{"id":83594,"date":"2024-11-15T15:56:04","date_gmt":"2024-11-15T06:56:04","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/?p=83594"},"modified":"2025-08-25T09:34:58","modified_gmt":"2025-08-25T00:34:58","slug":"alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/","title":{"rendered":"Alpha-thalassemia\/\u77e5\u7684\u969c\u5bb3\u75c7\u5019\u7fa4\uff08ATR-16\u75c7\u5019\u7fa4\uff09 &#8211; 16p13\u9818\u57df\u95a2\u9023"},"content":{"rendered":"\n<div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\"><h2 style=\"margin-top:1rem;\">\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081<\/h2><p>ATR-16\u75c7\u5019\u7fa4\uff08Alpha Thalassemia Intellectual Disability Syndrome Type 1\uff09\u306f\u3001\u67d3\u8272\u4f5316\u306e\u77ed\u8155\u306e\u672b\u7aef\u9818\u57df\u304c\u6b20\u5931\u3059\u308b\u3053\u3068\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u7a00\u306a\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059\u3002\u3053\u306e\u6b20\u5931\u306b\u3088\u308a\u3001\u03b1\u30b5\u30e9\u30bb\u30df\u30a2\u3068<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u591a\u69d8\u306a\u75c7\u72b6\u304c\u73fe\u308c\u307e\u3059\u3002\u672c\u8a18\u4e8b\u3067\u306f\u3001\u3053\u306e\u75be\u60a3\u306e\u539f\u56e0\u3001\u4e3b\u306a\u7279\u5fb4\u3001\u8a3a\u65ad\u65b9\u6cd5\u3001\u6cbb\u7642\u306e\u53ef\u80fd\u6027\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u3057\u3001\u60a3\u8005\u3068\u305d\u306e\u5bb6\u65cf\u304c\u76f4\u9762\u3059\u308b\u8ab2\u984c\u3068\u30b5\u30dd\u30fc\u30c8\u306e\u91cd\u8981\u6027\u306b\u3064\u3044\u3066\u89e6\u308c\u307e\u3059\u3002<\/p><\/div>\n\n\n\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u76ee\u6b21<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" 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href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E7%96%BE%E6%82%A3%E6%A6%82%E8%A6%81\" >\u75be\u60a3\u6982\u8981<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E4%B8%BB%E3%81%AA%E7%97%87%E7%8A%B6%E3%81%A8%E3%81%9D%E3%81%AE%E8%83%8C%E6%99%AF\" >\u4e3b\u306a\u75c7\u72b6\u3068\u305d\u306e\u80cc\u666f<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E8%A1%80%E6%B6%B2%E7%96%BE%E6%82%A3%EF%BC%9A%CE%B1%E3%82%B5%E3%83%A9%E3%82%BB%E3%83%9F%E3%82%A2\" 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href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E7%97%87%E7%8A%B6%E3%81%AE%E5%A4%9A%E6%A7%98%E6%80%A7%E3%81%A8%E8%A8%BA%E6%96%AD%E3%81%AE%E5%9B%B0%E9%9B%A3%E3%81%95\" >\u75c7\u72b6\u306e\u591a\u69d8\u6027\u3068\u8a3a\u65ad\u306e\u56f0\u96e3\u3055<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E6%B2%BB%E7%99%82%E3%81%A8%E7%AE%A1%E7%90%86%E3%81%AE%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81\" >\u6cbb\u7642\u3068\u7ba1\u7406\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E4%BB%8A%E5%BE%8C%E3%81%AE%E5%B1%95%E6%9C%9B\" >\u4eca\u5f8c\u306e\u5c55\u671b<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/#%E5%BC%95%E7%94%A8%E6%96%87%E7%8C%AE\" >\u5f15\u7528\u6587\u732e<\/a><\/li><\/ul><\/nav><\/div>\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%97%85%E6%B0%97%E3%81%AE%E5%88%A5%E7%A7%B0\"><\/span>\u75c5\u6c17\u306e\u5225\u79f0<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