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Express Delivery

At Tokyo Ekimae Clinic

Shortest Next Day

Test Records

Safe and Fast

62,000Cases

Only in Hiro Clinic

Positive Score

&Positive Hit Rate

Combined Report

No. of Clinics

Nationwide

125 Clinics

Hiro Clinic NIPT
Survey of examinee satisfaction!

「2024年7月NIPT(新型出生前診断)に対する満足度」に関するアンケート調査を実施しました

Why choose Hiro Clinic?

“Only at Hiro Clinic can get all combinations”

– Illumina –

– Medicover –

Vanishing Twin on
chromosomes 21,
18 and 13
XXYY
Four types of
microdeletion
syndromes
Accuracy of twins
Features of our company
Tests available in
obstetrics and gynaecology

What is Illumina?

NIPT testing is offered primarily using next-generation sequencing (NGS) technology. This test non-invasively tests for chromosomal abnormalities in the foetus during pregnancy and screens for conditions such as Down syndrome and trisomy.

What is Medicover?

It offers NIPT testing using proprietary technology. In addition to screening for chromosomal abnormalities in the foetus, it also provides information on the sex of the foetus and the amount of free DNA in the pregnancy.

Differences between Early Next Generation NIPTs and
Initial NIPTs

	Early Next Generation NIPT	Initial NIPT
Implementing agency	Hiro Clinic	General obstetrics and gynecology
Target	Anyone who is pregnant can test	Basically only for high-risk individuals
Number of weeks	Pregnancy confirmed by echo About 6 weeks onwards	From 10 weeks
In charge	Doctor	Counsellor
Inspection items	Total autosomal aneuploidy Test for chromosomal abnormalities, including chromosomes 21, 18 and 13 Sex chromosome aneuploidy Testing of sex chromosomes (X or Y chromosomes) Partial deletion-duplication Testing for deletions and duplications of chromosomes 1-22 Microdeletions (four types) Tests for specific missing chromosomes Recessive genetic disorders (228 types) Tests for genetic variants from parents’ genes that may cause foetal disease	Chromosome 21,18,13 trisomy only (Test for chromosome 21,18,13 abnormalities)
Amniotic fluid test	Refer patients to appropriate partner clinics (Assisted amniotic fluid support available)	Referral to almost all university hospitals

NIPT at Hiro Clinic
Learn more!

The only NIPT test in Japan with an
exclusive contract with Medicover

Hiro Clinic is the only company in Japan with an exclusive contract with Medicover.

Medicover’s NIPT is more technically advanced than conventional NIPT tests, which also require international patents. In addition to four types of microdeletion syndromes, 228 serious recessive genetic disorders, and in South East Asia only the Tokyo Health Laboratory, with which Hiro Clinic is affiliated, provides the technology. Hiro Clinic is the only laboratory in the country that carries out the test, so the results are available quickly.

We have experienced Japanese Society of Obstetrics and Gynaecology specialists and Japanese Society of Human Genetics-certified clinical geneticists on staff to meet the various needs of pregnant women. We also offer a wider range of tests and advanced technology.

Medicover (https://www.medicover.com/)

NIPT at Hiro Clinic
5 reassurances

1 Doctor’s response from the first visit
While genetic counsellors often examine patients for early NIPT, Hiro Clinic’s doctors are available from the initial consultation. In addition, experienced specialists from the Japanese Society of Obstetrics and Gynaecology are on staff.

2ISO certification
Hiro Clinic’s laboratories and server management company are ISO 9001 and ISO 27001-certified, ensuring thorough inspection systems and information management.
‘What is ISO9001 certification?’ ‘What is ISO27001 certification?’

3CAP certification
Dec 2023 CAP certification renewed.
The laboratory that carries out NIPT testing at HIRO CLINIC has obtained CAP (College of American Path – ologists) certification, which is valuable as only two (2) laboratories in the country have obtained CAP certification for NIPT testing. This ensures that testing accuracy and procedures are guaranteed by an external organisation.
This certification is renewed every two years, when CAP auditors from all over the world visit the hygiene laboratory and inspect whether inspections are carried out in accordance with the rules of the certification body. The survey verifies that the equipment and personnel are managed and operated correctly, and that errors are verified and reported when they occur and corrective action is taken correctly. Renewal of this certification must be supervised by a laboratory director who has performed administrative tasks at a CAP certification body, and regular verification must be carried out.
Additionally, what sets CAP apart from ISO is its biannual verification. During this verification, the actual specimens are sent by the CAP governing body to each facility to verify that the tests are consistent across CAP facilities.

