{"id":319,"date":"2024-11-06T13:06:16","date_gmt":"2024-11-06T13:06:16","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/regeneration\/?p=319"},"modified":"2024-11-14T08:02:40","modified_gmt":"2024-11-14T08:02:40","slug":"renegaraion_mirna","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/regeneration\/renegaraion_mirna\/","title":{"rendered":"\u518d\u751f\u533b\u7642\u3068miRNA"},"content":{"rendered":"\n\n\n\n

\u30de\u30a4\u30af\u30edRNA\u306e\u5f79\u5272<\/h3>\n\n\n\n

\u30de\u30a4\u30af\u30edRNA\u306f\u3001\u7279\u5b9a\u306e\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fcRNA\uff08mRNA\uff09\u306b\u7d50\u5408\u3057\u3066\u305d\u306e\u7ffb\u8a33\u3092\u6291\u5236\u3057\u3001\u6a19\u7684\u3068\u3059\u308b\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u91cf\u3092\u8abf\u6574\u3057\u307e\u3059\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306b\u3088\u308a\u3001miRNA\u306f\u591a\u69d8\u306a\u7d30\u80de\u6d3b\u52d5\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u518d\u751f\u533b\u7642\u306b\u95a2\u9023\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\uff1a<\/p>\n\n\n\n

    \n
  1. \u7d30\u80de\u5206\u5316\u306e\u4fc3\u9032<\/strong>
    miRNA\u306f\u3001\u5e79\u7d30\u80de\u304c\u7279\u5b9a\u306e\u7d44\u7e54\u3084\u7d30\u80de\u306b\u5206\u5316\u3059\u308b\u30d7\u30ed\u30bb\u30b9\u3092\u8abf\u7bc0\u3057\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001miRNA\u304c\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u6291\u5236\u3059\u308b\u3053\u3068\u3067\u3001\u5e79\u7d30\u80de\u304c\u795e\u7d4c\u7d30\u80de\u3084\u5fc3\u7b4b\u7d30\u80de\u306b\u5206\u5316\u3059\u308b\u3088\u3046\u306b\u8a98\u5c0e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/li>\n\n\n\n
  2. \u7d30\u80de\u5897\u6b96\u3068\u751f\u5b58\u306e\u4fc3\u9032<\/strong>
    \u640d\u50b7\u7d44\u7e54\u306e\u518d\u751f\u306b\u306f\u7d30\u80de\u306e\u5897\u6b96\u304c\u5fc5\u8981\u4e0d\u53ef\u6b20\u3067\u3059\u304c\u3001miRNA\u306f\u7d30\u80de\u306e\u5897\u6b96\u3084\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\uff08\u7d30\u80de\u6b7b\uff09\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001\u7d30\u80de\u306e\u751f\u5b58\u7387\u3092\u9ad8\u3081\u308b\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001miRNA\u306f\u640d\u50b7\u3057\u305f\u5fc3\u7b4b\u7d30\u80de\u306e\u56de\u5fa9\u3084\u3001\u795e\u7d4c\u7d30\u80de\u306e\u751f\u5b58\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n\n\n\n
  3. \u708e\u75c7\u306e\u6291\u5236<\/strong>
    \u640d\u50b7\u7d44\u7e54\u3067\u306e\u708e\u75c7\u53cd\u5fdc\u306f\u904e\u5ea6\u3067\u3042\u308b\u3068\u518d\u751f\u3092\u963b\u5bb3\u3057\u307e\u3059\u304c\u3001\u7279\u5b9a\u306emiRNA\u306f\u708e\u75c7\u3092\u6291\u5236\u3059\u308b\u5f79\u5272\u3092\u6301\u3064\u305f\u3081\u3001\u708e\u75c7\u306e\u8abf\u6574\u304c\u53ef\u80fd\u3067\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u708e\u75c7\u53cd\u5fdc\u306b\u3088\u308b\u7d44\u7e54\u306e\u640d\u50b7\u3092\u6291\u3048\u3001\u52b9\u7387\u7684\u306a\u518d\u751f\u3092\u652f\u63f4\u3057\u307e\u3059\u3002<\/li>\n\n\n\n
  4. \u8840\u7ba1\u65b0\u751f\u306e\u4fc3\u9032<\/strong>
    \u8840\u7ba1\u65b0\u751f\uff08\u65b0\u3057\u3044\u8840\u7ba1\u306e\u5f62\u6210\uff09\u306f\u3001\u518d\u751f\u533b\u7642\u306b\u304a\u3044\u3066\u4e0d\u53ef\u6b20\u306a\u30d7\u30ed\u30bb\u30b9\u3067\u3042\u308a\u3001\u9178\u7d20\u3084\u6804\u990a\u306e\u4f9b\u7d66\u3092\u6539\u5584\u3057\u307e\u3059\u3002miRNA\u306f\u3001\u8840\u7ba1\u306e\u6210\u9577\u3084\u518d\u69cb\u7bc9\u306b\u95a2\u4e0e\u3059\u308b\u56e0\u5b50\u306e\u767a\u73fe\u3092\u8abf\u7bc0\u3057\u3001\u65b0\u3057\u3044\u8840\u7ba1\u306e\u5f62\u6210\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u3067\u3001\u518d\u751f\u533b\u7642\u306b\u8ca2\u732e\u3057\u307e\u3059\u3002<\/li>\n<\/ol>\n\n\n\n\n\n\n

