Guide how to take the test

Reservations for NIPT can be made through the Hiro Clinic Website.
All Hiro Clinic NIPT visits are by appointment only in order to shorten the waiting time of patients.

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Hiro Clinic NIPT
You can make a reservation in just 2 steps!

Book an appointment

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Make a NIPT Reservation in 2 steps
(Information on how to book an appointment)

Step. 1 Make a tentative reservation by selecting
a date, time and clinic
step.1
    1. Tentative Reservation of Visit

      Please make a reservation by selecting your expected delivery date, preferred clinic, and the date and time of your visit on the dedicated reservation page.

    2. Confirmation email of tentative reservation

      An e-mail will be sent to you confirming the completion of your tentative reservation. Please complete the reservation process from the URL provided.

Step 2 Complete your appointment by filling out
the consent form & medical questionnaire
step.2
    1. Log in to your Mypage

      Please log in to MyPage with the URL, ID and password provided in the e-mail of your tentative reservation.

    2. Confirm your Consent Form

      From the Consent Form Confirmation page, please read the Consent Form and click the
      “I Agree” button.

    3. Fill in Medical Questionnaire

      Please fill in the items on the medical questionnaire from ‘Medical Questionnaire’ page.

    4. Select a Test Plan (Mutual Aid Society Membership)

      Please select your desired test plan from “Select Test Plan”.
      You will then receive a confirmation email.

    5. Upload your Utrasound image & Maternal and Child Health Handbook

      Upload the ultrasound images and the Maternal and Child Health Handbook by clicking ‘Upload Image’.

    6. Watch the Explanation Video

      Make sure to watch the video explanation of the test by clicking on ‘Prior to taking the NIPT Test’.

    7. Reservation Complete

      This completes your appointment. Please come to the clinic on your selected date and time.

网站上马上预约

Hiro Clinic NIPT
You can make a reservation in just 2 steps!

Book an appointment

WEBから予約する

Test Guide & Procedure

Consultation and Explanation of the Testing during your Visit
step.3
    1. Visit during your Reserved Date & Time

      Please come to the clinic on the date and time specified at the time of your appointment.

    2. Watch the NIPT Explanation Video

    3. Talk with a Doctor

      The doctor will interview the patient and explain about NIPT.

    4. Signing of Consent Form

      If you agree with the explanation, you will be asked to fill out a consent form.

    5. Blood Collection

      10 ml of blood will be drawn.

    6. Payment

      Payment must be made in cash or by credit card.
      Payment of Mutual Aid Society fees is by cash only.

    7. Testing Complete

      This completes the NIPT test. Please wait until the test results are displayed on your My Page.

Verification of Analysis by Laboratory & Release of Results
step.4
    1. Sequencer analysis and checking done by a clinical laboratory technician

      After blood samples are collected, they are transported to the Second Tokyo Clinical Laboratory for sequencer analysis.
      After the sequencer analysis, a nationally certified clinical laboratory technician visually checks the test results for errors. This may take several hours.

    2. Download test results on ‘My Page’

      Results, including the sequencer analysis process, are usually delivered within 2~5 days (usually within 3~6 days for some clinics and partner facilities) after the blood collection.
      Please note that the express delivery option is available at all HIRO CLINIC NIPT clinics except the partner facilities (delivery within 2~3 days after blood collection).
      Test result reports will be available for viewing for 3 months after they are released.
      Result Paper

    3. Medical Examination with a Doctor

      We provide a consultation with your doctor on the day of your NIPT test, which is included in the cost of the test.

      If you wish to see a doctor on a day other than the examination day, you will be charged an additional consultation fee.
      (20 minutes:¥4,000 (¥4,400 including tax)

      If you wish to be examined, please make a request through My Page at least 2 days prior to the examination.
      If you wish to see a doctor the day before or on the same day, please call us. Depending on the schedule of the doctor in charge, we will accept your request for an appointment if it is possible.

网站上马上预约

Hiro Clinic NIPT
You can make a reservation in just 2 steps!