u03b1\u30b5\u30e9\u30bb\u30df\u30a2-<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u75c7\u5019\u7fa4<\/li>\n\n\n\n<li>16\u756a\u67d3\u8272\u4f53\u95a2\u9023\u03b1\u30b5\u30e9\u30bb\u30df\u30a2-<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u75c7\u5019\u7fa4<\/li>\n\n\n\n<li>\u6b20\u5931\u578b\u03b1\u30b5\u30e9\u30bb\u30df\u30a2-<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u75c7\u5019\u7fa4\u30bf\u30a4\u30d71<\/li>\n\n\n\n<li>16\u756a\u67d3\u8272\u4f53\u306b\u95a2\u9023\u3059\u308b\u03b1\u30b5\u30e9\u30bb\u30df\u30a2-<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u75c7\u5019\u7fa4\uff08ATR-16\uff09<\/li>\n\n\n\n<li>\u03b1\u30b5\u30e9\u30bb\u30df\u30a2-<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u75c7\u5019\u7fa4<\/li>\n\n\n\n<li>16\u756a\u67d3\u8272\u4f53\u306b\u95a2\u9023\u3059\u308b\u03b1\u30b5\u30e9\u30bb\u30df\u30a2-<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u75c7\u5019\u7fa4<\/li>\n\n\n\n<li>16\u756a\u67d3\u8272\u4f53\u306b\u95a2\u9023\u3059\u308bATR\u75c7\u5019\u7fa4ATR\u75c7\u5019\u7fa4<\/li>\n\n\n\n<li>\u6b20\u5931\u578b16\u756a\u67d3\u8272\u4f53\u77ed\u8155\u6b20\u5931\u75c7\u5019\u7fa4\uff0816P\u6b20\u5931\u75c7\u5019\u7fa4\uff09<\/li>\n\n\n\n<li>\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3H\u95a2\u9023<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%96%BE%E6%82%A3%E6%A6%82%E8%A6%81\"><\/span>\u75be\u60a3\u6982\u8981<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" width=\"1024\" height=\"20\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/d7656b71bec9a87a4e48c888c820740c-1024x20.png\" alt=\"16p13 \u3000\" class=\"wp-image-90688\"\/><\/figure>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>ATR-16\u75c7\u5019\u7fa4\uff08Alpha Thalassemia Intellectual Disability Syndrome Type 1\uff09\u306f\u3001\u67d3\u8272\u4f5316\u306e\u77ed\u8155\uff08p\uff09\u306e\u672b\u7aef\u9818\u57df\u306b\u3042\u308b\u907a\u4f1d\u7269\u8cea\u304c\u5931\u308f\u308c\u308b\u3053\u3068\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u975e\u5e38\u306b\u7a00\u306a\u907a\u4f1d\u6027\u75be\u60a3\u3067\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u6b20\u5931\u306f\u300c\u6b20\u5931\u6027\u5358\u4f53\u6027\u300d\u3068\u547c\u3070\u308c\u3001\u8907\u6570\u306e\u96a3\u63a5\u3059\u308b\u907a\u4f1d\u5b50\u304c\u4e00\u5ea6\u306b\u5931\u308f\u308c\u308b\u300c\u9023\u7d9a\u907a\u4f1d\u5b50\u75c7\u5019\u7fa4\uff08Contiguous Gene Syndrome\uff09\u300d\u306e\u4e00\u4f8b\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u8840\u6db2\u75be\u60a3\u3084<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u3092\u542b\u3080\u5e45\u5e83\u3044\u75c7\u72b6\u304c\u73fe\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u4eba\u9593\u306e\u7d30\u80de\u306f46\u672c\u306e\u67d3\u8272\u4f53\u3092\u6301\u3061\u3001\u305d\u308c\u305e\u308c\u306b\u907a\u4f1d\u60c5\u5831\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u67d3\u8272\u4f5316\u306f\u305d\u306e\u3046\u3061\u306e1\u672c\u3067\u3001\u77ed\u8155\uff08p\uff09\u3068\u9577\u8155\uff08q\uff09\u306b\u5206\u304b\u308c\u3066\u3044\u307e\u3059\u3002\u672c\u75c7\u5019\u7fa4\u306f\u300116\u756a\u67d3\u8272\u4f53\u306e\u77ed\u815513.3\u9818\u57df\u