{"id":83505,"date":"2024-11-14T14:19:08","date_gmt":"2024-11-14T05:19:08","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?p=83505"},"modified":"2025-08-12T10:16:48","modified_gmt":"2025-08-12T01:16:48","slug":"chordoma","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/","title":{"rendered":"\u30b3\u30eb\u30c9\u30fc\u30de\u3063\u3066\u306a\u306b\uff1fNIPT\u3067\u691c\u67fb\u3067\u304d\u308b\uff1f\u3010\u533b\u5e2b\u76e3\u4fee\u3011"},"content":{"rendered":"\n<div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\"><h2 style=\"margin-top:1rem;\">\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081<\/h2><p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u810a\u7d22\u3068\u3044\u3046\u810a\u690e\u306e\u5f62\u6210\u306b\u95a2\u308f\u308b\u80da\u306e\u69cb\u9020\u304b\u3089\u767a\u751f\u3059\u308b\u307e\u308c\u306a\u60aa\u6027\u816b\u760d\u3067\u3059\u3002\u4e3b\u306b\u6210\u4eba\u306b\u767a\u75c7\u3057\u3001\u6210\u9577\u304c\u9045\u3044\u305f\u3081\u65e9\u671f\u306b\u8a3a\u65ad\u3059\u308b\u306e\u304c\u96e3\u3057\u304f\u3001\u9032\u884c\u5f8c\u306b\u767a\u898b\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u75c7\u72b6\u3084\u8a3a\u65ad\u65b9\u6cd5\u3001\u6cbb\u7642\u6cd5\u3001\u4e88\u5f8c\u306a\u3069\u306b\u3064\u3044\u3066\u5206\u304b\u308a\u3084\u3059\u304f\u8aac\u660e\u3057\u307e\u3059\u3002<\/p><\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_84 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E7%97%85%E6%B0%97%E3%81%AE%E5%88%A5%E7%A7%B0\" >\u75c5\u6c17\u306e\u5225\u79f0<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E7%96%BE%E6%82%A3%E6%A6%82%E8%A6%81\" >\u75be\u60a3\u6982\u8981<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E7%97%85%E5%9B%A0%E3%81%A8%E8%A8%BA%E6%96%AD%E3%81%AE%E6%96%B9%E6%B3%95\" >\u75c5\u56e0\u3068\u8a3a\u65ad\u306e\u65b9\u6cd5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E7%96%BE%E6%82%A3%E3%81%AE%E7%97%87%E7%8A%B6%E3%81%A8%E7%AE%A1%E7%90%86%E6%96%B9%E6%B3%95\" >\u75be\u60a3\u306e\u75c7\u72b6\u3068\u7ba1\u7406\u65b9\u6cd5<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E5%B0%86%E6%9D%A5%E3%81%AE%E8%A6%8B%E9%80%9A%E3%81%97\" >\u5c06\u6765\u306e\u898b\u901a\u3057<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E3%82%82%E3%81%A3%E3%81%A8%E7%9F%A5%E3%82%8A%E3%81%9F%E3%81%84%E6%96%B9%E3%81%B8\" >\u3082\u3063\u3068\u77e5\u308a\u305f\u3044\u65b9\u3078<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/#%E5%BC%95%E7%94%A8%E6%96%87%E7%8C%AE\" >\u5f15\u7528\u6587\u732e<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%97%85%E6%B0%97%E3%81%AE%E5%88%A5%E7%A7%B0\"><\/span>\u75c5\u6c17\u306e\u5225\u79f0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Chdm<\/li>\n\n\n\n<li>Notochordoma<\/li>\n\n\n\n<li>Notochordal sarcoma<\/li>\n\n\n\n<li>Chordoepithelioma<\/li>\n\n\n\n<li>Chordocarcinoma<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%96%BE%E6%82%A3%E6%A6%82%E8%A6%81\"><\/span>\u75be\u60a3\u6982\u8981<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"1024\" height=\"20\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/6f91510bd4547f6993a429d3e94f9dca-1024x20.png\" alt=\"6q27\" class=\"wp-image-90111\"\/><\/figure><\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u810a\u690e\u306e\u5f62\u6210\u306b\u95a2\u308f\u308b\u80da\u306e\u69cb\u9020\u3067\u3042\u308b\u810a\u7d22\uff08\u305b\u304d\u3055\u304f\uff09\u306e\u6b8b\u308a\u304b\u3089\u767a\u751f\u3059\u308b\u307e\u308c\u306a\u60aa\u6027\u816b\u760d\u3067\u3059\u3002\u4e3b\u306b\u6210\u4eba\u306b\u767a\u75c7\u3057\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\u306e\u816b\u760d\u3067\u306f\u7d040.2%\u3001\u539f\u767a\u6027\u9aa8\u816b\u760d\u3067\u306f2\u301c4%\u3092\u5360\u3081\u3066\u3044\u307e\u3059\u3002\u767a\u75c7\u7387\u306f\u7d04200\u4e07\u4eba\u306b1\u4eba\u3068\u3055\u308c\u3001\u7537\u5973\u6bd4\u306f2:1\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u75c7\u72b6\u306f\u816b\u760d\u306e\u4f4d\u7f6e\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u6700\u3082\u4e00\u822c\u7684\u306a\u767a\u751f\u90e8\u4f4d\u306f\u3001\u810a\u690e\u306e\u57fa\u90e8\u306b\u3042\u308b\u4ed9\u9aa8\uff08\u305b\u3093\u3053\u3064\uff09\u3001\u982d\u84cb\u5e95\u306e\u30af\u30e9\u30a4\u30d0\u30b9\u3001\u305d\u3057\u3066\u810a\u67f1\u306b\u6cbf\u3063\u305f\u90e8\u5206\u3067\u3059\u3002\u8133\u5185\u306b\u816b\u760d\u304c\u3042\u308b\u5834\u5408\u3001\u4e3b\u306a\u75c7\u72b6\u3068\u3057\u3066\u3001\u3082\u306e\u304c\u4e8c\u91cd\u306b\u898b\u3048\u308b\u8907\u8996\uff08\u3075\u304f\u3057\uff09\u3001\u98f2\u307f\u8fbc\u307f\u306b\u304f\u3055\u3001\u982d\u75db\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u9854\u9762\u795e\u7d4c\u