{"id":85503,"date":"2024-11-14T14:19:44","date_gmt":"2024-11-14T05:19:44","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/nipt\/greig-cephalopolysyndactyly-syndrome-gcps\/"},"modified":"2025-08-22T17:25:46","modified_gmt":"2025-08-22T08:25:46","slug":"greig-cephalopolysyndactyly-syndrome-gcps","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/nipt\/greig-cephalopolysyndactyly-syndrome-gcps\/?lang=zh-hans","title":{"rendered":"\u683c\u96f7\u683c\u5934\u9885\u591a\u6307\u75c7\u5019\u7fa4\uff08GCPS\uff09"},"content":{"rendered":"\n<div style=\"border:solid #ffe6e6 0.8rem;background-color: #fff9f9;padding:3% 5%;margin:1rem 0 3rem;\"><h2 style=\"margin-top:1rem;\"> 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src=\"\/nipt\/wp-content\/uploads\/2024\/11\/493e7e7dd14038dd0630d3a9c6d3500c-1024x20.png\" alt=\"7p14.1\u3000GLI3\u3000\" class=\"wp-image-89961\"\/><\/figure><\/div>\n\n\n<p><strong>\u6982\u8ff0<\/strong><strong><br><\/strong> 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\u7531\u4e8eGCPS\u7684\u75c7\u72b6\u4e0e\u5176\u4ed6\u75be\u75c5\u6709\u91cd\u53e0\uff0c\u4ec5\u51ed\u8eab\u4f53\u68c0\u67e5\u5f88\u96be\u505a\u51fa\u660e\u786e\u8bca\u65ad\uff0c\u56e0\u6b64\u5efa\u8bae\u91c7\u7528\u4e34\u5e8a\u8bc4\u4f30\u4e0e\u5206\u5b50\u9057\u4f20\u5b66\u65b9\u6cd5\u76f8\u7ed3\u5408\u7684\u8bca\u65ad\u65b9\u5f0f\u3002\u8bca\u65ad\u65b9\u6cd5\u5305\u62ec\uff1a<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u5206\u5b50\u9057\u4f20\u68c0\u6d4b<\/strong>\uff1a\u786e\u8ba4<strong>GLI3\u57fa\u56e0<\/strong>\u7a81\u53d8\u3002<br><\/li>\n\n\n\n<li><strong>\u4e34\u5e8a\u7279\u5f81<\/strong>\uff1a\u5305\u62ec\u5e7f\u773c\u8ddd\u3001\u5927\u5934\u75c7\u3001\u591a\u6307\u75c7\u548c\u76ae\u80a4\u7c98\u8fde\u7b49\u3002\u901a\u8fc7\u9057\u4f20\u68c0\u6d4b\u786e\u8ba4\u8fd9\u4e9b\u7279\u5f81\u662f\u5426\u7b26\u5408GCPS\u3002<br><\/li>\n\n\n\n<li><strong>\u4ea7\u524d\u8bca\u65ad<\/strong>\uff1a\u53ef\u4ee5\u901a\u8fc7<strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a><\/strong>\u6216<strong>\u8d85\u58f0\u6ce2<\/strong>\u8fdb\u884c\uff0c\u4f46\u8d85\u58f0\u6ce2\u68c0\u6d4b\u5728GCPS\u4e2d\u7684\u53ef\u9760\u6027\u4ecd\u5728\u8bc4\u4f30\u4e2d\u3002<br><\/li>\n<\/ul>\n\n\n\n<p><strong>\u9884\u540e<\/strong><strong><br><\/strong> GCPS\u7684\u9884\u540e\u53d6\u51b3\u4e8e\u75c5\u60c5\u7684\u4e25\u91cd\u7a0b\u5ea6\u548c\u53ca\u65f6\u5e72\u9884\u3002\u8ba4\u77e5\u969c\u788d\u8f83\u4e3a\u7f55\u89c1\uff0c\u8bb8\u591a\u60a3\u8005\u53ef\u4ee5\u8fc7\u4e0a\u5065\u5eb7\u7684\u751f\u6d3b\u3002\u7136\u800c\uff0c\u91cd\u75c7\u60a3\u8005\u53ef\u80fd\u9700\u8981\u8fdb\u884c\u590d\u6742\u7684\u624b\u672f\u6765\u77eb\u6b63\u7578\u5f62\u5e76\u5904\u7406\u76f8\u5173\u95ee\u9898\uff0c\u5982\u9aa8\u9abc\u95ee\u9898\u548c\u5fc3\u810f\u7f3a\u9677\u7b49\u3002<\/p>\n\n\n\n<p>\u65e9\u671f\u8bca\u65ad