{"id":194,"date":"2024-09-14T06:11:45","date_gmt":"2024-09-14T06:11:45","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/regeneration\/?p=194"},"modified":"2024-12-03T05:39:22","modified_gmt":"2024-12-03T05:39:22","slug":"regenerative-medicine-in-ophthalmology","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/regeneration\/regenerative-medicine-in-ophthalmology\/","title":{"rendered":"\u773c\u79d1\u9818\u57df\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642"},"content":{"rendered":"\n\n\n\n

1. \u89d2\u819c\u518d\u751f<\/strong><\/h3>\n\n\n\n

\u89d2\u819c\u306e\u640d\u50b7\u3084\u75be\u60a3\uff08\u89d2\u819c\u6f70\u760d\u3084\u89d2\u819c\u79fb\u690d\u5f8c\u306e\u969c\u5bb3\u306a\u3069\uff09\u306f\u3001\u8996\u529b\u4f4e\u4e0b\u306e\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u518d\u751f\u533b\u7642\u3067\u306f\u3001\u89d2\u819c\u4e0a\u76ae\u5e79\u7d30\u80de\u79fb\u690d<\/span><\/strong>\u3084iPS\u7d30\u80de\u3092\u7528\u3044\u305f\u89d2\u819c\u79fb\u690d<\/span><\/strong>\u304c\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u306b\u3088\u308a\u3001\u5f93\u6765\u306e\u89d2\u819c\u79fb\u690d\u306e\u9650\u754c\u3092\u514b\u670d\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u3001\u81ea\u5bb6\u5e79\u7d30\u80de\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u79fb\u690d\u5f8c\u306e\u62d2\u7d76\u53cd\u5fdc\u3092\u8efd\u6e1b\u3057\u3001\u8996\u529b\u306e\u56de\u5fa9\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

2. \u7db2\u819c\u518d\u751f<\/strong><\/h3>\n\n\n\n

\u7db2\u819c<\/strong>\u306f\u3001\u76ee\u306e\u5965\u306b\u3042\u308b\u5149\u3092\u611f\u77e5\u3059\u308b\u91cd\u8981\u306a\u7d44\u7e54\u3067\u3001\u7db2\u819c\u306e\u640d\u50b7\u3084\u75be\u60a3\uff08\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u3084\u7cd6\u5c3f\u75c5\u6027\u7db2\u819c\u75c7\u306a\u3069\uff09\u306f\u5931\u660e\u306e\u539f\u56e0\u3068\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002iPS\u7d30\u80de\u3084\u5e79\u7d30\u80de\u3092\u5229\u7528\u3057\u305f\u518d\u751f\u533b\u7642\u3067\u306f\u3001\u7db2\u819c\u306e\u6a5f\u80fd\u3092\u56de\u5fa9\u3055\u305b\u308b\u3053\u3068\u304c\u76ee\u6a19\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5e79\u7d30\u80de\u3092\u7db2\u819c\u306b\u79fb\u690d\u3057\u3001\u640d\u50b7\u3057\u305f\u5149\u53d7\u5bb9\u7d30\u80de\u306e\u518d\u751f\u3092\u4fc3\u3059\u3053\u3068\u3067\u3001\u8996\u899a\u306e\u6539\u5584\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n

3. \u8996\u795e\u7d4c\u306e\u518d\u751f<\/strong><\/h3>\n\n\n\n

\u8996\u795e\u7d4c\u304c\u640d\u50b7\u3059\u308b\u3068\u3001\u8996\u529b\u304c\u4f4e\u4e0b\u3059\u308b\u304b\u5931\u308f\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u518d\u751f\u533b\u7642\u3067\u306f\u3001\u5e79\u7d30\u80de\u3092\u5229\u7528\u3057\u3066\u8996\u795e\u7d4c\u306e\u518d\u751f\u3092\u8a66\u307f\u308b\u7814\u7a76\u304c\u9032\u884c\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u7dd1\u5185\u969c<\/strong>\u3084\u5916\u50b7\u6027\u306e\u8996\u795e\u7d4c\u640d\u50b7\u306b\u5bfe\u3059\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