304b\u3089\u672b\u7aef\uff08\u30c6\u30ed\u30e1\u30a2\uff09\u307e\u3067\u306e\u90e8\u5206\u304c\u6b20\u5931\u3059\u308b\u3053\u3068\u3067\u767a\u751f\u3057\u307e\u3059\u3002\u3053\u306e\u6b20\u5931\u306b\u306f\u3001\u9178\u7d20\u3092\u904b\u3076\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308b\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u306e\u751f\u7523\u3092\u62c5\u3046\u907a\u4f1d\u5b50\uff08HBA1\u3001HBA2\uff09\u304c\u542b\u307e\u308c\u3001\u3055\u3089\u306b\u8133\u3084\u4f53\u306e\u767a\u9054\u306b\u91cd\u8981\u306a\u4ed6\u306e\u907a\u4f1d\u5b50\u3082\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"847\" height=\"500\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/c9463834637ec21cae903d83aeb1945c.png\" alt=\"chromo16\" class=\"wp-image-89937\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%B8%BB%E3%81%AA%E7%97%87%E7%8A%B6%E3%81%A8%E3%81%9D%E3%81%AE%E8%83%8C%E6%99%AF\"><\/span>\u4e3b\u306a\u75c7\u72b6\u3068\u305d\u306e\u80cc\u666f<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>ATR-16\u75c7\u5019\u7fa4\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u81e8\u5e8a\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u4e3b\u306a\u75c7\u72b6\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%A1%80%E6%B6%B2%E7%96%BE%E6%82%A3%EF%BC%9A%CE%B1%E3%82%B5%E3%83%A9%E3%82%BB%E3%83%9F%E3%82%A2\"><\/span>\u8840\u6db2\u75be\u60a3\uff1a\u03b1\u30b5\u30e9\u30bb\u30df\u30a2<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>\u03b1\u30b5\u30e9\u30bb\u30df\u30a2\uff08Alpha Thalassemia\uff09\u306f\u3001\u8d64\u8840\u7403\u5185\u3067\u9178\u7d20\u3092\u904b\u3076\u5f79\u5272\u3092\u62c5\u3046\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u306e\u751f\u7523\u304c\u4f4e\u4e0b\u3059\u308b\u75be\u60a3\u3067\u3059\u3002\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u3092\u69cb\u6210\u3059\u308b\u03b1\u30b0\u30ed\u30d3\u30f3\u9396\u3092\u4f5c\u308bHBA1\u304a\u3088\u3073HBA2\u907a\u4f1d\u5b50\u304c\u67d3\u8272\u4f5316\u306b\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u306e\u907a\u4f1d\u5b50\u304c1\u3064\u6b20\u3051\u308b\u3068\u8efd\u5ea6\u306e\u03b1\u30b5\u30e9\u30bb\u30df\u30a2\uff08\u03b1\u30b5\u30e9\u30bb\u30df\u30a2\u30fb\u30c8\u30ec\u30a4\u30c8\uff09\u304c\u767a\u751f\u3057\u3001\u307b\u3068\u3093\u3069\u75c7\u72b6\u306f\u73fe\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u4e21\u65b9\u306e\u907a\u4f1d\u5b50\u304c\u5927\u304d\u304f\u6b20\u640d\u3059\u308b\u5834\u5408\u306b\u306f\u3001\u8d64\u8840\u7403\u304c\u5c0f\u3055\u304f\uff08\u5c0f\u7403\u6027\uff09\u3001\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u91cf\u304c\u4f4e\u3044\uff08\u4f4e\u8272\u7d20\u6027\uff09\u72b6\u614b\u3068\u306a\u308a\u3001\u4e2d\u7a0b\u5ea6\u306e\u8ca7\u8840\u3092\u5f15\u304d\u8d77\u3053\u3059HbH\u75c5\u304c\u751f\u3058\u307e\u3059\u3002<\/p>\n\n\n\n<p>HbH\u75c5\u3067\u306f\u3001\u8d64\u8840\u7403\u306e\u5bff\u547d\u304c\u77ed\u304f\u306a\u308b\u305f\u3081\u3001\u60a3\u8005\u306f\u75b2\u52b4\u611f\u3001\u606f\u5207\u308c\u3001\u982d\u75db\u3001\u3081\u307e\u3044\u3068\u3044\u3063\u305f\u75c7\u72b6\u3092\u7d4c\u9a13\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u591a\u304f\u306e\u5834\u5408\u3001\u75c7\u72b6\u306f\u5b89\u5b9a\u3057\u3066\u304a\u308a\u3001\u901a\u5e38\u306e\u5bff\u547d\u3092\u4fdd\u3064\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002\u3088\u308a\u91cd\u5ea6\u306e\u30b1\u30fc\u30b9\u3067\u306f\u3001\u8f38\u8840\u3084\u9244\u904e\u5270\u75c7\u306e\u6cbb\u7642\uff08\u9244\u30ad\u30ec\u30fc\u30c8\u7642\u6cd5\uff09\u304c\u5fc5\u8981\u306b\u306a\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n    <a href=\"\/nipt\/citrullinemia-type-1-overview\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">\u30b7\u30c8\u30eb\u30ea\u30f3\u8840\u75c71\u578b\uff08\u30a2\u30eb\u30ae\u30cb\u30ce\u30b3\u30cf\u30af\u9178\u5408\u6210\u9175\u7d20\u6b20\u640d\u75c7\uff09\u3010ASS1\u3011 <\/div>\n          <div class=\"blog-card-excerpt\">\u30b7\u30c8\u30eb\u30ea\u30f3\u8840\u75c71\u578b\uff08Citrullinemia Type I\uff09\u306f\u3001\u5c3f\u7d20\u56de\u8def\u306e\u7570\u5e38\u306b\u3088\u308a\u30a2\u30f3\u30e2\u30cb\u30a2\u304c\u4f53\u5185\u306b\u84c4\u7a4d\u3059\u308b\u307e\u308c\u306a\u75c5\u6c17\u3067\u3059\u3002\u539f\u56e0\u30fb\u75c7\u72b6\u30fb...<\/div>\n      <\/div>\n    <\/a>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%9F%A5%E7%9A%84%E9%9A%9C%E5%AE%B3%E3%81%A8%E7%99%BA%E9%81%94%E9%81%85%E5%BB%B6\"><\/span>\u77e5\u7684\u969c\u5bb3\u3068\u767a\u9054\u9045\u5ef6<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u306f\u3001\u672c\u75c7\u5019\u7fa4\u306e\u3082\u3046\u4e00\u3064\u306e\u4ee3\u8868\u7684\u306a\u7279\u5fb4\u3067\u3059\u3002\u6b20\u5931\u3057\u305f\u907a\u4f1d\u7269\u8cea\u306e\u4e2d\u306b\u306f\u8133\u306e\u767a\u9054\u306b\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u7d50\u679c\u3001\u8efd\u5ea6\u304b\u3089\u4e2d\u7a0b\u5ea6\u306e<a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/why-premium-plan\/\">\u77e5\u7684\u969c\u5bb3<\/a>\u304c\u767a\u751f\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u306f\u3001\u5b66\u7fd2\u80fd\u529b\u306e\u9045\u308c\u3001\u8a00\u8a9e\u767a\u9054\u306e\u9045\u308c\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u767a\u4f5c\uff08\u3066\u3093\u304b\u3093\uff09\u3092\u4f34\u3046\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u5e7c\u5150\u671f\u306b\u306f\u3001\u6b69\u884c\u3084\u8a00\u8a9e\u80fd\u529b\u306e\u767a\u9054\u9045\u5ef6\u304c\u76ee\u7acb\u3064\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u65e9\u671f\u4ecb\u5165\u3068\u3057\u3066\u8a00\u8a9e\u7642\u6cd5\u3084\u7279\u5225\u652f\u63f4\u6559\u80b2\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u5b50\u3069\u3082\u306e\u6210\u9577\u3092\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E8%BA%AB%E4%BD%93%E7%9A%84%E7%89%B9%E5%BE%B4%E3%81%A8%E6%88%90%E9%95%B7%E9%81%85%E5%BB%B6\"><\/span>\u8eab\u4f53\u7684\u7279\u5fb4\u3068\u6210\u9577\u9045\u5ef6<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\n\n\n<p>ATR-16\u75c7\u5019\u7fa4\u306e\u60a3\u8005\u306b\u306f\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u8eab\u4f53\u7684\u7279\u5fb4\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5c0f\u982d\u75c7\uff08\u982d\u56f2\u304c\u901a\u5e38\u3088\u308a\u5c0f\u3055\u3044\uff09<\/li>\n\n\n\n<li>\u7279\u5fb4\u7684\u306a\u9854\u8c8c\uff08\u76ee\u304c\u96e2\u308c\u3066\u3044\u308b\u3001\u9f3b\u6839\u304c\u5e83\u3044