9ebb\u75fa\u306a\u3069\u306e\u795e\u7d4c\u75c7\u72b6\u3082\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u810a\u690e\u306b\u816b\u760d\u304c\u3067\u304d\u308b\u3068\u3001\u9996\u3084\u80cc\u4e2d\u3001\u5c3e\u9aa8\u4ed8\u8fd1\u306b\u75db\u307f\u304c\u73fe\u308c\u308b\u307b\u304b\u3001\u8155\u3084\u811a\u306b\u75db\u307f\u3084\u3057\u3073\u308c\u3001\u7b4b\u529b\u306e\u4f4e\u4e0b\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u8180\u80f1\u3084\u8178\u306e\u30c8\u30e9\u30d6\u30eb\u3082\u767a\u751f\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u6210\u9577\u304c\u9045\u304f\u3001\u5468\u56f2\u306e\u9aa8\u3092\u7834\u58ca\u3057\u306a\u304c\u3089\u3001\u96a3\u63a5\u3059\u308b\u8edf\u90e8\u7d44\u7e54\u306b\u5e83\u304c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30ea\u30f3\u30d1\u7bc0\u3084\u80ba\u3001\u809d\u81d3\u3001\u9aa8\u306b\u8ee2\u79fb\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u9060\u9694\u8ee2\u79fb\u306f\u6bd4\u8f03\u7684\u5c11\u306a\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u6210\u4eba\u306b\u591a\u304f\u898b\u3089\u308c\u3001\u5b50\u4f9b\u3084\u601d\u6625\u671f\u306e\u60a3\u8005\u306f5%\u672a\u6e80\u3067\u3059\u3002\u6700\u3082\u4e00\u822c\u7684\u306b\u767a\u751f\u3059\u308b\u90e8\u4f4d\u306f\u3001\u8776\u5f62\u9aa8\uff08\u3061\u3087\u3046\u3051\u3044\u3053\u3064\uff09\u3068\u5f8c\u982d\u9aa8\u306e\u9593\u3001\u810a\u690e\u3001\u4ed9\u5c3e\u90e8\u3067\u3059\u3002\u816b\u760d\u306f\u6210\u9577\u304c\u9045\u3044\u3082\u306e\u306e\u3001\u5c40\u6240\u7684\u306b\u653b\u6483\u7684\u306b\u6210\u9577\u3057\u3001\u5468\u56f2\u306e\u7d44\u7e54\u306b\u91cd\u5927\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n    <a href=\"\/nipt\/japanese-mothers-aged-35-and-older\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">35\u6b73\u4ee5\u4e0a\u306e\u65e5\u672c\u4eba\u6bcd\u89aa\u306b\u5bfe\u3059\u308b\u598a\u5a20\u7b2c2\u671f\u7f8a\u6c34\u7a7f\u523a\u6642\u306e\u67d3\u8272\u4f53\u7570\u5e38\u306e\u5e74\u9f62\u7279\u7570\u7684\u767a\u751f\u7387:5484\u4f8b\u306e\u5171\u540c\u7814\u7a76 <\/div>\n          <div class=\"blog-card-excerpt\">...<\/div>\n      <\/div>\n    <\/a>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%97%85%E5%9B%A0%E3%81%A8%E8%A8%BA%E6%96%AD%E3%81%AE%E6%96%B9%E6%B3%95\"><\/span>\u75c5\u56e0\u3068\u8a3a\u65ad\u306e\u65b9\u6cd5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u810a\u690e\u3092\u5f62\u6210\u3059\u308b\u521d\u671f\u306e\u80da\u306e\u69cb\u9020\u3067\u3042\u308b\u810a\u7d22\uff08\u305b\u304d\u3055\u304f\uff09\u306e\u6b8b\u308a\u304b\u3089\u767a\u751f\u3059\u308b\u307e\u308c\u306a\u60aa\u6027\u816b\u760d\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u816b\u760d\u306f\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3084\u7d30\u80de\u5185\u306e\u7d4c\u8def\u304c\u6b63\u5e38\u306b\u50cd\u304b\u306a\u304f\u306a\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001CRISPR-Cas9\u6280\u8853\u3092\u4f7f\u7528\u3057\u305f\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u55aa\u5931\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u3088\u308a\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u7d30\u80de\u306e\u6210\u9577\u3068\u751f\u5b58\u306b\u91cd\u8981\u306a\u3055\u307e\u3056\u307e\u306a\u907a\u4f1d\u5b50\u304c\u7279\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u8907\u96d1\u306a\u5206\u5b50\u69cb\u9020\u306b\u95a2\u308f\u308b\u591a\u304f\u306e\u6a5f\u80fd\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306b\u95a2\u9023\u3059\u308b\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u306b\u306f\u3001PTPN11\u3001ADAR\u3001PRKRA\u3001LUC7L2\u3001SRRM2\u3001SLC2A1\u3001SLC7A5\u3001FANCM\u3001AHR\u3001ARNT\u3001HEATR3\u3001UBIAD1\u3001IER3IP1\u3001PRKAR1A\u3001ZEB2\u3001DSCC1\u3001OTUD5\u306a\u3069\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u3001\u7d30\u80de\u306e\u5206\u5316\u3084\u5897\u6b96\u3001\u4ee3\u8b1d\u3001\u514d\u75ab\u8abf\u7bc0\u3001RNA\u306e\u30b9\u30d7\u30e9\u30a4\u30b7\u30f3\u30b0\uff08\u907a\u4f1d\u5b50\u306e\u8ee2\u5199\u5f8c\u306e\u51e6\u7406\uff09\u3001\u7d30\u80de\u5185\u8f38\u9001\u3001DNA\u8907\u88fd\u3084\u4fee\u5fa9\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u751f\u547d\u6d3b\u52d5\u306b\u95a2\u308f\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306e\u3044\u304f\u3064\u304b\u306f\u3001\u4ee5\u524d\u306e\u7814\u7a76\u3067\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u751f\u7269\u5b66\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304a\u308a\u3001\u305d\u306e\u91cd\u8981\u6027\u304c\u518d\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/31510744_s.jpg\" alt=\"\u7d46\u5275\u818f\" class=\"wp-image-88803\"\/><\/figure><\/div>\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u7279\u306b\u3001\u767a\u9054\u904e\u7a0b\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\uff08TBXT\u3001SOX9\u3001ZEB2\uff09\u3001\u7d30\u80de\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u62c5\u3046\u907a\u4f1d\u5b50\uff08PTPN11\u3001EGFR\uff09\u3001\u4ee3\u8b1d\u3092\u8abf\u6574\u3059\u308b\u907a\u4f1d\u5b50\uff08AHR\u3001ARNT\u3001SLC2A1\u3001SLC7A5\uff09\u306a\u3069\u304c\u6319\u3052\u3089\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u7d30\u80de\u5468\u671f\u3084DNA\u4fee\u5fa9\u3092\u5236\u5fa1\u3059\u308b\u907a\u4f1d\u5b50\uff08CDK6\u3001FANCM\uff09\u3001\u514d\u75ab\u8abf\u7bc0\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\uff08ADAR\u3001PRKRA\uff09\u3001RNA\u51e6\u7406\u306b\u95a2\u308f\u308b\u907a\u4f1d\u5b50\uff08LUC7L2\u3001SRRM2\uff09\u3082\u91cd\u8981\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\u306f\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u7d30\u80de\u306e\u751f\u5b58\u3068\u6210\u9577\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u305f\u3081\u306b\u5354\u529b\u3057\u3066\u50cd\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3055\u3089\u306b\u3001\u7814\u7a76\u3067\u306f\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u7d30\u80de\u3088\u308a\u3082\u975e\u30b3\u30eb\u30c9\u30fc\u30de\u7d30\u80de\u3067\u4f9d\u5b58\u5ea6\u304c\u9ad8\u3044\u907a\u4f1d\u5b50\u3082\u7279\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u907a\u4f1d\u5b50\uff08MED1\u3001MRPS10\u3001DDX39B\uff09\u306f\u3001\u975e\u30b3\u30eb\u30c9\u30fc\u30de\u7d30\u80de\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u7d4c\u8def\u304c\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u304a\u308a\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u3068\u4ed6\u306e\u7d30\u80de\u30bf\u30a4\u30d7\u3068\u306e\u9055\u3044\u3092\u7406\u89e3\u3059\u308b\u305f\u3081\u306e\u65b0\u3057\u3044\u8996\u70b9\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u308c\u307e\u3067\u306e\u7814\u7a76\u306b\u3088\u308a\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u7d30\u80de\u5185\u3067\u91cd\u8981\u306a\u30d7\u30ed\u30bb\u30b9\u3092\u5236\u5fa1\u3059\u308b\u8907\u96d1\u306a\u907a\u4f1d\u5b50\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u5206\u5b50\u75c5\u7406\u306b\u3064\u3044\u3066\u8cb4\u91cd\u306a\u6d1e\u5bdf\u304c\u5f97\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u75c5\u6c17\u306e\u539f\u56e0\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3059\u53ef\u80fd\u6027\u306e\u3042\u308b\u8ee2\u5199\u56e0\u5b50\u306a\u3069\u3001\u307e\u3060\u89e3\u660e\u3055\u308c\u3066\u3044\u306a\u3044\u8981\u7d20\u3082\u591a\u304f\u3001\u4eca\u5f8c\u306e\u7814\u7a76\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"950\" height=\"500\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/b727d8783df54a3afc39e886ac1a59bf.png\" alt=\"chromo6\" class=\"wp-image-90119\"\/><\/figure><\/div>\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u907a\u4f1d\u7684\u306a\u8981\u56e0\u306b\u52a0\u3048\u3066\u3001\u74b0\u5883\u8981\u56e0\u3082\u95a2\u4fc2\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001\u52a0\u9f62\u3001\u55ab\u7159\u3001\u80a5\u6e80\u3001\u30b9\u30c8\u30ec\u30b9\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u6442\u53d6\u306a\u3069\u3001\u4e00\u822c\u7684\u306a\u304c\u3093\u30ea\u30b9\u30af\u56e0\u5b50\u304c\u542b\u307e\u308c\u307e\u3059\u3002\u65e9\u671f\u304b\u3064\u6b63\u78ba\u306a\u8a3a\u65ad\u304c\u91cd\u8981\u3067\u3042\u308a\u3001\u3053\u308c\u306b\u3088\u308a\u52b9\u679c\u7684\u306a\u6cbb\u7642\u3068\u4e88\u5f8c\u306e\u6539\u5584\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u73fe\u5728\u30b3\u30eb\u30c9\u30fc\u30de\u60a3\u8005\u306e5\u5e74\u751f\u5b58\u7387\u306f\u4f4e\u304f\u3001\u65b0\u305f\u306a\u65e9\u671f\u8a3a\u65ad\u65b9\u6cd5\u304c\u5fc5\u8981\u3067\u3059\u3002\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u75c7\u72b6\u306e\u9032\u884c\u304c\u9045\u3044\u305f\u3081\u3001\u75c5\u6c17\u304c\u9032\u884c\u3059\u308b\u307e\u3067\u60a3\u8005\u304c\u533b\u5e2b\u306b\u76f8\u8ac7\u3057\u306a\u3044\u3053\u3068\u304c\u591a\u304f\u3001\u65e9\u671f\u306b\u8a3a\u65ad\u3059\u308b\u306e\u304c\u96e3\u3057\u3044\u3068\u3044\u3046\u8ab2\u984c\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u810a\u690e\u306e\u521d\u671f\u306e\u69cb\u9020\u3067\u3042\u308b\u810a\u7d22\uff08\u305b\u304d\u3055\u304f\uff09\u306e\u6b8b\u308a\u304b\u3089\u767a\u751f\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u3084\u826f\u6027\u810a\u7d22\u816b\u760d\u3001\u810a\u7d22\u81ea\u4f53\u306b\u898b\u3089\u308c\u308b\u300c\u30d6\u30e9\u30ad\u30e5\u30ea\u30fc