4Fast and secure in-country inspections
The clinic specialises in NIPT testing in Japan and carries out strict quality control to provide high accuracy testing for your peace of mind. We guarantee peace of mind with reliable information and expertise from the highest standard of NIPT testing in Japan.

5Thorough management of personal data
The web server and data server are operated separately on this website, and this design minimises the risk of personal data leakage. Your data is stored in a secure environment, preventing unauthorised access by third parties.
“About the Tokyo Sanitary Inspection Laboratory”

These factors ensure that the clinic’s website maintains high standards of security and protection of personal data, providing a safe and secure environment for customers to use the site.

World Class Next Generation NIPT

New users here

Registered users here

24hours reservation available

Benefits of Hiro Clinic

Hiro Clinic has a range of more detailed tests that are not available in obstetrics and gynaecology.

Benefit Fast and accurate!

Microdeletion diseases can be tested for in-country.

Benefit Only at Hiro Clinic!

Partial deletion and duplication of disease tests.

Benefit More detailed!

228 recessive genetic diseases can be checked.

Benefit Gender can also be known!

Sex chromosome test with a high frequency of aneuploidy.

Benefit Recommended for aged 35 and over!

All chromosomes 1-22 can be tested.

Benefit Credit card accepted!

Various credit cards are accepted as payment.

Do you have these concerns
during pregnancy?

I am worried that my baby has Down’s syndrome…add

Reasonable testing plans are available to test for Down’s syndrome only.

Click here for a single test for Down’s syndrome
I want to test now! Can I get an appointment?add

Same-day bookings are possible, depending on availability.
Reservation via the web is available 24 hours a day.

Click here to book
How long will it take for the test results?add

When using the express delivery service, we will notify you of the test results in as little as 2 days.
Additionally, 95% of customers receive their results within 8 days.

The average result reporting time for the F plan, G plan, and B plan is around 5 days.
The average result reporting time for the FM plan, GM plan, BM plan, AM plan, Oms plan, Om plan, Hms plan, Hm plan, A plan, O plan, and H plan is around 10 days.

※The reporting time may vary depending on the test items and the number of samples.

※In order to keep prices low, multiple samples are tested in batches. The number of days is calculated as if the sample arrived at the laboratory on day 0.

Click here to book

Other FAQs

Key points of
NIPT

No direct risk of invasion (damage) to the foetus
add

There are also a number of risks of invasion to the foetus, including amniotic fluid sampling by puncture of the mother in definitive tests and miscarriage due to transvaginal chorionic villus sampling. There is a 1/300 chance of miscarriage with amniotic fluid testing and a 1/100 chance of miscarriage with chorionic villus testing.
NIPT is an excellent nonconclusive test because it requires only a blood sample from the mother and does not directly invade (damage) the foetus.

Click here for web reservation
If the fetal heartbeat is confirmed by echocardiography, the test can be performed
add

Conventional nonconclusive tests (maternal serum markers and combined tests) were not available until after 11 weeks of pregnancy at the earliest.
Hiro Clinic can be taken once the foetus’ heartbeat has been confirmed, so the health of the baby can be known at an early stage.

Click here for web reservation
High inspection accuracy
add

There are two criteria for measuring the accuracy of a chromosome test. One is ‘sensitivity’, which indicates the probability of being positive and remaining positive after birth. The other is ‘specificity’, which indicates the probability of being negative and remaining negative after birth.
NIPT is highly accurate, with a sensitivity and specificity of 99.9% in testing for chromosome 21 (Down’s syndrome), and can more accurately detect the number of abnormal chromosomes in a baby.

Click here for web reservation
No age restrictions
add

There are no special age limits for NIPT at Hiro Clinic NIPT.
There are also no restrictions, such as the fact that couples must be accompanied by their spouses to receive the service.

Click here for web reservation

Philosophy of Hiro Clinic NIPT

Respect for the right to know: We respect the “right to know” of pregnant women and their families so that they can have a safe and healthy birth.

Towards a proper understanding of NIPT: NIPT aims to be widely understood not only to provide information on the health of the foetus, but also to maintain the health of the mother.