Summary of this article

The test, available starting at 6 weeks gestation, is 100% accurate. Here is some important information to help you get accurate results early and have peace of mind for the duration of your pregnancy.

Development and comprehensive evaluation of a noninvasive prenatal paternity testing method through a scaled trial（Liao Chang et al)

Key points
The percentage of fetal DNA increased slowly in the second trimester and rapidly from the last trimester to birth.
A non-invasive prenatal paternity and paternity testing (NIPPT) method based on a targeted sequencing strategy was developed.
For the first time, the efficiency, reliability and sensitivity of NIPPT were systematically evaluated through a large-scale trial.
The results suggest that NIPPT can accurately determine parent-child relationships from the sixth week of conception to birth.

It says the above. What caught my attention in this paper was that only SNPs are used, but 5457 locations must be measured.

In a large study of 349 cases, NIPPT can determine parent-child relationships with 100% accuracy from the 6th week of pregnancy to birth.

This was the case.

Citation.

https://www.sciencedirect.com/science/article/abs/pii/S1872497319300109

医師監修監修日：2024年8月30日

岡博史（おかひろし）

医師・医学博士／ヒロクリニック統括院長

YouTubeチャンネルなどを通じて、遺伝子やNIPT（新型出生前診断）についてわかりやすく発信しています。