治療

ED薬　勃起不全　タダラフィル　硬さ　持続力　LINEED

How do you self-diagnose ED (erectile dysfunction)?

A widely used, simple method for assessing erectile dysfunction (ED) through self-diagnosis is the IIEF-5 (International Index of Erectile Function-5) questionnaire. It is a reliable screening tool for assessing erectile function and is used by health care providers. Below is a brief description of how it works. IIEF-5 Questionnaire The IIEF-5 consists of five questions, with a score of 1 to 5 given for each question. By summing these scores, one can self-assess the severity of EDs. Questions Total score and severity of ED Limitations...
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How to deal with the stress of ED (erectile dysfunction)

The stress caused by erectile dysfunction (ED) is considered to be considerable for patients; ED can cause loss of sexual confidence and strained relationships with partners, which often leads to emotional strain. In addition, social stigma and lack of understanding can contribute to the increased stress felt by the patient. For this reason, appropriate support and treatment are important, and a treatment approach that includes psychological aspects is recommended. If the stress and psychological impact of ED (erectile dysfunction) is significant, consultation with a psychosomatic...
ナース関連疾患

Premature Ejaculation and ED Drugs

Premature ejaculation and erectile dysfunction (ED) are both sexual dysfunctions, but they occur through different mechanisms. Nevertheless, there can be an indirect link between them. What is premature ejaculation? Premature ejaculation is a condition in which ejaculation occurs extremely quickly during intercourse, which may involve psychological or neurophysiological factors. In some men, premature ejaculation can result from performance anxiety or sexual tension. What is Erectile Dysfunction (ED)? Erectile dysfunction is the inability to achieve or maintain an erection necessary for adequate sexual activity; causes of...
薬関連疾患

Pulmonary Hypertension and PDE5

Pulmonary Hypertension (PH) is a condition in which the blood pressure in the pulmonary arteries becomes abnormally high, which places an excessive burden on the heart and can eventually lead to heart failure. This condition occurs when the walls of the pulmonary arteries become thickened, stiffened, or narrowed, restricting blood flow. Pulmonary hypertension is characterized by symptoms such as shortness of breath during exercise, chest pain, fatigue, and dizziness. Five-year survival rates for pulmonary arterial hypertension (PAH) vary widely depending on the type of disease...
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What is PDE5?

The PDE5 (phosphodiesterase type 5) enzyme is an important enzyme, especially active in the smooth muscle cells of the penis, responsible for the breakdown of the molecule cGMP (cyclic guanosine monophosphate). cGMP promotes relaxation of vascular smooth muscle and increases blood flow to blood flow, thereby assisting in erection. Below is a more detailed description of the PDE5 enzyme and its biological importance. Role of PDE5 enzymeDegradation of cGMP: PDE5 is responsible for degrading cGMP, which terminates the biological effects of cGMP. cGMP is produced...
バルデナフィルの構造式Other

Structural formula of Vardenafil

Vardenafil (Vardenafil) is a phosphodiesterase type 5 (PDE5) inhibitor, primarily used to treat erectile dysfunction (ED).It is known on the market under brand names such as Levitra and Staxyn. These drugs work by improving blood flow to support an erection. Molecular Structure of Vardenafil The chemical formula of vardenafil is C23H32N6O4S and has the following structural characteristics Sequence of actions Vardenafil, like sildenafil and tadalafil, inhibits the activity of the PDE5 enzyme. This enzyme degrades cGMP in penile tissue. cGMP promotes vasodilation and smooth muscle...
シダラフィルの分子構造Other

Molecular Structure of Cidarafil

Sildenafil (Sildenafil), also known as a phosphodiesterase type 5 (PDE5) inhibitor, is used primarily for the treatment of erectile dysfunction (ED), but also for pulmonary hypertension. This drug is particularly well known under its brand name Viagra. Molecular structure of sildenafil The chemical formula of sildenafil is C₂₂₂H₃₀N₆O₄S and has the following characteristic chemical structure Sequence of actions Sildenafil is known to inhibit the activity of the PDE5 enzyme, which is abundant in penile tissue and is responsible for degrading cGMP (cyclic guanosine monophosphate). cGMP...
タダラフィルの分子構造Other

Molecular structure of tadalafil

Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, widely known by the brand name Cialis. It is used for the treatment of erectile dysfunction (ED) and also for the treatment of pulmonary hypertension. Molecular structure of tadalafil The chemical name for tadalafil is 1,2,3,4-tetrahydro-β-carboline-6-carboxamide, and its official chemical formula is C₂₂H₁₉N₃O₄. This molecule has several characteristic chemical structures: Molecular Mechanism of Action Tadalafil inhibits the PDE5 enzyme from degrading cGMP (cyclic guanosine monophosphate). cGMP aids erection by promoting smooth muscle relaxation and increasing blood flow,...
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