{"id":82804,"date":"2024-09-24T16:53:55","date_gmt":"2024-09-24T07:53:55","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?p=82804"},"modified":"2025-08-04T17:30:44","modified_gmt":"2025-08-04T08:30:44","slug":"open-neural-tube-defects","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/open-neural-tube-defects\/","title":{"rendered":"\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u691c\u67fb\u65b9\u6cd5\u3068NIPT\u306e\u9650\u754c\u306b\u3064\u3044\u3066"},"content":{"rendered":"\n<div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\"><h2 style=\"margin-top:1rem;\">\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081<\/h2><p>\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\uff08ONTDs: Open Neural Tube Defects\uff09\u306f\u3001\u80ce\u5150\u306e\u8133\u3084\u810a\u9ac4\u306e\u767a\u80b2\u7570\u5e38\u3067\u3042\u308a\u3001\u4ee3\u8868\u7684\u306a\u3082\u306e\u3068\u3057\u3066\u810a\u9ac4\u9ac4\u819c\u7624\u3084\u7121\u8133\u75c7\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5947\u5f62\u306f\u3001\u80ce\u5150\u306e\u795e\u7d4c\u7ba1\u304c\u5b8c\u5168\u306b\u9589\u3058\u306a\u3044\u305f\u3081\u306b\u767a\u751f\u3057\u307e\u3059\u3002\u3053\u306e\u7a2e\u306e\u7570\u5e38\u306f\u3001\u9069\u5207\u306a\u8a3a\u65ad\u3068\u7ba1\u7406\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306b\u8ab0\u306e\u5b50\u304b<br \/>\n\u5206\u304b\u308bDNA\u89aa\u5b50\u9451\u5b9a<\/p>\n<p class=\"btn\">\u8a73\u3057\u304f\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/open-neural-tube-defects\/#NIPT%E6%A4%9C%E6%9F%BB%E3%81%A8%E3%81%AF%EF%BC%9F\" >NIPT\u691c\u67fb\u3068\u306f\uff1f<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/open-neural-tube-defects\/#%E9%96%8B%E6%94%BE%E6%80%A7%E7%A5%9E%E7%B5%8C%E7%AE%A1%E5%A5%87%E5%BD%A2%E3%81%AE%E8%A8%BA%E6%96%AD%E6%96%B9%E6%B3%95\" >\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u8a3a\u65ad\u65b9\u6cd5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/open-neural-tube-defects\/#NIPT%E6%A4%9C%E6%9F%BB%E3%81%AE%E9%99%90%E7%95%8C\" >NIPT\u691c\u67fb\u306e\u9650\u754c<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/open-neural-tube-defects\/#%E3%81%BE%E3%81%A8%E3%82%81\" >\u307e\u3068\u3081<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NIPT%E6%A4%9C%E6%9F%BB%E3%81%A8%E3%81%AF%EF%BC%9F\"><\/span>NIPT\u691c\u67fb\u3068\u306f\uff1f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>\uff08\u975e\u4fb5\u8972\u7684\u51fa\u751f\u524d\u907a\u4f1d\u5b66\u7684\u691c\u67fb\uff09\u306f\u3001\u6bcd\u4f53\u8840\u6db2\u4e2d\u306e\u80ce\u5150\u7531\u6765DNA\u3092\u5206\u6790\u3057\u3001\u80ce\u5150\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chromosomal-abnormality\/\">\u67d3\u8272\u4f53\u7570\u5e38<\/a>\uff08\u4f8b\u3048\u3070\u3001<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/nipt\/testing\/\">\u30c0\u30a6\u30f3\u75c7<\/a>\u5019\u7fa4\u3001\u30a8\u30c9\u30ef\u30fc\u30ba\u75c7\u5019\u7fa4\u3001\u30d1\u30c8\u30a6\u75c7\u5019\u7fa4\u306a\u3069\uff09\u3092\u9ad8\u7cbe\u5ea6\u3067\u691c\u51fa\u3059\u308b\u65b9\u6cd5\u3067\u3059\u3002NIPT\u306f\u3001<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chromosomal-abnormality\/\">\u67d3\u8272\u4f53\u7570\u5e38<\/a>\u306b\u7279\u5316\u3057\u3066\u304a\u308a\u3001\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u691c\u51fa\u306b\u306f\u9069\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n    <a href=\"\/nipt\/nipt-types-comparison-guide\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">NIPT\uff08\u65b0\u578b\u51fa\u751f\u524d\u8a3a\u65ad\uff09\u306e\u7a2e\u985e\u3068\u7cbe\u5ea6\u3092\u3084\u3055\u3057\u304f\u89e3\u8aac\uff1a\u9078\u3073\u65b9\u306e\u53c2\u8003\u306b <\/div>\n          <div class=\"blog-card-excerpt\">NIPT\uff08\u65b0\u578b\u51fa\u751f\u524d\u8a3a\u65ad\uff09\u306e\u57fa\u790e\u304b\u3089\u3001\u691c\u67fb\u6cd5\u306e\u9055\u3044\u3001\u9078\u3073\u65b9\u30012025\u5e74\u6642\u70b9\u306e\u6700\u65b0\u6280\u8853\u3068\u7d71\u8a08\u307e\u3067\u3092\u89e3\u8aac\u3002\u60a3\u8005\u5411\u3051\u3068\u533b\u7642\u8005\u5411\u3051\u306e\u53c2\u8003\u306b\u3002\uff5c\u30d2\u30ed\u30af...<\/div>\n      <\/div>\n    <\/a>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"\/nipt\/wp-content\/uploads\/2024\/09\/30342953_m-1-1024x683.jpg\" alt=\"\u533b\u5e2b\" class=\"wp-image-82809\"\/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E9%96%8B%E6%94%BE%E6%80%A7%E7%A5%9E%E7%B5%8C%E7%AE%A1%E5%A5%87%E5%BD%A2%E3%81%AE%E8%A8%BA%E6%96%AD%E6%96%B9%E6%B3%95\"><\/span>\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u8a3a\u65ad\u65b9\u6cd5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u8a3a\u65ad\u306b\u306f\u3001\u4e3b\u306b\u4ee5\u4e0b\u306e\u65b9\u6cd5\u304c\u7528\u3044\u3089\u308c\u307e\u3059<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>AFP\uff08\u03b1\u30d5\u30a7\u30c8\u30d7\u30ed\u30c6\u30a4\u30f3\uff09\u691c\u67fb<\/strong>\uff1a\n<ul class=\"wp-block-list\">\n<li>AFP\u306f\u3001\u80ce\u5150\u306e\u809d\u81d3\u3067\u751f\u6210\u3055\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u6bcd\u4f53\u8840\u6e05\u3084\u7f8a\u6c34\u4e2d\u306eAFP\u6fc3\u5ea6\u304c\u7570\u5e38\u306b\u9ad8\u3044\u5834\u5408\u3001\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002<\/li>\n\n\n\n<li>AFP\u691c\u67fb\u306f\u3001\u901a\u5e38\u598a\u5a2015\u301c20\u9031\u306e\u9593\u306b\u884c\u308f\u308c\u307e\u3059\u3002\u9ad8\u5024\u306e\u5834\u5408\u306f\u3001\u8ffd\u52a0\u306e\u8a3a\u65ad\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u30a8\u30b3\u30fc\u691c\u67fb\uff08\u8d85\u97f3\u6ce2\u691c\u67fb\uff09<\/strong>\uff1a\n<ul class=\"wp-block-list\">\n<li>\u8d85\u97f3\u6ce2\u691c\u67fb\u306f\u3001\u80ce\u5150\u306e\u8a73\u7d30\u306a\u753b\u50cf\u3092\u63d0\u4f9b\u3057\u3001\u810a\u9ac4\u3084\u8133\u306e\u7570\u5e38\u3092\u8996\u899a\u7684\u306b\u78ba\u8a8d\u3059\u308b\u306e\u306b\u6709\u52b9\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u598a\u5a2018\u301c22\u9031\u306e\u9593\u306b\u884c\u308f\u308c\u308b\u8a73\u7d30\u8d85\u97f3\u6ce2\u691c\u67fb\u3067\u3001\u810a\u9ac4\u9ac4\u819c\u7624\u3084\u7121\u8133\u75c7\u306a\u3069\u306e\u795e\u7d4c\u7ba1\u5947\u5f62\u3092\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>\u30af\u30ef\u30c8\u30ed\u691c\u67fb<\/strong>\uff1a\n<ul class=\"wp-block-list\">\n<li>\u30af\u30ef\u30c8\u30ed\u691c\u67fb\u306f\u3001\u6bcd\u4f53\u8840\u6e05\u4e2d\u306e4\u3064\u306e\u30de\u30fc\u30ab\u30fc\uff08AFP\u3001hCG\u3001\u30a8\u30b9\u30c8\u30ea\u30aa\u30fc\u30eb\u3001\u30a4\u30f3\u30d2\u30d3\u30f3A\uff09\u3092\u6e2c\u5b9a\u3057\u3001\u795e\u7d4c\u7ba1\u5947\u5f62\u3084<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chromosomal-abnormality\/\">\u67d3\u8272\u4f53\u7570\u5e38<\/a>\u306e\u30ea\u30b9\u30af\u3092\u8a55\u4fa1\u3059\u308b\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u30c6\u30b9\u30c8\u3067\u3059\u3002<\/li>\n\n\n\n<li>\u30af\u30ef\u30c8\u30ed\u691c\u67fb\u306e\u7d50\u679c\u306b\u57fa\u3065\u3044\u3066\u3001\u3055\u3089\u306a\u308b\u8a3a\u65ad\u691c\u67fb\u304c\u63a8\u5968\u3055\u308c\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n    <a href=\"\/nipt\/neural-tube-closure-defect\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u795e\u7d4c\u7ba1\u9589\u9396\u969c\u5bb3\u306f\u3044\u3064\u308f\u304b\u308b\uff1f\u8449\u9178\u3068\u306e\u95a2\u4fc2\u3082\u89e3\u8aac\u3010\u533b\u5e2b\u76e3\u4fee\u3011 <\/div>\n          <div class=\"blog-card-excerpt\">\u795e\u7d4c\u7ba1\u9589\u9396\u969c\u5bb3\u306f\u3001\u598a\u5a20\u521d\u671f\u306b\u795e\u7d4c\u7ba1\u306e\u5f62\u6210\u304c\u969c\u5bb3\u3055\u308c\u3066\u8d77\u3053\u308b\u7121\u8133\u75c7\u3084\u4e8c\u5206\u810a\u690e\u306a\u3069\u306e\u75be\u60a3\u306e\u3053\u3068\u3067\u3059\u3002\u8449\u9178\u306e\u6b20\u4e4f\u304c\u4e3b\u306a\u539f\u56e0\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053...<\/div>\n      <\/div>\n    <\/a>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306b\u8ab0\u306e\u5b50\u304b<br \/>\n\u5206\u304b\u308bDNA\u89aa\u5b50\u9451\u5b9a<\/p>\n<p class=\"btn\">\u8a73\u3057\u304f\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"NIPT%E6%A4%9C%E6%9F%BB%E3%81%AE%E9%99%90%E7%95%8C\"><\/span>NIPT\u691c\u67fb\u306e\u9650\u754c<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>NIPT\u691c\u67fb\u306f\u3001\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u691c\u51fa\u306b\u306f\u9069\u3057\u3066\u3044\u307e\u305b\u3093\u3002NIPT\u306f\u3001\u80ce\u5150\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chromosomal-abnormality\/\">\u67d3\u8272\u4f53\u7570\u5e38<\/a>\u3092\u691c\u51fa\u3059\u308b\u305f\u3081\u306b\u8a2d\u8a08\u3055\u308c\u3066\u304a\u308a\u3001\u795e\u7d4c\u7ba1\u306e\u767a\u80b2\u7570\u5e38\u306b\u306f\u5bfe\u5fdc\u3057\u3066\u3044\u306a\u3044\u305f\u3081\u3067\u3059\u3002NIPT\u306e\u7d50\u679c\u304c\u6b63\u5e38\u3067\u3082\u3001\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u5b58\u5728\u3092\u5426\u5b9a\u3059\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p>\u958b\u653e\u6027\u795e\u7d4c\u7ba1\u5947\u5f62\u306f\u3001NIPT\u691c\u67fb\u3067\u306f\u691c\u51fa\u3067\u304d\u307e\u305b\u3093\u3002\u6700\u9069\u306a\u691c\u67fb\u65b9\u6cd5\u306f\u3001AFP\u691c\u67fb\u3068\u30a8\u30b3\u30fc\u691c\u67fb\u3067\u3059\u3002AFP\u691c\u67fb\u3067\u306f\u3001\u6bcd\u4f53\u8840\u6e05\u4e2d\u306eAFP\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u3001\u9ad8\u5024\u304c\u793a\u3055\u308c\u308b\u5834\u5408\u306b\u306f\u795e\u7d4c\u7ba1\u5947\u5f62\u306e\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3059\u3002\u8a73\u7d30\u306a\u30a8\u30b3\u30fc\u691c\u67fb\u3067\u306f\u3001\u80ce\u5150\u306e\u810a\u9ac4\u3084\u8133\u306e\u753b\u50cf\u3092\u78ba\u8a8d\u3057\u3001\u5177\u4f53\u7684\u306a\u7570\u5e38\u3092\u8a3a\u65ad\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30af\u30ef\u30c8\u30ed\u691c\u67fb\u3082\u6709\u52b9\u306a\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u624b\u6bb5\u3067\u3042\u308a\u3001AFP\u691c\u67fb\u3092\u542b\u30804\u3064\u306e\u30de\u30fc\u30ab\u30fc\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u3067\u3001\u795e\u7d4c\u7ba1\u5947\u5f62\u3084<a 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