{"id":361,"date":"2024-11-07T13:56:07","date_gmt":"2024-11-07T13:56:07","guid":{"rendered":"https:\/\/www.hiro-clinic.or.jp\/regeneration\/?p=361"},"modified":"2024-12-05T02:51:01","modified_gmt":"2024-12-05T02:51:01","slug":"ips-cells-characteristics-benefits-applications-challenges","status":"publish","type":"post","link":"https:\/\/www.hiro-clinic.or.jp\/regeneration\/ips-cells-characteristics-benefits-applications-challenges\/","title":{"rendered":"\u518d\u751f\u533b\u7642\u306b\u304a\u3051\u308biPS\u7d30\u80de"},"content":{"rendered":"\n\n\n\n<h3 class=\"wp-block-heading\">iPS\u7d30\u80de\u306e\u7279\u5fb4\u3068\u5229\u70b9<\/h3>\n\n\n\n<p><strong>\u591a\u80fd\u6027<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>iPS\u7d30\u80de\u306f\u3001\u4f53\u5185\u306e\u3042\u3089\u3086\u308b\u7d30\u80de\u306b\u5206\u5316\u3059\u308b\u80fd\u529b\uff08\u591a\u80fd\u6027\uff09\u3092\u6301\u3061\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u76ae\u819a\u3084\u795e\u7d4c\u3001\u5fc3\u7b4b\u306a\u3069\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3084\u81d3\u5668\u306e\u7d30\u80de\u3092\u4f5c\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u81ea\u5df1\u7d30\u80de\u304b\u3089\u4f5c\u6210\u3067\u304d\u308b<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u60a3\u8005\u81ea\u8eab\u306e\u4f53\u7d30\u80de\u304b\u3089iPS\u7d30\u80de\u3092\u4f5c\u308b\u3053\u3068\u3067\u3001\u540c\u3058\u907a\u4f1d\u60c5\u5831\u3092\u6301\u3064\u7d30\u80de\u304c\u4f5c\u6210\u3067\u304d\u308b\u305f\u3081\u3001\u79fb\u690d\u6642\u306e<strong>\u62d2\u7d76\u53cd\u5fdc\u304c\u5c11\u306a\u3044<\/strong>\u3068\u3044\u3046\u5229\u70b9\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u502b\u7406\u7684\u306a\u8ab2\u984c\u304c\u5c11\u306a\u3044<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>ES\u7d30\u80de\u306e\u3088\u3046\u306b\u80da\u3092\u4f7f\u7528\u3059\u308b\u5fc5\u8981\u304c\u306a\u3044\u305f\u3081\u3001\u751f\u547d\u502b\u7406\u306b\u95a2\u3059\u308b\u554f\u984c\u304c\u5c11\u306a\u304f\u3001\u7814\u7a76\u3084\u5fdc\u7528\u306e\u9762\u3067\u306e\u793e\u4f1a\u7684\u53d7\u3051\u5165\u308c\u304c\u9ad8\u3044\u3067\u3059\u3002<\/li>\n<\/ul>\n\n\n\n\n\n\n<h3 class=\"wp-block-heading\">iPS\u7d30\u80de\u306e\u5fdc\u7528\u3068\u518d\u751f\u533b\u7642<\/h3>\n\n\n\n<p>iPS\u7d30\u80de\u306e\u7279\u6027\u3092\u6d3b\u304b\u3057\u3001\u518d\u751f\u533b\u7642\u3067\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u75c5\u6c17\u3084\u640d\u50b7\u306e\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\uff1a<\/p>\n\n\n\n<p><strong>\u795e\u7d4c\u518d\u751f\uff08\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3001\u810a\u9ac4\u640d\u50b7\uff09<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>iPS\u7d30\u80de\u3092\u795e\u7d4c\u7d30\u80de\u306b\u5206\u5316\u3055\u305b\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3084\u810a\u9ac4\u640d\u50b7\u306e\u6cbb\u7642\u306b\u7528\u3044\u308b\u7814\u7a76\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