    \u518d\u751f\u533b\u7642\u3078\u306e\u5fdc\u7528<\/h3>\n\n\n\n

    miRNA\u306f\u3001\u518d\u751f\u533b\u7642\u306b\u304a\u3044\u3066\u6b21\u306e\u3088\u3046\u306a\u5f62\u3067\u5fdc\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

      \n
    1. \u5e79\u7d30\u80de\u7642\u6cd5\u306e\u88dc\u52a9<\/strong>
      \u5e79\u7d30\u80de\u306bmiRNA\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u7279\u5b9a\u306e\u7d30\u80de\u5206\u5316\u3084\u6210\u9577\u4fc3\u9032\u304c\u8a98\u5c0e\u3055\u308c\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u5fc3\u7b4b\u6897\u585e\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001\u5e79\u7d30\u80de\u306b\u5fc3\u7b4b\u5f62\u6210\u3092\u4fc3\u9032\u3059\u308bmiRNA\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u5fc3\u7b4b\u7d30\u80de\u3078\u306e\u5206\u5316\u304c\u5897\u52a0\u3057\u3001\u5fc3\u81d3\u7d44\u7e54\u306e\u518d\u751f\u304c\u4fc3\u3055\u308c\u307e\u3059\u3002<\/li>\n\n\n\n
    2. \u5275\u50b7\u6cbb\u7652\u306e\u4fc3\u9032<\/strong>
      \u5275\u50b7\u6cbb\u7652\u306b\u95a2\u308f\u308bmiRNA\u306f\u3001\u76ae\u819a\u518d\u751f\u3092\u52a0\u901f\u3055\u305b\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u5275\u50b7\u90e8\u4f4d\u306b\u7279\u5b9a\u306emiRNA\u3092\u6295\u4e0e\u3059\u308b\u3053\u3068\u3067\u3001\u76ae\u819a\u7d30\u80de\u306e\u5897\u6b96\u3068\u5206\u5316\u304c\u4fc3\u9032\u3055\u308c\u3001\u6cbb\u7652\u6642\u9593\u304c\u77ed\u7e2e\u3055\u308c\u307e\u3059\u3002<\/li>\n\n\n\n
    3. \u81d3\u5668\u518d\u751f<\/strong>
      miRNA\u306f\u809d\u81d3\u3084\u814e\u81d3\u306a\u3069\u306e\u81d3\u5668\u518d\u751f\u306b\u3082\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u3001\u809d\u7d30\u80de\u306e\u5897\u6b96\u3084\u5206\u5316\u3092\u4fc3\u3059miRNA\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u809d\u81d3\u518d\u751f\u304c\u4fc3\u9032\u3055\u308c\u3001\u809d\u75be\u60a3\u6cbb\u7642\u306e\u4e00\u74b0\u3068\u3057\u3066\u5229\u7528\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ol>\n\n\n
      \n
      \"\u7814\u7a76\u30a4\u30e1\u30fc\u30b8\"<\/figure><\/div>\n\n\n

      miRNA\u7642\u6cd5\u306e\u8ab2\u984c<\/h3>\n\n\n\n

      \u518d\u751f\u533b\u7642\u306b\u304a\u3051\u308bmiRNA\u306e\u5229\u7528\u306b\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u8ab2\u984c\u3082\u5b58\u5728\u3057\u307e\u3059\u3002<\/p>\n\n\n\n

        \n
      1. \u6a19\u7684\u306e\u6b63\u78ba\u6027<\/strong>\uff1amiRNA\u306f\u591a\u304f\u306e\u907a\u4f1d\u5b50\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u305f\u3081\u3001\u6b63\u78ba\u306a\u6a19\u7684\u907a\u4f1d\u5b50\u3092\u7d5e\u308a\u8fbc\u3080\u3053\u3068\u304c\u96e3\u3057\u304f\u3001\u4e0d\u9069\u5207\u306amiRNA\u304c\u4e88\u671f\u3057\u306a\u3044\u526f\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n
      2. \u6295\u4e0e\u65b9\u6cd5\u306e\u958b\u767a<\/strong>\uff1amiRNA\u3092\u60a3\u90e8\u306b\u52b9\u679c\u7684\u306b\u5c4a\u3051\u308b\u305f\u3081\u306e\u30c7\u30ea\u30d0\u30ea\u30fc\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u304c\u6c42\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u30ca\u30ce\u7c92\u5b50\u3084\u30a6\u30a4\u30eb\u30b9\u30d9\u30af\u30bf\u30fc\u306e\u5229\u7528\u306a\u3069\u3001\u3055\u307e\u3056\u307e\u306a\u6295\u4e0e\u65b9\u6cd5\u304c\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001miRNA\u306e\u5b89\u5b9a\u6027\u3084\u52b9\u679c\u7684\u306a\u5c0e\u5165\u306b\u8ab2\u984c\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n
      3. \u9577\u671f\u7684\u306a\u5b89\u5168\u6027<\/strong>\uff1amiRNA\u7642\u6cd5\u306e\u52b9\u679c\u304c\u9577\u671f\u306b\u308f\u305f\u308b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u305f\u3081\u3001\u305d\u306e\u5b89\u5168\u6027\u306e\u78ba\u8a8d\u304c\u5fc5\u8981\u3067\u3059\u3002\u7279\u306b\u3001\u764c\u5316\u30ea\u30b9\u30af\u3084\u514d\u75ab\u53cd\u5fdc\u306a\u3069\u304c\u61f8\u5ff5\u3055\u308c\u308b\u305f\u3081\u3001\u614e\u91cd\u306a\u8a55\u4fa1\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002<\/li>\n<\/ol>\n\n\n\n\n\n\n

        \u307e\u3068\u3081<\/h3>\n\n\n\n

        \u30de\u30a4\u30af\u30edRNA\u306f\u3001\u518d\u751f\u533b\u7642\u306b\u304a\u3044\u3066\u7d30\u80de\u306e\u5206\u5316\u3084\u6210\u9577\u3092\u8abf\u6574\u3059\u308b\u91cd\u8981\u306a\u8981\u7d20\u3068\u3057\u3066\u3001\u5e79\u7d30\u80de\u7642\u6cd5\u3084\u5275\u50b7\u6cbb\u7652\u3001\u81d3\u5668\u518d\u751f\u306a\u3069\u5e45\u5e83\u3044\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001miRNA\u306e\u6b63\u78ba\u306a\u6a19\u7684\u3084\u52b9\u679c\u7684\u306a\u6295\u4e0e\u65b9\u6cd5\u306e\u958b\u767a\u304c\u6c42\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002miRNA\u7642\u6cd5\u304c\u9032\u5c55\u3059\u308c\u3070\u3001\u518d\u751f\u533b\u7642\u306e\u5206\u91ce\u3067\u3088\u308a\u9ad8\u5ea6\u3067\u52b9\u679c\u7684\u306a\u6cbb\u7642\u304c\u63d0\u4f9b\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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