\u548c\u9057\u4f20\u54a8\u8be2\u53ef\u4ee5\u5e2e\u52a9\u7ba1\u7406\u75be\u75c5\u5e76\u4e3a\u5bb6\u5ead\u63d0\u4f9b\u5fc5\u8981\u7684\u652f\u6301\u3002\u672a\u6765\uff0c\u9176\u66ff\u4ee3\u7597\u6cd5\u548c\u57fa\u56e0\u7597\u6cd5\u53ef\u80fd\u4e3aGCPS\u7684\u6cbb\u7597\u63d0\u4f9b\u65b0\u7684\u89e3\u51b3\u65b9\u6848\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"426\" src=\"\/nipt\/wp-content\/uploads\/2024\/11\/25622460_s.jpg\" alt=\"\u5b89\u5168\u306a\u5834\u6240\u306f\u3053\u306e\u6905\u5b50\u306e\u307f\" class=\"wp-image-87469\"\/><\/figure><\/div>\n\n\n<p><strong>\u53c2\u8003\u6587\u732e<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Biesecker LG, Johnston JJ. Greig Cephalopolysyndactyly Syndrome. GeneReviews\u00ae.<br><\/li>\n\n\n\n<li>Biesecker, L. G. (2008). Greig Cephalopolysyndactyly Syndrome. Orphanet Journal of Rare Diseases.<br><\/li>\n\n\n\n<li>Perez, G., et al. The UCSC Genome Browser Database: 2025 Update. Nucleic Acids Research.<br><\/li>\n\n\n\n<li>Harrison, P. W., et al. Ensembl 2024. Nucleic Acids Research.<br><\/li>\n<\/ol>\n\n\n\n<p><strong>\u66f4\u591a\u5173\u4e8e<\/strong><a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/\">NIPT<\/a>**\uff08\u65e0\u521b\u4ea7\u524d\u68c0\u6d4b\uff09**\u7684\u4fe1\u606f\uff0c\u8bf7\u70b9\u51fb\u8fd9\u91cc\u67e5\u770b\u5173\u4e8e\u9057\u4f20\u7b5b\u67e5\u548c\u6000\u5b55\u671f\u95f4\u98ce\u9669\u7ba1\u7406\u7684\u8be6\u7ec6\u4fe1\u606f\u3002<\/p>\n\n\n\n<div style=\"height:26px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"\u683c\u96f7\u683c\u5934\u9885\u591a\u6307\u75c7\u5019\u7fa4\uff08GCPS\uff09\u662f\u4e00\u79cd\u7f55&#8230;\n <a href=\"https:\/\/www.hiro-clinic.or.jp\/nipt\/greig-cephalopolysyndactyly-syndrome-gcps\/?lang=zh-hans\">\u7d9a\u304d\u3092\u8aad\u3080<\/a>","protected":false},"author":101,"featured_media":88557,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[14],"tags":[],"class_list":["post-85503","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-other-zh-hans"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/85503","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/users\/101"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/comments?post=85503"}],"version-history":[{"count":23,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/85503\/revisions"}],"predecessor-version":[{"id":112090,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/posts\/85503\/revisions\/112090"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media\/88557"}],"wp:attachment":[{"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/media?parent=85503"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/categories?post=85503"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hiro-clinic.or.jp\/nipt\/wp-json\/wp\/v2\/tags?post=85503"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}