u640d\u50b7\u3057\u305f\u795e\u7d4c\u7d44\u7e54\u3092\u518d\u751f\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u904b\u52d5\u6a5f\u80fd\u3084\u611f\u899a\u306e\u56de\u5fa9\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u5fc3\u81d3\u75c5\u306e\u6cbb\u7642<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5fc3\u7b4b\u7d30\u80de\u306b\u5206\u5316\u3055\u305b\u305fiPS\u7d30\u80de\u3092\u4f7f\u3063\u3066\u3001\u5fc3\u7b4b\u6897\u585e\u5f8c\u306e\u5fc3\u7b4b\u518d\u751f\u3092\u56f3\u308b\u6cbb\u7642\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5fc3\u81d3\u306e\u30dd\u30f3\u30d7\u6a5f\u80fd\u306e\u56de\u5fa9\u3092\u76ee\u6307\u3059\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u7db2\u819c\u518d\u751f\uff08\u8996\u899a\u969c\u5bb3\u306e\u6cbb\u7642\uff09<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>iPS\u7d30\u80de\u304b\u3089\u4f5c\u3089\u308c\u305f\u7db2\u819c\u7d30\u80de\u3092\u4f7f\u3063\u3066\u3001\u52a0\u9f62\u9ec4\u6591\u5909\u6027\u75c7\u306a\u3069\u306e\u8996\u899a\u969c\u5bb3\u3092\u6cbb\u7642\u3059\u308b\u8a66\u307f\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u5931\u660e\u306e\u30ea\u30b9\u30af\u304c\u3042\u308b\u75be\u60a3\u306e\u6cbb\u7642\u306b\u65b0\u305f\u306a\u624b\u6bb5\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u8840\u6db2\u75be\u60a3\uff08\u8ca7\u8840\u3001\u767d\u8840\u75c5\u306a\u3069\uff09\u306e\u6cbb\u7642<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u8840\u6db2\u7d30\u80de\u306b\u5206\u5316\u3055\u305b\u3066\u79fb\u690d\u3059\u308b\u3053\u3068\u3067\u3001\u8840\u6db2\u75be\u60a3\u306e\u6cbb\u7642\u306b\u5f79\u7acb\u3066\u308b\u7814\u7a76\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u9aa8\u9ac4\u79fb\u690d\u304c\u96e3\u3057\u3044\u5834\u5408\u306e\u4ee3\u66ff\u6cbb\u7642\u3068\u3057\u3066\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<p><strong>\u7cd6\u5c3f\u75c5\u306e\u6cbb\u7642<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>iPS\u7d30\u80de\u304b\u3089\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u5206\u6ccc\u3059\u308b\u81b5\u5cf6\u7d30\u80de\u3092\u4f5c\u308a\u51fa\u3057\u30011\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u79fb\u690d\u3059\u308b\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"640\" height=\"427\" src=\"https:\/\/www.hiro-clinic.or.jp\/regeneration\/wp-content\/uploads\/2024\/11\/30584361_s.webp\" alt=\"\u60a9\u3080\u767d\u8863\u7537\u6027\" class=\"wp-image-676\" srcset=\"https:\/\/www.hiro-clinic.or.jp\/regeneration\/wp-content\/uploads\/2024\/11\/30584361_s.webp 640w, https:\/\/www.hiro-clinic.or.jp\/regeneration\/wp-content\/uploads\/2024\/11\/30584361_s-300x200.webp 300w, https:\/\/www.hiro-clinic.or.jp\/regeneration\/wp-content\/uploads\/2024\/11\/30584361_s-485x324.webp 485w\" sizes=\"(max-width: 640px) 100vw, 640px\" \/><\/figure><\/div>\n\n\n<h3 