a carrier when she gives birth, your grandchildren may be adversely affected.<\/p>\n\n\n\n<p>1 Predisposition: A condition in which a person has an abnormal gene but has not developed the disease.\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"c3-4-1\">If the father has an abnormal X chromosome<\/h4>\n\n\n\n<p>When the father has an abnormal X chromosome, it is not passed on to the son.<br>\u606fThis is because the child inherits the Y chromosome from the father.<\/p>\n\n\n\n<p>However, the daughter always inherits an abnormal X chromosome and is a carrier.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"c3-4-2\">If the mother has an abnormal X chromosome<\/h4>\n\n\n\n<p>If the mother carries the abnormal gene, there is a 50% chance that the gene will be passed on to sons and daughters, and the son will only develop the disease when he inherits it from his mother.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"c4\"><span class=\"ez-toc-section\" id=\"What_you_as_a_parent_can_do_for_your_baby_before_birth_full_chromosome_test\"><\/span>What you, as a parent, can do for your baby before birth [full chromosome test].<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>We recommend a prenatal diagnosis to test the baby&#8217;s gender and genetic makeup.<\/p>\n\n\n\n<p>It is essential to understand about babies because it is essential to raising them.<br>As a parent, don&#8217;t you think it would be difficult to deal with the situation correctly if you don&#8217;t know in advance?<\/p>\n\n\n\n<p>For example, suppose the baby is a boy and is at risk for hemophilia.<br>It&#8217;s horrible to realize the onset of the disease only after the bleeding stops.<\/p>\n\n\n\n<p><a href=\"https:\/\/clinic2.hiro-test.net\/nipt\/nipt\/\">Hiro Clinic NIPT <\/a>\u3067can be sex-determined by prenatal diagnosis.<\/p>\n\n\n\n<p>Companion recessive inheritance, introduced today, can be tested along with gender for the risk of developing the disease with the &#8220;whole chromosome test&#8221;.<\/p>\n\n\n\n<p>I want my baby to be healthy and comfortable after birth.&#8221;<br>To make this wish come true, why don&#8217;t you as a parent know about your baby before birth?<\/p>\n\n\n\n    <a href=\"\/nipt\/nipt\/nipt\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u77e5\u7684\u969c\u304c\u3044\u304c\u308f\u304b\u308bNIPT\u3068\u306f\uff08NIPT\u306e\u57fa\u672c\uff09 <\/div>\n          <div class=\"blog-card-excerpt\">\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u3067\u884c\u3063\u3066\u3044\u308bNIPT\u306e\u307e\u3068\u3081\u3067\u3059\u3002\u30d2\u30ed\u30af\u30ea\u30cb\u30c3\u30af\u306eNIPT\u3067\u306f\u77e5\u7684\u969c\u5bb3\u30fb\u767a\u9054\u969c\u5bb3\u3092\u4f34\u3046\u591a\u6570\u306e\u75be\u60a3\u3092\u51fa\u751f\u524d\u306b\u691c\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067...<\/div>\n      <\/div>\n    <\/a>\n\n\n\n<div class=\"wp-block-group references\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<p id=\"refference\">[References]<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>NATIONAL CANCER INSTITUTE) &#8211; <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/genetics-dictionary\/def\/x-linked-recessive-inheritance\" target=\"_blank\" rel=\"noopener\">X-linked recessive inheritance<\/a><\/li>\n\n\n\n<li>Tohoku University Graduate School of Medicine, Faculty of Medicine, Advanced Developmental Medicine Lecture on Fetal Pediatrics <a href=\"https:\/\/plaza.umin.ac.jp\/~fskel\/cgi-bin\/wiki\/wiki.cgi?page=X%CF%A2%BA%BF%CE%F4%C0%AD%A4%CE%B0%E4%C5%C1%A5%AB%A5%A6%A5%F3%A5%BB%A5%EA%A5%F3%A5%B0\" target=\"_blank\" rel=\"noopener\">Murotsuki Laboratory, Department of Genetic Counseling for Companion Inheritance<\/a>\uff09<\/li>\n\n\n\n<li>Japan Blood Transfusion Products Association &#8211; Japan Blood Transfusion Products Association  <a href=\"http:\/\/www.ketsukyo.or.jp\/plasma\/hemophilia\/hem_01.html\" target=\"_blank\" rel=\"noopener\">Hemophilia and Heredity<\/a><\/li>\n\n\n\n<li>Keio University <a href=\"http:\/\/www.hcc.keio.ac.jp\/ja\/health\/2015\/01\/color-vision-test-before-your-career-choice.html\" target=\"_blank\" rel=\"noopener\">Recommendations for Color Vision Testing &#8211; Before Choosing a Vocation<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/shimizuderm.com\/textbook03\/pdf\/15-02.pdf\" target=\"_blank\" rel=\"noopener\">Atarashii na shinshitsu dermatology, 3rd edition (Hiroshi Shimizu)<\/a><\/li>\n\n\n\n<li>MSD Manuals &#8211; MSD Manuals <a href=\"https:\/\/msdmnls.co\/3wt1LKL\" target=\"_blank\" rel=\"noopener\">Duchenne and Becker muscular dystrophy<\/a><\/li>\n\n\n\n<li>National Hospital Organization Higashi Saitama Hospital <a href=\"https:\/\/bit.ly\/3cFFx06\" target=\"_blank\" rel=\"noopener\">muscular dystrophy<\/a><\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"Summary of this arti&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/xlinked-recessive-inheritance\/?lang=en\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":1,"featured_media":25087,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[97],"tags":[],"class_list":["post-72747","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/72747","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=72747"}],"version-history":[{"count":2,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/72747\/revisions"}],"predecessor-version":[{"id":74053,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/72747\/revisions\/74053"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/25087"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=72747"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=72747"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=72747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}