\u3001\u5c0f\u3055\u3044\u8033\u306a\u3069\uff09<\/li>\n\n\n\n<li>\u5185\u53cd\u8db3\uff08\u30af\u30e9\u30d6\u30d5\u30c3\u30c8\uff09<\/li>\n\n\n\n<li>\u7537\u5150\u3067\u306f\u505c\u7559\u7cbe\u5de3\u3084\u5c3f\u9053\u4e0b\u88c2\u306a\u3069\u306e\u751f\u6b96\u5668\u7570\u5e38<\/li>\n<\/ul>\n\n\n\n<p>\u307e\u305f\u3001\u6210\u9577\u9045\u5ef6\u306b\u3088\u308a\u3001\u8eab\u9577\u304c\u5e74\u9f62\u306b\u6bd4\u3079\u3066\u4f4e\u3044\u3053\u3068\u3082\u4e00\u822c\u7684\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u75c7\u72b6\u306f\u3001\u6b20\u5931\u306e\u7bc4\u56f2\u304c\u5e83\u304c\u308b\u307b\u3069\u91cd\u75c7\u5316\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/31510744_s.jpg\" alt=\"\u7d46\u5275\u818f\" class=\"wp-image-88803\"\/><\/figure><\/div>\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E7%97%87%E7%8A%B6%E3%81%AE%E5%A4%9A%E6%A7%98%E6%80%A7%E3%81%A8%E8%A8%BA%E6%96%AD%E3%81%AE%E5%9B%B0%E9%9B%A3%E3%81%95\"><\/span>\u75c7\u72b6\u306e\u591a\u69d8\u6027\u3068\u8a3a\u65ad\u306e\u56f0\u96e3\u3055<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>ATR-16\u75c7\u5019\u7fa4\u306f\u75c7\u72b6\u306e\u5e45\u5e83\u3055\u3068\u500b\u4eba\u5dee\u304c\u5927\u304d\u3044\u3053\u3068\u304c\u7279\u5fb4\u3067\u3059\u3002\u3053\u306e\u591a\u69d8\u6027\u306f\u3001\u67d3\u8272\u4f5316\u306e\u6b20\u5931\u7bc4\u56f2\u304c\u500b\u3005\u306e\u60a3\u8005\u3067\u7570\u306a\u308b\u3053\u3068\u306b\u8d77\u56e0\u3057\u3066\u3044\u307e\u3059\u3002\u6b20\u5931\u304c\u5927\u304d\u3044\u5834\u5408\u3001\u75c7\u72b6\u304c\u3088\u308a\u91cd\u304f\u306a\u308b\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u306e\u6b20\u5931\u306e\u7d44\u307f\u5408\u308f\u305b\u304c\u75c7\u72b6\u306e\u5185\u5bb9\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u4e88\u6e2c\u306f\u56f0\u96e3\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u8a3a\u65ad\u306b\u306f\u3001\u67d3\u8272\u4f53\u691c\u67fb\u3084\u907a\u4f1d\u5b50\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002\u7279\u306b\u3001\u8d64\u8840\u7403\u306e\u7570\u5e38\u3084\u767a\u9054\u9045\u5ef6\u304c\u898b\u3089\u308c\u308b\u5834\u5408\u306b\u306f\u3001\u3053\u308c\u3089\u306e\u691c\u67fb\u304c\u884c\u308f\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002\u307e\u305f\u3001\u89aa\u304c\u5747\u8861\u578b\u67d3\u8272\u4f53\u8ee2\u5ea7\u3092\u6301\u3063\u3066\u3044\u308b\u5834\u5408\u3001\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E6%B2%BB%E7%99%82%E3%81%A8%E7%AE%A1%E7%90%86%E3%81%AE%E3%82%A2%E3%83%97%E3%83%AD%E3%83%BC%E3%83%81\"><\/span>\u6cbb\u7642\u3068\u7ba1\u7406\u306e\u30a2\u30d7\u30ed\u30fc\u30c1<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>ATR-16\u75c7\u5019\u7fa4\u306b\u306f\u6839\u672c\u7684\u306a\u6cbb\u7642\u6cd5\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u75c7\u72b6\u306e\u7ba1\u7406\u3092\u76ee\u7684\u3068\u3057\u305f\u6cbb\u7642\u304c\u884c\u308f\u308c\u307e\u3059\u3002\u533b\u5e2b\u3084\u5c02\u9580\u5bb6\u306e\u30c1\u30fc\u30e0\u306b\u3088\u308b\u7dcf\u5408\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u91cd\u8981\u3067\u3059\u3002\u6cbb\u7642\u306e\u4e3b\u306a\u30dd\u30a4\u30f3\u30c8\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u65e9\u671f\u4ecb\u5165<\/strong>: \u8a00\u8a9e\u7642\u6cd5\u3084\u7279\u5225\u652f\u63f4\u6559\u80b2\u3092\u901a\u3058\u3066\u3001\u767a\u9054\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u8840\u6db2\u75be\u60a3\u306e\u7ba1\u7406<\/strong>: \u8efd\u5ea6\u306e\u30b1\u30fc\u30b9\u3067\u306f\u6cbb\u7642\u304c\u4e0d\u8981\u306a\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u91cd\u5ea6\u306e\u8ca7\u8840\u3067\u306f\u8f38\u8840\u3084\u9244\u904e\u5270\u75c7\u306e\u7ba1\u7406\u304c\u5fc5\u8981\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u5fc3\u7406\u7684\u30fb\u793e\u4f1a\u7684\u652f\u63f4<\/strong>: \u5bb6\u65cf\u3084\u60a3\u8005\u304cATR-16\u75c7\u5019\u7fa4\u3068\u5411\u304d\u5408\u3046\u305f\u3081\u306e\u652f\u63f4\u304c\u91cd\u8981\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/24156031_s.jpg\" alt=\"\u5b50\u3069\u3082\u3092\u611b\u3055\u306a\u3044\u3068\" class=\"wp-image-87708\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E4%BB%8A%E5%BE%8C%E3%81%AE%E5%B1%95%E6%9C%9B\"><\/span>\u4eca\u5f8c\u306e\u5c55\u671b<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<p>ATR-16\u75c7\u5019\u7fa4\u306e\u7814\u7a76\u306f\u9032\u884c\u4e2d\u3067\u3042\u308a\u3001\u75c7\u72b6\u3092\u5f15\u304d\u8d77\u3053\u3059\u907a\u4f1d\u5b50\u3084\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e\u304c\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u75be\u60a3\u306b\u95a2\u3059\u308b\u77e5\u8b58\u304c\u6df1\u307e\u308b\u3053\u3068\u3067\u3001\u3088\u308a\u52b9\u679c\u7684\u306a\u8a3a\u65ad\u30fb\u6cbb\u7642\u65b9\u6cd5\u306e\u78ba\u7acb\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u3092\u901a\u3058\u3066\u3001\u5bb6\u65cf\u304cATR-16\u75c7\u5019\u7fa4\u3068\u5411\u304d\u5408\u3044\u3001\u6b21\u4e16\u4ee3\u3078\u306e\u30ea\u30b9\u30af\u3092\u7406\u89e3\u3059\u308b\u52a9\u3051\u3068\u306a\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002\u60a3\u8005\u4e00\u4eba\u3072\u3068\u308a\u306b\u9069\u3057\u305f\u6cbb\u7642\u3068\u30b5\u30dd\u30fc\u30c8\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u304c\u3001\u3053\u306e\u75c7\u5019\u7fa4\u3068\u5171\u306b\u751f\u304d\u308b\u305f\u3081\u306e\u9375\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n    <a href=\"\/nipt\/genetic-counseling\/\" class=\"blog-card\">\n      <div class=\"blog-card-content\">\n          <div class=\"blog-card-title\">NIPT\u306b\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u306f\u5fc5\u8981\uff1f\u5185\u5bb9\u3084\u91cd\u8981\u6027\u3092\u89e3\u8aac <\/div>\n          <div class=\"blog-card-excerpt\">\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001NIPT\u306b\u304a\u3051\u308b\u907a\u4f1d\u30ab\u30a6\u30f3\u30bb\u30ea\u30f3\u30b0\u306e\u5fc5\u8981\u6027\u3084\u5177\u4f53\u7684\u306a\u5185\u5bb9\u306b\u3064\u3044\u3066\u89e3\u8aac\u3057\u307e\u3059\u3002\u691c\u67fb\u3092\u53d7\u3051\u308b\u524d\u306e\u6ce8\u610f\u70b9\u3084\u3001\u5f8c\u6094\u3057\u306a\u3044\u305f\u3081\u306e\u5224\u65ad\u57fa\u6e96...