\u300d\u3068\u3044\u3046\u8ee2\u5199\u56e0\u5b50\u304c\u904e\u5270\u306b\u767a\u73fe\u3057\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u652f\u6301\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u305f\u3081\u3001\u30d6\u30e9\u30ad\u30e5\u30ea\u30fc\u3092\u4f7f\u3063\u305f\u514d\u75ab\u67d3\u8272\u304c\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u8a3a\u65ad\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u65b9\u6cd5\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u810a\u690e\u306e\u3069\u3053\u306b\u3067\u3082\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u75c7\u72b6\u306f\u816b\u760d\u306e\u4f4d\u7f6e\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u4ed9\u9aa8\u306b\u767a\u751f\u3057\u305f\u5834\u5408\u3001\u80cc\u4e2d\u306e\u75db\u307f\u3001\u5c3f\u3084\u4fbf\u306e\u969c\u5bb3\u3001\u795e\u7d4c\u969c\u5bb3\u3001\u6b69\u884c\u306e\u554f\u984c\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3001\u30af\u30e9\u30a4\u30d0\u30b9\uff08\u982d\u84cb\u5e95\uff09\u306b\u767a\u751f\u3057\u305f\u5834\u5408\u3001\u982d\u75db\u3001\u8907\u8996\uff08\u4e8c\u91cd\u8996\uff09\u3001\u8133\u795e\u7d4c\u306b\u95a2\u3059\u308b\u554f\u984c\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u816b\u760d\u306f\u6210\u9577\u304c\u9045\u304f\u3001\u75c7\u72b6\u3082\u7279\u5b9a\u3057\u306b\u304f\u3044\u305f\u3081\u3001\u8a3a\u65ad\u304c\u9045\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u306e\u304c\u73fe\u5b9f\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"426\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/31295073_s.jpg\" alt=\"\u304a\u3066\u3066\" class=\"wp-image-87378\"\/><\/figure><\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u5e38\u67d3\u8272\u4f53\u512a\u6027\u907a\u4f1d\u306e\u30d1\u30bf\u30fc\u30f3\u3067\u907a\u4f1d\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u907a\u4f1d\u5b50\u304c\u756a\u53f7\u306e\u3064\u3044\u305f\u67d3\u8272\u4f53\u4e0a\u306b\u3042\u308a\u3001\u89aa\u304b\u30891\u3064\u306e\u5909\u7570\u907a\u4f1d\u5b50\u3092\u53d7\u3051\u7d99\u3052\u3070\u75c5\u6c17\u304c\u767a\u75c7\u3059\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u5e38\u67d3\u8272\u4f53\u512a\u6027\u907a\u4f1d\u75be\u60a3\u3092\u6301\u3064\u4eba\u306f\u3001\u305d\u306e\u5909\u7570\u907a\u4f1d\u5b50\u309250%\u306e\u78ba\u7387\u3067\u5b50\u3069\u3082\u306b\u907a\u4f1d\u3055\u305b\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3082\u3057\u907a\u4f1d\u7684\u306a\u30ea\u30b9\u30af\u304c\u5bb6\u65cf\u306b\u3042\u308b\u5834\u5408\u3001\u30ad\u30e3\u30ea\u30a2\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\uff08\u907a\u4f1d\u5b50\u4fdd\u56e0\u8005\u306e\u691c\u67fb\uff09\u304c\u5f79\u7acb\u3061\u307e\u3059\u3002\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u56e0\u5b50\u304c\u7279\u5b9a\u3055\u308c\u305f\u5834\u5408\u306f\u3001\u5bb6\u65cf\u5168\u4f53\u3067\u4ed6\u306b\u30ea\u30b9\u30af\u304c\u3042\u308b\u304b\u3092\u8abf\u3079\u308b\u305f\u3081\u306b\u30ab\u30b9\u30b1\u30fc\u30c9\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3092\u884c\u3046\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u307e\u305f\u3001\u598a\u5a20\u4e2d\u306e\u65b9\u306b\u306f\u3001\u7279\u306b\u907a\u4f1d\u7684\u30ea\u30b9\u30af\u304c\u3042\u308b\u5834\u5408\u3001\u975e\u4fb5\u8972\u7684<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">\u51fa\u751f\u524d\u8a3a\u65ad<\/a>\uff08<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>\uff09\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002NIPT\u306f\u3001\u7f8a\u6c34\u7a7f\u523a\u3084FISH\uff08\u86cd\u5149 in situ \u30cf\u30a4\u30d6\u30ea\u30c0\u30a4\u30bc\u30fc\u30b7\u30e7\u30f3\uff09\u306a\u3069\u306e\u4fb5\u8972\u7684\u306a\u691c\u67fb\u65b9\u6cd5\u306e\u4ee3\u308f\u308a\u306b\u3001\u5b89\u5168\u3067\u4fe1\u983c\u6027\u306e\u9ad8\u3044\u65b9\u6cd5\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002NIPT\u306f\u6bcd\u89aa\u306e\u8840\u6db2\u304b\u3089\u80ce\u5150\u306e\u7d30\u80de\u3092\u5206\u6790\u3057\u3001\u80ce\u5150\u306e\u30b2\u30ce\u30e0\u3092\u89e3\u6790\u3059\u308b\u3053\u3068\u3067\u3001\u6bcd\u4f53\u3084\u80ce\u5150\u306b\u30ea\u30b9\u30af\u3092\u4f34\u308f\u305a\u306b\u6b63\u78ba\u306a\u7d50\u679c\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001NIPT\u306f\u598a\u5a20\u4e2d\u306e\u5b89\u5168\u306a\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u65b9\u6cd5\u3092\u5e0c\u671b\u3059\u308b\u89aa\u305f\u3061\u306b\u3001\u307e\u3059\u307e\u3059\u4eba\u6c17\u306e\u3042\u308b\u9078\u629e\u80a2\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%96%BE%E6%82%A3%E3%81%AE%E7%97%87%E7%8A%B6%E3%81%A8%E7%AE%A1%E7%90%86%E6%96%B9%E6%B3%95\"><\/span>\u75be\u60a