class=\"wp-block-heading\">1. iPS\u7d30\u80de\u306e\u8ab2\u984c<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">(1) \u5b89\u5168\u6027\u306e\u78ba\u4fdd<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u306f\u3001\u4f53\u7d30\u80de\u306b\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u591a\u80fd\u6027\u3092\u6301\u3064\u5e79\u7d30\u80de\u306b\u5909\u5316\u3055\u305b\u307e\u3059\u3002\u3053\u306e\u904e\u7a0b\u306b\u306f\u4ee5\u4e0b\u306e\u5b89\u5168\u6027\u306e\u8ab2\u984c\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>\u816b\u760d\u5316\u306e\u30ea\u30b9\u30af<\/strong><br>iPS\u7d30\u80de\u306f\u5206\u5316\u80fd\u304c\u9ad8\u3044\u53cd\u9762\u3001\u5236\u5fa1\u304c\u96e3\u3057\u3044\u305f\u3081\u3001\u816b\u760d\uff08\u7279\u306b\u5947\u5f62\u816b\uff09\u306e\u5f62\u6210\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n\n\n<li><strong>\u907a\u4f1d\u5b50\u64cd\u4f5c\u306e\u5f71\u97ff<\/strong><br>\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u3084\u30ec\u30f3\u30c1\u30a6\u30a4\u30eb\u30b9\u3092\u7528\u3044\u305f\u907a\u4f1d\u5b50\u5c0e\u5165\u6cd5\u3067\u306f\u3001\u610f\u56f3\u305b\u305a\u907a\u4f1d\u5b50\u304c\u7d44\u307f\u8fbc\u307e\u308c\u3001\u7a81\u7136\u5909\u7570\u304c\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(2) \u5206\u5316\u306e\u5b89\u5b9a\u6027<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u304b\u3089\u7279\u5b9a\u306e\u7d30\u80de\u3084\u7d44\u7e54\u306b\u5206\u5316\u3055\u305b\u308b\u969b\u3001\u5b8c\u5168\u306b\u76ee\u7684\u306e\u7d30\u80de\u306b\u5206\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u96e3\u3057\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u7570\u306a\u308b\u7d30\u80de\u304c\u6df7\u5728\u3059\u308b\u3068\u3001\u6cbb\u7642\u52b9\u679c\u304c\u4f4e\u4e0b\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u4e88\u671f\u305b\u306c\u526f\u4f5c\u7528\u304c\u767a\u751f\u3059\u308b\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(3) \u514d\u75ab\u62d2\u7d76\u53cd\u5fdc<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u306f\u60a3\u8005\u81ea\u8eab\u306e\u7d30\u80de\u304b\u3089\u4f5c\u6210\u3055\u308c\u308b\u5834\u5408\u3001\u514d\u75ab\u62d2\u7d76\u53cd\u5fdc\u304c\u8d77\u3053\u308a\u306b\u304f\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u4ed6\u5bb6\u7531\u6765\u306eiPS\u7d30\u80de\u3092\u4f7f\u7528\u3059\u308b\u5834\u5408\u3001\u514d\u75ab\u53cd\u5fdc\u304c\u554f\u984c\u3068\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(4) \u30b3\u30b9\u30c8\u306e\u9ad8\u3055<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u306e\u4f5c\u6210\u304a\u3088\u3073\u5206\u5316\u306b\u306f\u9ad8\u5ea6\u306a\u6280\u8853\u3068\u8a2d\u5099\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u30b3\u30b9\u30c8\u304c\u975e\u5e38\u306b\u9ad8\u3044\u3053\u3068\u304c\u8ab2\u984c\u3067\u3059\u3002\u3053\u308c\u304c\u60a3\u8005\u8ca0\u62c5\u306b\u76f4\u7d50\u3059\u308b\u305f\u3081\u3001\u5e83\u7bc4\u306a\u666e\u53ca\u3092\u59a8\u3052\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(5) \u898f\u5236\u304a\u3088\u3073\u502b\u7406\u7684\u8ab2\u984c<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