4. \u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u3068\u7db2\u819c\u8272\u7d20\u5909\u6027\u75c7<\/strong><\/h3>\n\n\n\n

\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u3084\u7db2\u819c\u8272\u7d20\u5909\u6027\u75c7\u306a\u3069\u3001\u8996\u529b\u3092\u8457\u3057\u304f\u4f4e\u4e0b\u3055\u305b\u308b\u75be\u60a3\u306b\u5bfe\u3057\u3066\u3082\u518d\u751f\u533b\u7642\u304c\u5fdc\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u75be\u60a3\u3067\u306f\u3001iPS\u7d30\u80de\u3092\u4f7f\u7528\u3057\u3066\u9ec4\u6591\u3084\u7db2\u819c\u306e\u640d\u50b7\u90e8\u5206\u3092\u518d\u751f\u3057\u3001\u8996\u529b\u306e\u56de\u5fa9\u3092\u56f3\u308b\u6cbb\u7642\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u65e5\u672c\u3067\u306f\u3001iPS\u7d30\u80de\u3092\u4f7f\u7528\u3057\u305f\u6cbb\u7642\u304c\u9032\u5c55\u3057\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u306e\u75be\u60a3\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u5fdc\u7528\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n

\n
\"\u76ee\"<\/figure><\/div>\n\n\n

5. \u4eba\u5de5\u7db2\u819c\u3068\u30d0\u30a4\u30aa\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u6280\u8853<\/strong><\/h3>\n\n\n\n

\u4eba\u5de5\u7db2\u819c\u3068\u306f<\/strong><\/h4>\n\n\n\n

\u4eba\u5de5\u7db2\u819c\u306f\u3001\u8996\u529b\u3092\u5931\u3063\u305f\u60a3\u8005\u306e\u7db2\u819c\u6a5f\u80fd\u3092\u88dc\u5b8c\u307e\u305f\u306f\u7f6e\u304d\u63db\u3048\u308b\u305f\u3081\u306b\u958b\u767a\u3055\u308c\u305f\u30c7\u30d0\u30a4\u30b9\u3067\u3059\u3002\u4ee5\u4e0b\u306e2\u3064\u304c\u4e3b\u6d41\u3067\u3059\u3002<\/p>\n\n\n\n