3\u306e\u75c7\u72b6\u3068\u7ba1\u7406\u65b9\u6cd5<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u810a\u690e\u306e\u521d\u671f\u5f62\u6210\u306b\u95a2\u4e0e\u3059\u308b\u810a\u7d22\uff08\u305b\u304d\u3055\u304f\uff09\u306e\u6b8b\u308a\u304b\u3089\u767a\u751f\u3059\u308b\u307e\u308c\u306a\u60aa\u6027\u816b\u760d\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u816b\u760d\u306f\u4e3b\u306b\u982d\u84cb\u5e95\u3001\u53ef\u52d5\u810a\u690e\u3001\u4ed9\u9aa8\u306b\u898b\u3089\u308c\u3001\u6210\u9577\u304c\u9045\u3044\u3082\u306e\u306e\u3001\u60aa\u6027\u306e\u6027\u8cea\u3092\u6301\u3061\u3001\u4e88\u5f8c\u306f\u4e0d\u826f\u3067\u3059\u3002\u816b\u760d\u306f\u75c5\u6c17\u304c\u9032\u884c\u3057\u3066\u304b\u3089\u73fe\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u91cd\u8981\u306a\u795e\u7d4c\u8840\u7ba1\u69cb\u9020\u3092\u56f2\u3080\u3053\u3068\u304c\u3042\u308a\u3001\u5c40\u6240\u7684\u306b\u518d\u767a\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u653e\u5c04\u7dda\u6cbb\u7642\u3084\u5316\u5b66\u7642\u6cd5\u306a\u3069\u3001\u5f93\u6765\u306e\u6cbb\u7642\u6cd5\u306b\u306f\u62b5\u6297\u3092\u793a\u3059\u3053\u3068\u304c\u591a\u304f\u3001\u6cbb\u7642\u304c\u96e3\u3057\u3044\u816b\u760d\u3067\u3059\u3002\u4e88\u5f8c\u306b\u6700\u3082\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u306e\u306f\u3001\u624b\u8853\u3067\u306e\u5207\u9664\u7bc4\u56f2\u3068\u5207\u9664\u5f8c\u306e\u30de\u30fc\u30b8\u30f3\u306e\u78ba\u4fdd\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u6cbb\u7642\u306b\u306f\u3001\u7d4c\u9a13\u8c4a\u5bcc\u306a\u591a\u8077\u7a2e\u30c1\u30fc\u30e0\u306b\u3088\u308b\u9ad8\u5ea6\u306a\u5c02\u9580\u7684\u6cbb\u7642\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5f93\u6765\u306e\u6cbb\u7642\u6cd5\u304c\u52b9\u304d\u306b\u304f\u3044\u3068\u3055\u308c\u3066\u304d\u305f\u30b3\u30eb\u30c9\u30fc\u30de\u3067\u3059\u304c\u3001\u653e\u5c04\u7dda\u6cbb\u7642\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u816b\u760d\u306b\u9ad8\u3044\u653e\u5c04\u7dda\u91cf\u3092\u7167\u5c04\u3057\u3001\u5468\u56f2\u306e\u7d44\u7e54\u3078\u306e\u5f71\u97ff\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u3053\u3068\u304c\u53ef\u80fd\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u907a\u4f1d\u7684\u30fb\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u95a2\u3059\u308b\u7814\u7a76\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u5316\u3055\u308c\u305f\u5316\u5b66\u7642\u6cd5\u304c\u958b\u767a\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u3067\u3082\u3001\u6700\u826f\u306e\u7d50\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u3001\u7d4c\u9a13\u8c4a\u5bcc\u306a\u533b\u5e2b\u30c1\u30fc\u30e0\u306b\u3088\u308b\u6cbb\u7642\u304c\u6700\u3082\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"480\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/31083235_s.jpg\" alt=\"\u8db3\" class=\"wp-image-87423\"\/><\/figure><\/div>\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u75c7\u72b6\u306f\u816b\u760d\u306e\u4f4d\u7f6e\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u982d\u84cb\u5e95\u306b\u767a\u751f\u3057\u305f\u5834\u5408\u3001\u4e00\u822c\u7684\u306a\u75c7\u72b6\u306f\u982d\u75db\u3001\u8133\u795e\u7d4c\u306e\u969c\u5bb3\u3001\u5185\u5206\u6ccc\u7570\u5e38\uff08\u30db\u30eb\u30e2\u30f3\u306e\u554f\u984c\uff09\u3067\u3059\u3002\u53ef\u52d5\u810a\u690e\u3084\u4ed9\u9aa8\u306b\u767a\u751f\u3057\u305f\u5834\u5408\u306f\u3001\u5c40\u6240\u7684\u306a\u75db\u307f\u3084\u795e\u7d4c\u969c\u5bb3\uff08\u30e9\u30b8\u30af\u30eb\u30d1\u30b7\u30fc\uff09\u3001\u810a\u9ac4\u969c\u5bb3\uff08\u30df\u30a8\u30ed\u30d1\u30b7\u30fc\uff09\u3001\u6392\u5c3f\u3084\u6392\u4fbf\u306e\u554f\u984c\u304c\u73fe\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u6210\u9577\u304c\u9045\u3044\u305f\u3081\u3001\u767a\u898b\u3055\u308c\u305f\u6642\u306b\u306f\u3059\u3067\u306b\u5927\u304d\u304f\u306a\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u89e6\u8a3a\u3067\u816b\u760d\u304c\u78ba\u8a8d\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u9838\u690e\u306b\u767a\u751f\u3057\u305f\u5834\u5408\u306f\u3001\u5468\u56f2\u306e\u8edf\u90e8\u7d44\u7e54\u306b\u4fb5\u5165\u3057\u3001\u98f2\u307f\u8fbc\u307f\u306e\u56f0\u96e3\uff08\u56a5\u4e0b\u969c\u5bb3\uff09\u3084\u6c17\u9053\u306e\u9589\u585e\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4ed9\u9aa8\u306b\u767a\u751f\u3057\u305f\u5834\u5408\u306f\u3001\u4ed9\u9aa8\u524d\u90e8\u3084\u9aa8\u76e4\u306b\u307e\u3067\u5e83\u304c\u308a\u3001\u4fbf\u79d8\u3084\u5c3f\u9589\u3001\u5185\u81d3\u306e\u75db\u307f\u306a\u3069\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u4e3b\u306b\u786c\u819c\u5916\u7a7a