<\/div>\n      <\/div>\n    <\/a>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"%E5%BC%95%E7%94%A8%E6%96%87%E7%8C%AE\"><\/span>\u5f15\u7528\u6587\u732e<span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/2339704\/\">Wilkie, A. O., Buckle, V. J., Harris, P. C., Lamb, J., Barton, N. J., Reeders, S. T., Lindenbaum, R. H., Nicholls, R. D., Barrow, M., &amp; Bethlenfalvay, N. C. (1990). Clinical features and molecular analysis of the alpha thalassemia\/mental retardation syndromes. I. Cases due to deletions involving chromosome band 16p13.3. <em>American journal of human genetics<\/em>, <em>46<\/em>(6), 1112\u20131126.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1086\/302703\">Holinski-Feder, E., Reyniers, E., Uhrig, S., Golla, A., Wauters, J., Kroisel, P., Bossuyt, P., Rost, I., Jedele, K., Zierler, H., Schwab, S., Wildenauer, D., Speicher, M. R., Willems, P. J., Meitinger, T., &amp; Kooy, R. F. (2000). Familial mental retardation syndrome ATR-16 due to an inherited cryptic subtelomeric translocation, t(3;16)(q29;p13.3). <em>American journal of human genetics<\/em>, <em>66<\/em>(1), 16\u201325. https:\/\/doi.org\/10.1086\/302703<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15921166\/\">Gallego, M. S., Zelaya, G., Feliu, A. S., Rossetti, L., Shaffer, L. G., Bailey, K. A., Bacino, C. A., &amp; Barreiro, C. Z. (2005). ATR-16 due to a de novo complex rearrangement of chromosome 16. <em>Hemoglobin<\/em>, <em>29<\/em>(2), 141\u2013150.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1007\/s00439-007-0399-y\">Harteveld, C. L., Kriek, M., Bijlsma, E. K., Erjavec, Z., Balak, D., Phylipsen, M., Voskamp, A., di Capua, E., White, S. J., &amp; Giordano, P. C. (2007). Refinement of the genetic cause of ATR-16. <em>Human genetics<\/em>, <em>122<\/em>(3-4), 283\u2013292. https:\/\/doi.org\/10.1007\/s00439-007-0399-y<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1002\/ajmg.a.32056\">Gibson, W. T., Harvard, C., Qiao, Y., Somerville, M. J., Lewis, M. E., &amp; Rajcan-Separovic, E. (2008). Phenotype-genotype characterization of alpha-thalassemia mental retardation syndrome due to isolated monosomy of 16p13.3. <em>American journal of medical genetics. Part A<\/em>, <em>146A<\/em>(2), 225\u2013232. https:\/\/doi.org\/10.1002\/ajmg.a.32056<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1101\/cshperspect.a011759\">Gibbons R. J. (2012). \u03b1-Thalassemia, mental retardation, and myelodysplastic syndrome. <em>Cold Spring Harbor perspectives in medicine<\/em>, <em>2<\/em>(10), a011759. https:\/\/doi.org\/10.1101\/cshperspect.a011759<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7279195\/\">Babbs C, Brown J, Horsley SW, Slater J, Maifoshie E, Kumar S, Ooijevaar P, Kriek M, Dixon-McIver A, Harteveld CL, Traeger-Synodinos J, Wilkie AOM, Higgs DR, Buckle VJ. ATR-16 syndrome: mechanisms linking monosomy to phenotype. J Med Genet. 2020 Jun;57(6):414-421. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7279195\/<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1038\/ejhg.2014.131\">Traeger-Synodinos, J., Harteveld, C. L., Old, J. M., Petrou, M., Galanello, R., Giordano, P., Angastioniotis, M., De la Salle, B., Henderson, S., May, A., &amp; EMQN haemoglobinopathies best practice meeting (2015). EMQN Best Practice Guidelines for molecular and haematology methods for carrier identification and prenatal diagnosis of the haemoglobinopathies. <em>European journal of human genetics : EJHG<\/em>, <em>23<\/em>(4), 