    \n
  1. \u96fb\u5b50\u578b\u4eba\u5de5\u7db2\u819c<\/strong>\n
      \n
    • \u6982\u8981<\/strong>: \u7db2\u819c\u306e\u611f\u5149\u7d30\u80de\u304c\u6a5f\u80fd\u3057\u306a\u3044\u5834\u5408\u306b\u3001\u5149\u3092\u96fb\u6c17\u4fe1\u53f7\u306b\u5909\u63db\u3057\u3066\u8996\u795e\u7d4c\u306b\u4f1d\u3048\u308b\u88c5\u7f6e\u3002<\/li>\n\n\n\n
    • \u4ed5\u7d44\u307f<\/strong>: \u7db2\u819c\u306b\u57cb\u3081\u8fbc\u307e\u308c\u305f\u5fae\u7d30\u306a\u96fb\u6975\u304c\u5149\u523a\u6fc0\u3092\u53d7\u3051\u53d6\u308a\u3001\u8996\u795e\u7d4c\u306b\u4fe1\u53f7\u3092\u9001\u308b\u3053\u3068\u3067\u8996\u899a\u3092\u518d\u69cb\u7bc9\u3002<\/li>\n\n\n\n
    • \u4ee3\u8868\u7684\u306a\u88fd\u54c1<\/strong>:\n
        \n
      • Argus II<\/strong>\uff08\u30a2\u30e1\u30ea\u30ab\u30fbSecond Sight Medical Products\u793e\uff09\uff1a\u5931\u660e\u3057\u305f\u60a3\u8005\u306b\u96fb\u6c17\u523a\u6fc0\u3067\u8996\u899a\u306e\u4e00\u90e8\u3092\u56de\u5fa9\u3055\u305b\u308b\u88c5\u7f6e\u3002<\/li>\n\n\n\n
      • PRIMA System<\/strong>\uff08Pixium Vision\u793e\uff09\uff1a\u7121\u7dda\u578b\u306e\u4eba\u5de5\u7db2\u819c\u3067\u3001\u57cb\u3081\u8fbc\u307f\u306e\u7c21\u4fbf\u6027\u304c\u5411\u4e0a\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n\n\n\n
      • \u751f\u7269\u578b\u4eba\u5de5\u7db2\u819c<\/strong>\n
          \n
        • \u6982\u8981<\/strong>: \u7db2\u819c\u306e\u611f\u5149\u7d30\u80de\u3092\u518d\u751f\u3059\u308b\u305f\u3081\u306b\u3001\u5e79\u7d30\u80de\u3084\u30d0\u30a4\u30aa\u30de\u30c6\u30ea\u30a2\u30eb\u3092\u7528\u3044\u308b\u6280\u8853\u3002<\/li>\n\n\n\n
        • \u4ed5\u7d44\u307f<\/strong>: iPS\u7d30\u80de\u3084ES\u7d30\u80de\uff08\u80da\u6027\u5e79\u7d30\u80de\uff09\u3092\u5229\u7528\u3057\u3066\u3001\u7db2\u819c\u306e\u640d\u50b7\u90e8\u4f4d\u306b\u79fb\u690d\u53ef\u80fd\u306a\u7d30\u80de\u3092\u751f\u6210\u3057\u3001\u6a5f\u80fd\u3092\u88dc\u5b8c\u3002<\/li>\n\n\n\n
        • \u7814\u7a76\u4e8b\u4f8b<\/strong>:\n
            \n
          • \u65e5\u672c\u306e\u7814\u7a76<\/strong>: \u7406\u5316\u5b66\u7814\u7a76\u6240\u3068\u4eac\u90fd\u5927\u5b66\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001iPS\u7d30\u80de\u304b\u3089\u751f\u6210\u3057\u305f\u7db2\u819c\u8272\u7d20\u4e0a\u76ae\u7d30\u80de\uff08RPE\u7d30\u80de\uff09\u306e\u79fb\u690d\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n
            \n\n\n\n

            \u30d0\u30a4\u30aa\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u6280\u8853\u3068\u306f<\/strong><\/h4>\n\n\n\n

            \u30d0\u30a4\u30aa\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u6280\u8853\u306f\u3001\u751f\u4f53\u6750\u6599\u3068\u4eba\u5de5\u6750\u6599\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u81ea\u7136\u306e\u81d3\u5668\u3084\u7d44\u7e54\u306e\u6a5f\u80fd\u3092\u6a21\u5023\u307e\u305f\u306f\u88dc\u5b8c\u3059\u308b\u6280\u8853\u3067\u3059\u3002\u4eba\u5de5\u7db2\u819c\u306b\u304a\u3044\u3066\u3082\u5fdc\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