\u9593\u304b\u3089\u767a\u751f\u3057\u307e\u3059\u304c\u3001\u7a00\u306b\u786c\u819c\u5185\u306b\u9032\u5c55\u3057\u3001\u810a\u9ac4\u5185\u306b\u5e83\u304c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u4f53\u306e\u4e2d\u592e\u306b\u4f4d\u7f6e\u3057\u3001\u91cd\u8981\u306a\u795e\u7d4c\u8840\u7ba1\u69cb\u9020\u3092\u5dfb\u304d\u8fbc\u3080\u50be\u5411\u304c\u3042\u308a\u3001\u6210\u9577\u304c\u9045\u304f\u3001\u5f93\u6765\u306e\u6cbb\u7642\u6cd5\u306b\u306f\u62b5\u6297\u3092\u793a\u3059\u305f\u3081\u3001\u6cbb\u7642\u304c\u975e\u5e38\u306b\u96e3\u3057\u3044\u816b\u760d\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u624b\u8853\u6280\u8853\u306e\u9032\u6b69\u3001\u753b\u50cf\u8a98\u5c0e\u6280\u8853\u3001\u653e\u5c04\u7dda\u6cbb\u7642\u6226\u7565\u3001\u305d\u3057\u3066\u30bf\u30fc\u30b2\u30c3\u30c8\u5206\u5b50\u6cbb\u7642\u306e\u767b\u5834\u306b\u3088\u308a\u3001\u60a3\u8005\u306e\u4e88\u5f8c\u304c\u6539\u5584\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u6700\u826f\u306e\u6cbb\u7642\u7d50\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u3001\u5c02\u9580\u7684\u306a\u6cbb\u7642\u304c\u53ef\u80fd\u306a\u9ad8\u5ea6\u306a\u533b\u7642\u6a5f\u95a2\u3067\u3001\u5305\u62ec\u7684\u306a\u6cbb\u7642\u304c\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"360\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/2781799_s.jpg\" alt=\"\u8133\" class=\"wp-image-88607\"\/><\/figure><\/div>\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u6700\u9069\u306a\u6cbb\u7642\u6cd5\u306f\u3001\u816b\u760d\u306e\u5b8c\u5168\u5207\u9664\u3067\u3059\u304c\u3001\u305d\u306e\u4f4d\u7f6e\u306b\u3088\u308a\u5b8c\u5168\u306b\u5207\u9664\u3059\u308b\u306e\u304c\u96e3\u3057\u304f\u3001\u518d\u767a\u7387\u304c\u9ad8\u3044\u3067\u3059\u3002\u5207\u9664\u304c\u4e0d\u53ef\u80fd\u306a\u5834\u5408\u306f\u653e\u5c04\u7dda\u6cbb\u7642\u304c\u884c\u308f\u308c\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u88dc\u52a9\u7684\u306a\u653e\u5c04\u7dda\u6cbb\u7642\u304c\u8ffd\u52a0\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u5207\u9664\u4e0d\u53ef\u80fd\u306a\u30b3\u30eb\u30c9\u30fc\u30de\u306b\u5bfe\u3059\u308b\u9ad8\u7dda\u91cf\u306e\u5149\u5b50\u307e\u305f\u306f\u967d\u5b50\u653e\u5c04\u7dda\u6cbb\u7642\u306f\u30015\u5e74\u5f8c\u306e\u5c40\u6240\u5236\u5fa1\u7387\u304c\u7d0485%\u3001\u75c5\u6c17\u7279\u7570\u7684\u751f\u5b58\u7387\u304c\u7d0489%\u3001\u9060\u9694\u8ee2\u79fb\u306e\u767a\u751f\u7387\u304c\u7d0420%\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u5f93\u6765\u306e\u5316\u5b66\u7642\u6cd5\u306b\u306f\u62b5\u6297\u304c\u5f37\u3044\u3067\u3059\u304c\u3001\u30bf\u30fc\u30b2\u30c3\u30c8\u7642\u6cd5\u3092\u7528\u3044\u305f\u81e8\u5e8a\u8a66\u9a13\u304c\u73fe\u5728\u9032\u884c\u4e2d\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\uff08WHO\uff09\u306f\u3001\u30b3\u30eb\u30c9\u30fc\u30de\u30923\u3064\u306e\u30bf\u30a4\u30d7\u306b\u5206\u985e\u3057\u3066\u3044\u307e\u3059\uff1a\u5f93\u6765\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u3001\u8131\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u3001\u304a\u3088\u3073\u672a\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u3059\u3079\u3066\u306e\u30bf\u30a4\u30d7\u306f\u60aa\u6027\u3067\u3001\u9ad8\u3044\u518d\u767a\u7387\u3068\u8ee2\u79fb\u7387\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u975e\u982d\u84cb\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u3067\u306f\u8ee2\u79fb\u7387\u304c\u7d0440%\u3067\u3042\u308a\u3001\u8131\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u304c\u6700\u3082\u8ee2\u79fb\u7387\u304c\u9ad8\u304f\u3001\u6700\u3082\u4e88\u5f8c\u304c\u60aa\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n    <a href=\"\/nipt\/currarino\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u30ab\u30e9\u30ea\u30fc\u30ce\u75c7\u5019\u7fa4\uff08Currarino Syndrome\uff09 <\/div>\n          <div class=\"blog-card-excerpt\">\u30ab\u30e9\u30ea\u30fc\u30ce\u75c7\u5019\u7fa4\u306f\u3001\u4ed9\u9aa8\u7570\u5e38\u3001\u4ed9\u9aa8\u524d\u816b\u760d\u3001\u809b\u9580\u76f4\u8178\u5947\u5f62\u3092\u7279\u5fb4\u3068\u3059\u308b\u7a00\u306a\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u305d\u306e\u767a\u75c7\u30e1\u30ab\u30cb\u30ba\u30e0\u3001\u81e8\u5e8a\u75c7\u72b6\u3001\u753b\u50cf\u30fb\u907a\u4f1d\u5b50...