¥170,000  ( ¥187,000 incl. tax )  
¥214,500for twins, including tax
Via Partner Clinic
¥190,000
(¥209,000 including tax)
¥236,500 for twins, incl. tax.

The Junior Plan examines chromosome numbers 13 (Patau Syndrome), 18 (Edwards Syndrome), and 21 (Down Syndrome) which are among the most frequent congenital diseases caused by changes in the number of autosomal chromosomes, which are 22 pairs of chromosomes (44 chromosomes) + partial deletions of all regions of chromosomes 1, 2, 3, 4, 5, 7, 8, 10, 15, 18, 20, 21, and 22. Syndromes will be identified for the three known types. Deletions and duplications in other regions will also be reported.

This plan is recommended by Hiro Clinic NIPT, which has tested over 17,000 people*. (*As of March 11, 2022)

Gender can also be identified.

  • ● Tests abnormalities in Chromosomes 13,18 and 21.

    13
    18
    21
  • ● Tests chromosome 1, 2, 3, 4, 5, 7, 8, 10, 15, 18, 20, 21, 22 whole region for partial deletion and duplication disease abnormalities.

    Deletion
    Duplication
    1
    2
    3
    4
    5
    7
    8
    10
    15
    18
    20
    21
    22
    X

    (Excluding Y)

  • ● For single baby, you will be informed of the sex chromosome abnormalities and gender/sex of the baby.

    XY
    XX
    XO
    XXY
    Others …
  • ● For twins, we will be informed whether or
    not a Y chromosome is present.

    Y

Diseases that can be detected by this test

ChromosomeDisease/DisorderOccurrence rate
21Down syndrome1 in 1,000
18Edwards syndrome1 in 6,000
13Patau syndrome1 in 10,000
ChromosomeDisease/DisorderOccurrence rate
XKlinefelter’s syndrome1 in 1,000
XTurner’s syndrome1 in 2,500
XXXX syndrome1 in 1,000
YXYY syndrome1 in 1,000

ChromosomeDisease/DisorderOccurrence rate
1Alagille syndrome1 in 30,000 to 70,000
11q21.1 microdeletion syndrome 
11p36 deletion syndrome1 in 4,000 to 10,000
11q21.1 microduplication syndrome
2Nephronophthisis
2Holoprosencephaly
2Albright syndrome-like metacarpal/brachymetatarsia
ChromosomeDisease/DisorderOccurrence rate
33q29 microdeletion syndrome
4Wolf-Hirschhorn syndrome1 in 50,000
5Cornelia de Lange syndrome1 in 30,000 to 50,000
5Cri-du-chat syndrome1 in 20,000 to 50,000
5Sotos syndrome1 in 10,000 to 20,000
7Pallister-Hall syndrome
7Greig’s cerebral polydactyly
ChromosomeDisease/DisorderOccurrence rate
7Saethre-Chotzen syndrome
7Total anterior encephalocele type 3
7Charge syndrome
7Williams syndrome
88p23.1 microdeletion syndrome
8Tricho-rhino-phalangeal syndrome type I(TRPS type I)
8Langer-Giedion syndrome
ChromosomeDisease/DisorderOccurrence rate
88p23.1 microduplication syndrome
10Chro. 10q24 Duplication Syndrome
15Prader-Willi syndrome1 in 16,000
15Angelman syndrome1 in 15,000
15Hypergrowth and intellectual disability
20Alagille syndrome

The following is a list of the major X-linked recessive inherited diseases.

Boys may develop the disease when they have a close relative with X-linked recessive inherited disease, while girls are often asymptomatic carriers.
Note that NIPT cannot determine the presence or absence of X-linked recessive inherited disease. However, it is possible to verify the possibility of developing X-linked recessive inherited disease in a relative by examining the sex of the child.

The following are typical X-linked recessive genetic disorders:

ChromosomeDisease/DisorderOccurrence rate
XX-linked agammaglobulinemia (XLA)Boys 1 in 100,000
XGlucose-6-phosphate dehydrogenase deficiency1 in 1,000
XX-linked hypophosphatemic rickets (XLH)1 in 20,000
Xred-green colorblindness1 in 20 to 500
XHemophilia1 in 4 boys with maternal retention
ChromosomeDisease/DisorderOccurrence rate
XDuchenne muscular dystrophy (DMD)60% for boys 1 in 3,500 maternal retention
XX-linked ichthyosis1 in 2,000 to 6,000
XKallmann syndrome1 in 10,000
X, YLeri-Weill dyschondrosteosis (LWD) 

Recommended to:

If you are curious about NIPT but would like to have a comprehensive test.
Those who have experienced repeated miscarriages.
Those who have experienced stillbirths.
This NIPT test is recommended for those who have a close relative with a disability/disorder of some kind.
It is also recommended for those who want to take this opportunity to examine in detail.
This plan is designed based on a study involving over 17,000 pregnant women in Japan to determine the most appropriate test content based on age limitations, target chromosomes, and focus on pregnant women in Japan.

We recommend that you consider a full-set plan that provides detailed examination to ensure your baby’s safety.

The Junior plan is for the examination of one fetus (single fetus) or twins.
All clinic tests are performed in Japan, and results are usually delivered within 2~5 days (usually within 3~6 days for some clinics and partner clinics) from the time of blood collection. Please note that an express delivery option is available at all Hiro Clinic NIPT clinics (delivery within 2~3 days of blood collection), except for partner clinics.

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