Book an appointment

WEBから予約する

What NIPT (Non-invasive Prenatal Test) results
can tell us about the baby

Diseases detected by NIPT (Non-invasive Prenatal Test)

Positive NIPT test results can indicate the following diseases:

  • Trisomy 21 (Down’s syndrome)
  • Trisomy 18 (Edwards syndrome)
  • Trisomy 13 (Patau syndrome)
  • Aneuploidy of sex chromosomes
  • Klinefelter’s syndrome
  • Turner syndrome
  • XXX syndrome
  • XYY syndrome
  • Identification of sex chromosomes
  • All autosomal whole region partial deletion disease

For details, see Diseases detected by NIPT (Non-invasive Prenatal Test)

Diseases detected by NIPT (Non-invasive Prenatal Test)
Diseases detected by NIPT (Non-invasive Prenatal Test)
...

Time until test results

Test results are usually delivered within 2~5 days (usually within 3~6 days for some clinics and partner facilities) after blood collection. For Hiro Clinic NIPT clinics (excluding partner facilities), an express delivery option is available (delivery within 2~3 days of blood collection).

Flow of NIPT Test

※Careful with the volume of the audio.
  • Test results are usually delivered within 2~5 days (usually within 3~6 days for some clinics and partner facilities) after blood collection. For Hiro Clinic NIPT clinics (excluding partner facilities), an express delivery option is available (delivery within 2~3 days of blood collection).
  • Results are provided through Online or in person.
    Mailing of the results report in paper is available at an additional cost.
  • In rare cases when the laboratory needs to reinspect the sample, an additional 3 days is needed to report the results.

网站上马上预约

Hiro Clinic NIPT
You can make a reservation in just 2 steps!

Book an appointment

WEBから予約する

Reminders regarding the NIPT Test

Read this before taking the test

NIPT is an accurate test with a sensitivity of 96.5% and specificity of 99.9% (median value for trisomy 21), but it is not a definitive test.
If a positive result is found or a positive result is withheld, a test (amniotic fluid test or chorionic villus test) must be performed to confirm the test result.

Proof of current pregnancy is required for the test. Please bring your Maternal and Child Health Handbook and an ultrasound image.

When the test result is an error

If there is an error in the results, we will retest free of charge only if there was an error in the technical aspects of the test, such as insufficient amount of blood collected.
There hasn’t been an error happened in Hiro clinic NIPT and the laboratory deems it is not necessary to retest.
We do not recommend retesting because it is highly likely that the same error will occur.

Cancellation

To cancel your reservation, call us or fill out our contact form at least one business day prior to the appointment.
Please make sure to select the NIPT clinic of your reservation in the selection, enter your cancellation details in the ‘Inquiry Details’ section, and then click ‘Confirmation’ to complete the process.

Please contact us at least one business day prior to your appointment using the Contact Form to reschedule your appointment.
Also, if you have difficulty coming to the clinic due to severe morning sickness or for other reasons on the day of your visit, please be sure to notify us by calling the clinic.

Questions or inquiries about the testing

If you have any questions about the testing, you may first see the Frequently Asked Questions (FAQ).
If you cannot find your question, please contact us using the contact form.

Contact us by phone

※ Calls can be made only from within Japan

What is NIPT (Non-invasive Prenatal Test)?

What exactly is NIPT?

(NIPT) is a new non-invasive prenatal test that uses only a blood sample from a pregnant woman to determine whether the fetus has a chromosomal abnormality such as Down syndrome.

What will NIPT tell us?

An abnormality in which the number of chromosomes, which normally have two each, is greater than or less than one, is called a numerical chromosome abnormality.

The NIPT at Hiro Clinic NIPT can detect trisomies as well as monosomies and other numerical abnormalities.

In addition, structural abnormalities such as missing or duplicated chromosomes can also be reported. For details, please read What is NIPT (Non-invasive Prenatal Testing)?

What is NIPT (Non-invasive Prenatal Testing)?
What is NIPT (Non-invasive Prenatal Testing)?
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