              \n
            1. \u30d0\u30a4\u30aa\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u7db2\u819c\u306e\u7279\u5fb4<\/strong>\n
                \n
              • \u751f\u4f53\u9069\u5408\u6027\u306e\u3042\u308b\u30dd\u30ea\u30de\u30fc\u3084\u30b3\u30e9\u30fc\u30b2\u30f3\u306a\u3069\u306e\u30d0\u30a4\u30aa\u30de\u30c6\u30ea\u30a2\u30eb\u3092\u57fa\u76e4\u306b\u4f7f\u7528\u3002<\/li>\n\n\n\n
              • \u57cb\u3081\u8fbc\u307f\u578b\u30c7\u30d0\u30a4\u30b9\u306b\u611f\u5149\u6027\u7d30\u80de\u3084\u96fb\u6975\u3092\u7d44\u307f\u8fbc\u3080\u3053\u3068\u3067\u3001\u751f\u4f53\u53cd\u5fdc\u3092\u6700\u5927\u9650\u306b\u6d3b\u304b\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n
              • \u30e1\u30ea\u30c3\u30c8<\/strong>\n
                  \n
                • \u751f\u4f53\u3068\u306e\u9069\u5408\u6027\u304c\u9ad8\u304f\u3001\u514d\u75ab\u62d2\u7d76\u53cd\u5fdc\u306e\u30ea\u30b9\u30af\u3092\u8efd\u6e1b\u3002<\/li>\n\n\n\n
                • \u9577\u671f\u7684\u306a\u5b89\u5b9a\u6027\u3068\u6a5f\u80fd\u6027\u3092\u7dad\u6301\u3002<\/li>\n\n\n\n
                • \u7d44\u7e54\u3068\u7d71\u5408\u3059\u308b\u3053\u3068\u3067\u3001\u81ea\u7136\u306a\u8996\u899a\u6a5f\u80fd\u306e\u518d\u751f\u304c\u53ef\u80fd\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n
                • \u4ee3\u8868\u7684\u306a\u30d7\u30ed\u30b8\u30a7\u30af\u30c8<\/strong>\n
                    \n
                  • \u65e5\u672c\u306e\u53d6\u308a\u7d44\u307f<\/strong>: \u6771\u4eac\u5927\u5b66\u3084\u5927\u962a\u5927\u5b66\u304c\u3001\u751f\u4f53\u7531\u6765\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u3068\u96fb\u5b50\u90e8\u54c1\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u4eba\u5de5\u7db2\u819c\u3092\u7814\u7a76\u3002<\/li>\n\n\n\n
                  • \u6d77\u5916\u306e\u4e8b\u4f8b<\/strong>: \u30a4\u30ae\u30ea\u30b9\u306e\u30aa\u30c3\u30af\u30b9\u30d5\u30a9\u30fc\u30c9\u5927\u5b66\u304c\u3001\u30b7\u30ea\u30b3\u30f3\u30d9\u30fc\u30b9\u306e\u4eba\u5de5\u7db2\u819c\u3068\u30d0\u30a4\u30aa\u30de\u30c6\u30ea\u30a2\u30eb\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u6280\u8853\u3092\u958b\u767a\u4e2d\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n
                    \n\n\n\n

                    \u4eba\u5de5\u7db2\u819c\u3068\u30d0\u30a4\u30aa\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u6280\u8853\u306e\u73fe\u72b6\u3068\u8ab2\u984c<\/strong><\/h4>\n\n\n\n
                    \u73fe\u72b6<\/strong><\/h5>\n\n\n\n
                      \n
                    • \u81e8\u5e8a\u8a66\u9a13<\/strong>: \u96fb\u5b50\u578b\u4eba\u5de5\u7db2\u819c\uff08\u4f8b\uff1aArgus II\uff09\u306f\u65e2\u306b\u4e00\u90e8\u306e\u56fd\u3067\u5546\u696d\u5316\u3055\u308c\u3001\u8996\u899a\u969c\u5bb3\u60a3\u8005\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n
                    • \u57fa\u790e\u7814\u7a76\u306e\u9032\u5c55<\/strong>: iPS\u7d30\u80de\u3092\u7528\u3044\u305f\u518d\u751f\u533b\u7642\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u751f\u7269\u578b\u4eba\u5de5\u7db2\u819c\u304c\u6b21\u4e16\u4ee3\u6280\u8853\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n
                    • \u30d0\u30a4\u30aa\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u306e\u5c0e\u5165<\/strong>: \u751f\u4f53\u6750\u6599\u306e\u6539\u5584\u306b\u3088\u308a\u3001\u9577\u671f\u7684\u306a\u8010\u4e45\u6027\u3068\u6a5f\u80fd\u5411\u4e0a\u304c\u56f3\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n
                      \u8ab2\u984c<\/strong><\/h5>\n\n\n\n
                        \n
                      1. \u96fb\u6e90\u3068\u4fe1\u53f7\u51e6\u7406<\/strong>\n
                          \n
                        • \u96fb\u5b50\u578b\u4eba\u5de5\u7db2\u819c\u306f\u96fb\u529b\u4f9b\u7d66\u306e\u52b9\u7387\u5316\u304c\u5fc5\u8981\u3002<\/li>\n\n\n\n
                        • \u5fae\u7d30\u306a\u96fb\u6975\u3067\u306e\u9ad8\u7cbe\u5ea6\u306a\u4fe1\u53f7\u4f1d\u9054\u304c\u8ab2\u984c\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n
                        • \u7d30\u80de\u79fb\u690d\u6280\u8853<\/strong>\n
                            \n
                          • \u751f\u7269\u578b\u4eba\u5de5\u7db2\u819c\u3067\u306f\u3001\u79fb\u690d\u5f8c\u306e\u7d30\u80de\u306e\u751f\u7740\u7387\u3092\u9ad8\u3081\u308b\u65b9\u6cd5\u304c\u5fc5\u8981\u3002<\/li>\n\n\n\n
                          • \u514d\u75ab\u62d2\u7d76\u53cd\u5fdc\u306e\u56de\u907f\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/li>\n\n\n\n
                          • \u8996\u899a\u306e\u8cea<\/strong>\n
                              \n
                            • \u73fe\u5728\u306e\u4eba\u5de5\u7db2\u819c\u3067\u306f\u3001\u30e2\u30ce\u30af\u30ed\u30fc\u30e0\u306e\u8996\u899a\u3084\u4f4e\u89e3\u50cf\u5ea6\u306e\u8996\u899a\u3057\u304b\u518d\u73fe\u3067\u304d\u306a\u3044\u5834\u5408\u304c\u591a\u3044\u3002<\/li>\n\n\n\n
                            • \u3088\u308a\u81ea\u7136\u306a\u8996\u899a\u518d\u73fe\u3092\u76ee\u6307\u3059\u6280\u8853\u958b\u767a\u304c\u9032\u884c\u4e2d\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n\n\n\n
                              \n\n\n\n