u306e\u7814\u7a76\u3068\u81e8\u5e8a\u5fdc\u7528\u306b\u306f\u898f\u5236\u304c\u5fc5\u8981\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u5e79\u7d30\u80de\u7814\u7a76\u5168\u822c\u306b\u95a2\u3057\u3066\u306f\u3001\u751f\u547d\u502b\u7406\u3084\u5b89\u5168\u6027\u306e\u89b3\u70b9\u304b\u3089\u8b70\u8ad6\u304c\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">2. iPS\u7d30\u80de\u306e\u30ea\u30b9\u30af<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">(1) \u816b\u760d\u5316\u306e\u30ea\u30b9\u30af<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u306e\u7121\u5236\u9650\u306a\u5897\u6b96\u80fd\u529b\u306f\u3001\u60aa\u6027\u816b\u760d\u306e\u539f\u56e0\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u7d30\u80de\u6cbb\u7642\u306b\u304a\u3044\u3066\u5927\u304d\u306a\u61f8\u5ff5\u6750\u6599\u3067\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(2) \u611f\u67d3\u30ea\u30b9\u30af<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u306e\u4f5c\u88fd\u304a\u3088\u3073\u57f9\u990a\u904e\u7a0b\u3067\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u304c\u4f34\u3044\u307e\u3059\u3002\u4e0d\u9069\u5207\u306a\u57f9\u990a\u74b0\u5883\u3067\u7d30\u83cc\u3084\u30a6\u30a4\u30eb\u30b9\u306b\u6c5a\u67d3\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(3) \u672a\u719f\u306a\u6280\u8853\u306b\u3088\u308b\u526f\u4f5c\u7528<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u3092\u5229\u7528\u3057\u305f\u6cbb\u7642\u306f\u307e\u3060\u767a\u5c55\u9014\u4e0a\u3067\u3042\u308a\u3001\u6cbb\u7642\u5f8c\u306e\u526f\u4f5c\u7528\u3084\u9577\u671f\u7684\u306a\u30ea\u30b9\u30af\u304c\u5b8c\u5168\u306b\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">3. \u8ab2\u984c\u3068\u30ea\u30b9\u30af\u3092\u514b\u670d\u3059\u308b\u305f\u3081\u306e\u53d6\u308a\u7d44\u307f<\/h3>\n\n\n\n<h4 class=\"wp-block-heading\">(1) 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has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(3) iPS\u7d30\u80de\u30b9\u30c8\u30c3\u30af\u306e\u5229\u7528<\/h4>\n\n\n\n<p>\u514d\u75ab\u62d2\u7d76\u53cd\u5fdc\u3092\u6700\u5c0f\u9650\u306b\u6291\u3048\u308b\u305f\u3081\u3001HLA\u578b\u3092\u4e00\u81f4\u3055\u305b\u305fiPS\u7d30\u80de\u3092\u30b9\u30c8\u30c3\u30af\u3068\u3057\u3066\u4fdd\u5b58\u3057\u3001\u9069\u5207\u306a\u60a3\u8005\u306b\u63d0\u4f9b\u3059\u308b\u53d6\u308a\u7d44\u307f\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(4) \u30b3\u30b9\u30c8\u524a\u6e1b\u306e\u7814\u7a76<\/h4>\n\n\n\n<p>\u52b9\u7387\u7684\u306a\u4f5c\u88fd\u65b9\u6cd5\u3084\u81ea\u52d5\u5316\u6280\u8853\u306e\u958b\u767a\u306b\u3088\u308a\u3001iPS\u7d30\u80de\u6cbb\u7642\u306e\u30b3\u30b9\u30c8\u524a\u6e1b\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">(5) \u898f\u5236\u3068\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306e\u6574\u5099<\/h4>\n\n\n\n<p>iPS\u7d30\u80de\u7814\u7a76\u306e\u9069\u5207\u306a\u898f\u5236\u3092\u78ba\u7acb\u3057\u3001\u6cbb\u7642\u306e\u5b89\u5168\u6027\u3068\u502b\u7406\u6027\u3092\u78ba\u4fdd\u3059\u308b\u52aa\u529b\u304c\u9032\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n\n\n\n<h3 