426\u2013437. https:\/\/doi.org\/10.1038\/ejhg.2014.131<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1093\/nar\/gkae974\">Perez, G., Barber, G. P., Benet-Pages, A., Casper, J., Clawson, H., Diekhans, M., Fischer, C., Gonzalez, J. N., Hinrichs, A. S., Lee, C. M., Nassar, L. R., Raney, B. J., Speir, M. L., van Baren, M. J., Vaske, C. J., Haussler, D., Kent, W. J., &amp; Haeussler, M. (2024). The UCSC Genome Browser database: 2025 update. Nucleic Acids Research, gkae974. https:\/\/doi.org\/10.1093\/nar\/gkae974<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/doi.org\/10.1093\/nar\/gkad1049\">Harrison, P. W., Amode, M. R., Austine-Orimoloye, O., Azov, A. G., Barba, M., Barnes, I., Becker, A., Bennett, R., Berry, A., Bhai, J., Bhurji, S. K., Boddu, S., Branco Lins, P. R., Brooks, L., Budhanuru Ramaraju, S., Campbell, L. I., Carbajo Martinez, M., Charkhchi, M., Chougule, K., \u2026 Yates, A. D. (2024). Ensembl 2024. Nucleic Acids Research, 52(D1), D891\u2013D899. https:\/\/doi.org\/10.1093\/nar\/gkad1049<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41586-021-03819-2\" target=\"_blank\" rel=\"noreferrer noopener\">Jumper, J <em>et al<\/em>. Highly accurate protein structure prediction with AlphaFold. <em>Nature<\/em> (2021)<\/a>.<\/li>\n\n\n\n<li><a href=\"https:\/\/academic.oup.com\/nar\/advance-article\/doi\/10.1093\/nar\/gkab1061\/6430488\" target=\"_blank\" rel=\"noreferrer noopener\">Varadi, M <em>et al<\/em>. AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models. <em>Nucleic Acids Research <\/em>(2021)<\/a>.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:16px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"custom-html\"><div class=\"category_btn btn_type_01\">\n<div class=\"category_btn_inner\">\n<p class=\"ttl-txt\">\u598a\u5a20\u4e2d\u306e\u30ea\u30b9\u30af\u7ba1\u7406\u306b<br \/>\nNIPT\u3067\u5b89\u5fc3\u3092<\/p>\n<p class=\"btn\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"\u3053\u306e\u8a18\u4e8b\u306e\u307e\u3068\u3081ATR-16\u75c7\u5019\u7fa4\uff08Al&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/alpha-thalassemia-mental-retardation-syndrome-chromosome-16-related-atr-16-syndrome-16p13\/\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":101,"featured_media":84644,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[58],"tags":[33,43,49,73],"class_list":["post-83594","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genetic-disorder","tag-symptom","tag-gene","tag-genetic-disease","tag-deletion-syndrome"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/83594","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/101"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=83594"}],"version-history":[{"count":9,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/83594\/revisions"}],"predecessor-version":[{"id":112166,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/83594\/revisions\/112166"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/84644"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=83594"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=83594"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=83594"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}