                              \u307e\u3068\u3081<\/h3>\n\n\n\n

                              \u773c\u79d1\u9818\u57df\u306b\u304a\u3051\u308b\u518d\u751f\u533b\u7642\u306f\u3001\u5f93\u6765\u306e\u624b\u8853\u3084\u6cbb\u7642\u3067\u306f\u89e3\u6c7a\u3067\u304d\u306a\u304b\u3063\u305f\u8996\u899a\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u5927\u304d\u306a\u671f\u5f85\u304c\u5bc4\u305b\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u5e79\u7d30\u80de\u3084iPS\u7d30\u80de\u3092\u4f7f\u7528\u3057\u305f\u89d2\u819c\u3084\u7db2\u819c\u306e\u518d\u751f\u6280\u8853\u306f\u3001\u5c06\u6765\u306e\u8996\u529b\u56de\u5fa9\u306b\u5411\u3051\u3066\u975e\u5e38\u306b\u6709\u671b\u3067\u3059\u3002\u4eca\u5f8c\u306e\u6280\u8853\u306e\u9032\u5c55\u306b\u3088\u308a\u3001\u3055\u3089\u306b\u591a\u304f\u306e\u60a3\u8005\u304c\u518d\u751f\u533b\u7642\u306e\u6069\u6075\u3092\u53d7\u3051\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

                              1. \u89d2\u819c\u518d\u751f \u89d2\u819c\u306e\u640d\u50b7\u3084\u75be\u60a3\uff08\u89d2\u819c\u6f70\u760d\u3084\u89d2\u819c\u79fb\u690d\u5f8c\u306e\u969c\u5bb3\u306a\u3069\uff09\u306f\u3001\u8996\u529b\u4f4e\u4e0b\u306e\u539f\u56e0\u3068\u306a\u308a\u307e\u3059\u3002\u518d\u751f\u533b\u7642\u3067\u306f\u3001\u89d2\u819c\u4e0a\u76ae\u5e79\u7d30\u80de\u79fb\u690d\u3084iPS\u7d30\u80de\u3092\u7528\u3044\u305f\u89d2\u819c\u79fb\u690d\u304c\u9032\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u306b\u3088\u308a\u3001\u5f93\u6765\u306e\u89d2\u819c\u79fb\u690d\u306e\u9650\u754c\u3092\u514b\u670d\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u7279\u306b\u3001\u81ea\u5bb6\u5e79\u7d30\u80de\u3092\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u79fb\u690d\u5f8c\u306e\u62d2\u7d76\u53cd\u5fdc\u3092\u8efd\u6e1b\u3057\u3001\u8996\u529b\u306e\u56de\u5fa9\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002 2. \u7db2\u819c\u518d\u751f 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