class=\"wp-block-heading\">\u307e\u3068\u3081<\/h3>\n\n\n\n<p>iPS\u7d30\u80de\u306f\u3001\u518d\u751f\u533b\u7642\u306e\u5206\u91ce\u306b\u304a\u3044\u3066\u753b\u671f\u7684\u306a\u6cbb\u7642\u6cd5\u3092\u63d0\u4f9b\u3059\u308b\u53ef\u80fd\u6027\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u591a\u80fd\u6027\u3092\u6d3b\u304b\u3057\u3066\u3001\u5e45\u5e83\u3044\u75be\u60a3\u306e\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u3001\u60a3\u8005\u306e\u8ca0\u62c5\u3092\u8efd\u6e1b\u3059\u308b\u6cbb\u7642\u304c\u958b\u767a\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u4e00\u65b9\u3067\u3001\u5b89\u5168\u6027\u3084\u30b3\u30b9\u30c8\u306e\u9762\u3067\u306e\u8ab2\u984c\u3082\u3042\u308b\u305f\u3081\u3001\u5f15\u304d\u7d9a\u304d\u7814\u7a76\u3068\u6539\u5584\u304c\u5fc5\u8981\u3067\u3059\u3002\u4eca\u5f8c\u3001iPS\u7d30\u80de\u306e\u6280\u8853\u304c\u9032\u5316\u3059\u308b\u3053\u3068\u3067\u3001\u518d\u751f\u533b\u7642\u306e\u666e\u53ca\u3068\u9ad8\u5ea6\u306a\u6cbb\u7642\u306e\u5b9f\u73fe\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>iPS\u7d30\u80de\u306e\u7279\u5fb4\u3068\u5229\u70b9 \u591a\u80fd\u6027 \u81ea\u5df1\u7d30\u80de\u304b\u3089\u4f5c\u6210\u3067\u304d\u308b \u502b\u7406\u7684\u306a\u8ab2\u984c\u304c\u5c11\u306a\u3044 iPS\u7d30\u80de\u306e\u5fdc\u7528\u3068\u518d\u751f\u533b\u7642 iPS\u7d30\u80de\u306e\u7279\u6027\u3092\u6d3b\u304b\u3057\u3001\u518d\u751f\u533b\u7642\u3067\u306f\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u75c5\u6c17\u3084\u640d\u50b7\u306e\u6cbb\u7642\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\uff1a \u795e\u7d4c\u518d\u751f\uff08\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c5\u3001\u810a\u9ac4\u640d\u50b7\uff09 \u5fc3\u81d3\u75c5\u306e\u6cbb\u7642 \u7db2\u819c\u518d\u751f\uff08\u8996\u899a\u969c\u5bb3\u306e\u6cbb\u7642\uff09 \u8840\u6db2\u75be\u60a3\uff08\u8ca7\u8840\u3001\u767d\u8840\u75c5\u306a\u3069\uff09\u306e\u6cbb\u7642 \u7cd6\u5c3f\u75c5\u306e\u6cbb\u7642 1. iPS\u7d30\u80de\u306e\u8ab2\u984c (1) \u5b89\u5168\u6027\u306e\u78ba\u4fdd iPS\u7d30\u80de\u306f\u3001\u4f53\u7d30\u80de\u306b\u7279\u5b9a\u306e\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3059\u308b\u3053\u3068\u3067\u591a\u80fd\u6027\u3092\u6301\u3064\u5e79\u7d30\u80de\u306b\u5909\u5316\u3055\u305b\u307e\u3059\u3002\u3053\u306e\u904e\u7a0b\u306b\u306f\u4ee5\u4e0b\u306e\u5b89\u5168\u6027\u306e\u8ab2\u984c\u304c\u3042\u308a\u307e\u3059\u3002 (2) \u5206\u5316\u306e\u5b89\u5b9a\u6027 iPS\u7d30\u80de\u304b\u3089\u7279\u5b9a\u306e\u7d30\u80de\u3084\u7d44\u7e54\u306b\u5206\u5316\u3055\u305b\u308b\u969b\u3001\u5b8c\u5168\u306b\u76ee\u7684\u306e\u7d30\u80de\u306b\u5206\u5316\u3055\u305b\u308b\u3053\u3068\u304c\u96e3\u3057\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\u7570\u306a\u308b\u7d30\u80de\u304c\u6df7\u5728\u3059\u308b\u3068\u3001\u6cbb\u7642\u52b9\u679c\u304c\u4f4e\u4e0b\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u4e88\u671f\u305b\u306c\u526f\u4f5c\u7528\u304c\u767a\u751f\u3059\u308b\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002 (3) \u514d\u75ab\u62d2\u7d76\u53cd\u5fdc iPS\u7d30\u80de\u306f\u60a3\u8005\u81ea\u8eab\u306e\u7d30\u80de\u304b\u3089\u4f5c\u6210\u3055\u308c\u308b\u5834\u5408\u3001\u514d\u75ab\u62d2\u7d76\u53cd\u5fdc\u304c\u8d77\u3053\u308a\u306b\u304f\u3044\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u4ed6\u5bb6\u7531\u6765\u306eiPS\u7d30\u80de\u3092\u4f7f\u7528\u3059\u308b\u5834\u5408\u3001\u514d\u75ab\u53cd\u5fdc\u304c\u554f\u984c\u3068\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002 (4) \u30b3\u30b9\u30c8\u306e\u9ad8\u3055 iPS\u7d30\u80de\u306e\u4f5c\u6210\u304a\u3088\u3073\u5206\u5316\u306b\u306f\u9ad8\u5ea6\u306a\u6280\u8853\u3068\u8a2d\u5099\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u30b3\u30b9\u30c8\u304c\u975e\u5e38\u306b\u9ad8\u3044\u3053\u3068\u304c\u8ab2\u984c\u3067\u3059\u3002\u3053\u308c\u304c\u60a3\u8005\u8ca0\u62c5\u306b\u76f4\u7d50\u3059\u308b\u305f\u3081\u3001\u5e83\u7bc4\u306a\u666e\u53ca\u3092\u59a8\u3052\u3066\u3044\u307e\u3059\u3002 (5) \u898f\u5236\u304a\u3088\u3073\u502b\u7406\u7684\u8ab2\u984c iPS\u7d30\u80de\u306e\u7814\u7a76\u3068\u81e8\u5e8a\u5fdc\u7528\u306b\u306f\u898f\u5236\u304c\u5fc5\u8981\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u5e79\u7d30\u80de\u7814\u7a76\u5168\u822c\u306b\u95a2\u3057\u3066\u306f\u3001\u751f\u547d\u502b\u7406\u3084\u5b89\u5168\u6027\u306e\u89b3\u70b9\u304b\u3089\u8b70\u8ad6\u304c\u7d9a\u3044\u3066\u3044\u307e\u3059\u3002 2. iPS\u7d30\u80de\u306e\u30ea\u30b9\u30af (1) \u816b\u760d\u5316\u306e\u30ea\u30b9\u30af iPS\u7d30\u80de\u306e\u7121\u5236\u9650\u306a\u5897\u6b96\u80fd\u529b\u306f\u3001\u60aa\u6027\u816b\u760d\u306e\u539f\u56e0\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u7d30\u80de\u6cbb\u7642\u306b\u304a\u3044\u3066\u5927\u304d\u306a\u61f8\u5ff5\u6750\u6599\u3067\u3059\u3002 (2) \u611f\u67d3\u30ea\u30b9\u30af iPS\u7d30\u80de\u306e\u4f5c\u88fd\u304a\u3088\u3073\u57f9\u990a\u904e\u7a0b\u3067\u611f\u67d3\u75c7\u30ea\u30b9\u30af\u304c\u4f34\u3044\u307e\u3059\u3002\u4e0d\u9069\u5207\u306a\u57f9\u990a\u74b0\u5883\u3067\u7d30\u83cc\u3084\u30a6\u30a4\u30eb\u30b9\u306b\u6c5a\u67d3\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 (3) \u672a\u719f\u306a\u6280\u8853\u306b\u3088\u308b\u526f\u4f5c\u7528 iPS\u7d30\u80de\u3092\u5229\u7528\u3057\u305f\u6cbb\u7642\u306f\u307e\u3060\u767a\u5c55\u9014\u4e0a\u3067\u3042\u308a\u3001\u6cbb\u7642\u5f8c\u306e\u526f\u4f5c\u7528\u3084\u9577\u671f\u7684\u306a\u30ea\u30b9\u30af\u304c\u5b8c\u5168\u306b\u306f\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u305b\u3093\u3002 3. \u8ab2\u984c\u3068\u30ea\u30b9\u30af\u3092\u514b\u670d\u3059\u308b\u305f\u3081\u306e\u53d6\u308a\u7d44\u307f (1) \u65b0\u3057\u3044\u907a\u4f1d\u5b50\u5c0e\u5165\u6280\u8853\u306e\u958b\u767a 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