<\/div>\n      <\/div>\n    <\/a>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%B0%86%E6%9D%A5%E3%81%AE%E8%A6%8B%E9%80%9A%E3%81%97\"><\/span>\u5c06\u6765\u306e\u898b\u901a\u3057<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u307e\u308c\u306a\u60aa\u6027\u816b\u760d\u3067\u3001\u305d\u306e\u4e88\u5f8c\u306f\u816b\u760d\u306e\u4f4d\u7f6e\u3084\u5207\u9664\u53ef\u80fd\u6027\u3001\u60a3\u8005\u306e\u5e74\u9f62\u3001\u8ee2\u79fb\u306e\u6709\u7121\u3001\u307e\u305f\u306f\u8131\u5206\u5316\u306e\u6709\u7121\u306a\u3069\u3001\u3044\u304f\u3064\u304b\u306e\u91cd\u8981\u306a\u8981\u56e0\u306b\u4f9d\u5b58\u3057\u307e\u3059\u3002\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u6210\u9577\u304c\u9045\u3044\u3053\u3068\u304c\u591a\u3044\u305f\u3081\u3001\u65e9\u671f\u306b\u8a3a\u65ad\u3059\u308b\u306e\u304c\u96e3\u3057\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u816b\u760d\u304c\u767a\u898b\u3055\u308c\u308b\u3068\u3001\u305d\u306e\u5927\u304d\u3055\u3084\u624b\u8853\u3067\u3069\u308c\u3060\u3051\u5207\u9664\u3067\u304d\u308b\u304b\u304c\u4e88\u5f8c\u3092\u6c7a\u5b9a\u3059\u308b\u5927\u304d\u306a\u8981\u56e0\u3068\u306a\u308a\u307e\u3059\u3002357\u4f8b\u306e\u810a\u690e\u30b3\u30eb\u30c9\u30fc\u30de\u306b\u95a2\u3059\u308b\u7814\u7a76\u3067\u306f\u30013\u5e74\u30015\u5e74\u300110\u5e74\u306e\u5168\u4f53\u751f\u5b58\u7387\u306f\u305d\u308c\u305e\u308c80.5%\u300168.4%\u300139.2%\u3067\u3042\u308a\u3001\u75c5\u6c17\u7279\u7570\u7684\u751f\u5b58\u7387\u306f89.0%\u300180.9%\u300160.1%\u3067\u3057\u305f\u3002\u5168\u4f53\u751f\u5b58\u7387\u306f\u3001\u975e\u624b\u8853\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u3001\u8ee2\u79fb\u304c\u3042\u308b\u60a3\u8005\u3001\u307e\u305f\u306f60\u6b73\u4ee5\u4e0a\u306e\u60a3\u8005\u3067\u6709\u610f\u306b\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/24156031_s.jpg\" alt=\"\u5b50\u3069\u3082\u3092\u611b\u3055\u306a\u3044\u3068\" class=\"wp-image-87708\"\/><\/figure><\/div>\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u30b3\u30eb\u30c9\u30fc\u30de\u306b\u306f\u3044\u304f\u3064\u304b\u306e\u7a2e\u985e\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u7279\u306b\u810a\u690e\u306b\u767a\u751f\u3059\u308b\u8131\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u4e88\u5f8c\u306f\u975e\u5e38\u306b\u60aa\u3044\u3067\u3059\u3002\u4f8b\u3048\u3070\u3001\u8131\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u306e\u60a3\u8005\u306e\u5168\u4f53\u751f\u5b58\u671f\u9593\u306f\u7d0416\u30f6\u6708\u3057\u304b\u3042\u308a\u307e\u305b\u3093\u3002\u3055\u3089\u306b\u3001SMARCB1\/INI1\u907a\u4f1d\u5b50\u306e\u55aa\u5931\u304c\u7279\u5fb4\u7684\u306a\u672a\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u5f93\u6765\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u3068\u6bd4\u8f03\u3057\u3066\u4e88\u5f8c\u304c\u60aa\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u5f93\u6765\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u306b\u95a2\u3057\u3066\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u907a\u4f1d\u7684\u8981\u56e0\u304c\u9032\u884c\u81ea\u7531\u751f\u5b58\u671f\u9593\uff08PFS\uff09\u3092\u4e88\u6e2c\u3059\u308b\u305f\u3081\u306b\u7279\u5b9a\u3055\u308c\u3066\u304a\u308a\u3001\u786c\u819c\u3078\u306e\u4fb5\u5165\u304c\u9032\u884c\u3059\u308b\u3053\u3068\u3067\u4e88\u5f8c\u304c\u60aa\u5316\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u6cbb\u7642\u306b\u306f\u8ab2\u984c\u304c\u3042\u308b\u3082\u306e\u306e\u3001\u624b\u8853\u6280\u8853\u3084\u653e\u5c04\u7dda\u6cbb\u7642\u3001\u5206\u5b50\u6cbb\u7642\u306e\u9032\u6b69\u306b\u3088\u308a\u3001\u591a\u304f\u306e\u60a3\u8005\u306e\u4e88\u5f8c\u306f\u6539\u5584\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u53ef\u80fd\u306a\u9650\u308a\u7a4d\u6975\u7684\u306a\u624b\u8853\u306b\u3088\u308b\u5207\u9664\u304c\u6700\u3082\u91cd\u8981\u306a\u4e88\u5f8c\u56e0\u5b50\u3067\u3059\u304c\u3001\u8131\u5206\u5316\u578b\u3084\u672a\u5206\u5316\u578b\u30b3\u30eb\u30c9\u30fc\u30de\u306a\u3069\u306e\u653b\u6483\u7684\u306a\u30b5\u30d6\u30bf\u30a4\u30d7\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u6cbb\u7642\u306f\u8907\u96d1\u306b\u306a\u308a\u3001\u751f\u5b58\u7387\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u8907\u96d1\u3055\u3092\u8003\u616e\u3059\u308b\u3068\u3001\u5c02\u9580\u7684\u306a\u533b\u7642\u6a5f\u95a2\u3067\u306e\u591a\u8077\u7a2e\u30c1\u30fc\u30e0\u306b\u3088\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u6cbb\u7642\u304c\u3001\u6700\u826f\u306e\u7d50\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u306f\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E3%82%82%E3%81%A3%E3%81%A8%E7%9F%A5%E3%82%8A%E3%81%9F%E3%81%84%E6%96%B9%E3%81%B8\"><\/span>\u3082\u3063\u3068\u77e5\u308a\u305f\u3044\u65b9\u3078<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>\u3010\u8c4a\u5bcc\u306a\u60c5\u5831\u30fb\u82f1\u8a9e\u3011<a href=\"https:\/\/www.chordomafoundation.org\/understanding-chordoma\/\">Chordoma Foundation<\/a><\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%BC%95%E7%94%A8%E6%96%87%E7%8C%AE\"><\/span>\u5f15\u7528\u6587\u732e<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/doi.org\/10.3390\/jcm10051054\">Barber, S. M., Sadrameli, S. S., Lee, J. J., Fridley, J. S., Teh, B. S., Oyelese, A. A., Telfeian, A. E., &amp; Gokaslan, Z. L. (2021). Chordoma\u2014Current understanding and modern treatment paradigms. <em>Journal of Clinical Medicine<\/em>, <em>10<\/em>(5), 1054. https:\/\/doi.org\/10.3390\/jcm10051054<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.5858\/arpa.2020-0258-RA\">Ulici, V., &amp; Hart, J. (2022). Chordoma. <em>Archives of Pathology &amp; Laboratory Medicine<\/em>, <em>146<\/em>(3), 386\u2013395. https:\/\/doi.org\/10.5858\/arpa.2020-0258-RA<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.currproblcancer.2021.100771\">Wedekind, M. F., Widemann, B. C., &amp; Cote, G. (2021). Chordoma: Current status, problems, and future directions. <em>Current Problems in Cancer<\/em>, <em>45<\/em>(4), 100771. https:\/\/doi.org\/10.1016\/j.currproblcancer.2021.100771<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1038\/s41467-023-37593-8\">Sharifnia, T., Wawer, M. J., Goodale, A., Lee, Y., Kazachkova, M., Dempster, J. M., Muller, S., Levy, J., Freed, D. M., Sommer, J., Kalfon, J., Vazquez, F., Hahn, W. C., Root, D. E., Clemons, P. A., &amp; Schreiber, S. L. (2023). Mapping the landscape of genetic dependencies in chordoma. <em>Nature Communications<\/em>, <em>14<\/em>(1), 1933. https:\/\/doi.org\/10.1038\/s41467-023-37593-8<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1016\/j.bbcan.2022.188796\">Karele, E. N., &amp; Paze, A. N. (2022). Chordoma: To know means to recognize. <em>Biochimica et Biophysica Acta (BBA) &#8211; Reviews on Cancer<\/em>, <em>1877<\/em>(5), 188796. https:\/\/doi.org\/10.1016\/j.bbcan.2022.188796<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/omim.org\/entry\/215400\">Online Mendelian Inheritance in Man. (Last updated November 2013 by Ada Hamosh). Retreived from https:\/\/omim.org\/entry\/215400<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1093\/nar\/gkae974\">Perez, G., Barber, G. P., Benet-Pages, A., Casper, J., Clawson, H., Diekhans, M., Fischer, C., Gonzalez, J. N., Hinrichs, A. S., Lee, C. M., Nassar, L. R., Raney, B. J., Speir, M. L., van Baren, M. J., Vaske, C. J., Haussler, D., Kent, W. J., &amp; Haeussler, M. (2024). The UCSC Genome Browser database: 2025 update. Nucleic Acids Research, gkae974. https:\/\/doi.org\/10.1093\/nar\/gkae974<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1093\/nar\/gkad1049\">Harrison, P. W., Amode, M. R., Austine-Orimoloye, O., Azov, A. G., Barba, M., Barnes, I., Becker, A., Bennett, R., Berry, A., Bhai, J., Bhurji, S. K., Boddu, S., Branco Lins, P. R., Brooks, L., Budhanuru Ramaraju, S., Campbell, L. I., Carbajo Martinez, M., Charkhchi, M., Chougule, K., \u2026 Yates, A. D. (2024). Ensembl 2024. Nucleic Acids Research, 52(D1), D891\u2013D899. https:\/\/doi.org\/10.1093\/nar\/gkad1049<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41586-021-03819-2\" target=\"_blank\" rel=\"noreferrer noopener\">Jumper, J <em>et al<\/em>. Highly accurate protein structure prediction with AlphaFold. <em>Nature<\/em> (2021)<\/a>.<\/li>\n\n\n\n<li><a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkab1061\/6430488\" target=\"_blank\" rel=\"noreferrer noopener\">Varadi, M <em>et al<\/em>. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models. <em>Nucleic Acids Research <\/em>(2021)<\/a>.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081\u30b3\u30eb\u30c9\u30fc\u30de\u306f\u3001\u810a\u7d22\u3068\u3044\u3046&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/chordoma\/\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":101,"featured_media":88030,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[58],"tags":[33,43,49],"class_list":["post-83505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genetic-disorder","tag-symptom","tag-gene","tag-genetic-disease"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/83505","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/101"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=83505"}],"version-history":[{"count":22,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/83505\/revisions"}],"predecessor-version":[{"id":109785,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/83505\/revisions\/109785"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/88030"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=83505"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=83505"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=83505"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}